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Manidipine Hydrochloride (GMP approved) buy - large image1
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Manidipine Hydrochloride (GMP approved)

GMP

Unit Price: Get Latest Price
CAS No.:

89226-75-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Packaging:

5kg/drum, 10kg/drum, 20kg/drum, 25kg/drum

Price valid (until):

2024-04-04

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Manidipine Hydrochloride,Lercanidipine Hydrochloride 132866-11-6,Azilsartan Kamedoxomil 863031-24-7,Quetiapine Fumarate 111974-72-2,Manidipine Intermediates 841-77-0,Lercanidipine Intermediate 74936-72-4

  • Product Description

  • Seller Information

  • Description

    Product name: Manidipine Hydrochloride

    Structure chart:

    Shop Manidipine Hydrochloride (GMP approved)-Detailed Image 1


    Molecular formula: C35 H38 N4 O6 .2HCl

    Molecular weight: 683.62

    Chemical name:

    2-(4-Benzhydrylpiperazin-1-yl)ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate dihydrochloride

    CAS No.: 89226-75-5

    Quality standard: enterprise standard

    Assay: ≥99.0%

    Uses: Preparation of Manidipine Hydrochloride related preparation, treatment of hypertension.

    Certificates

    Basic Info
    Product Name:

    Manidipine dihydrochloride

    Other Name:

    3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,3-[2-[4-(diphenylmethyl)-1-piperazinyl]ethyl] 5-methyl ester,hydrochloride (1:2);3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester,dihydrochloride;CV 4093;Franidipine hydrochloride;(±)-Manidipine dihydrochloride;Calslot;Manidipine dihydrochloride;126229-12-7

    CAS No.:

    89226-75-5

    Molecular Formula:

    C35H38N4O6.2ClH

    InChIKeys:

    InChIKey=JINNGBXKBDUGQT-UHFFFAOYSA-N

    Molecular Weight:

    683.62

    Exact Mass:

    682.232

    EC Number:

    1308068-626-2

    DSSTox ID:

    DTXSID9020796

    HScode:

    2933990090

    Characteristics
    PSA:

    117

    XLogP3:

    6.48280

    Melting Point:

    157-163°; mp 174-180°; mp 167-170°

    Boiling Point:

    722ºC at 760 mmHg

    Water Solubility:

    Soluble in DMSO. Slightly soluble in water and ethanol /n

    Toxicity:

    LD50 in male, female mice, male, female rats (mg/kg): 387, 340, 222, 199 s.c.; 62.2, 68.0, 66.5, 48.8 i.p.; 190, 171, 247, 156 orally (Chiba)

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 3, Oral

    Reproductive toxicity, Category 2

    Specific target organ toxicity – repeated exposure, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H301 Toxic if swallowed

    H361 Suspected of damaging fertility or the unborn child

    H373 May cause damage to organs through prolonged or repeated exposure

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P318 IF exposed or concerned, get medical advice.

    P319 Get medical help if you feel unwell.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Manidipine Hydrochloride,Lercanidipine Hydrochloride 132866-11-6,Azilsartan Kamedoxomil 863031-24-7,Quetiapine Fumarate 111974-72-2,Manidipine Intermediates 841-77-0,Lercanidipine Intermediate 74936-72-4

    Location:

    Jian an Fine Chemical Industrial Park, Xuchang City, Henan Province China

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    120

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    101-200

    Year of Establishment:

    2007

    Certifications:

    Pharmaceutical production license

    Company Profile
      Xuchang Hengsheng Pharmaceutical Co., Ltd. (Hengsheng) was built in January 2007. It is a technological enterprise specialized in the development, production and sale of pharmaceutical products which are APIs, Formulation and API intermediates.
      Hengsheng is located at Zhangpan town in Xuchang, a city in the middle of Henan province. The site is near by Jing-Zhu Highway (Beijing- Zhuhai) and Jing-Guang Railway& High-Speed Railway (Beijing- Guangzhou), in the south of Zhengzhou and 40 km away from Zhengzhou Xinzheng International Airport. It is easy to arrive at the site.
      Hengsheng is a developing modern manufacturing site with four synthesis workshops, one for drug synthesis workshop to manufacture APIs, the others for Formulation and API intermediates. The synthesis workshop of API manufacturing has passed China GMP check in Jan. 2018. All of other facilities is completed and meets the requirement of API manufacturing activities within this workshop.
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