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Factory Supply Research Chemical Pure 98% NP-12 NP 031112 Tideglusib Raw Powder CAS 865854-05-3 buy - image1

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Factory Supply Research Chemical Pure 98% NP-12 NP 031112 Tideglusib Raw Powder CAS 865854-05-3 buy - image3

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Factory Supply Research Chemical Pure 98% NP-12 NP 031112 Tideglusib Raw Powder CAS 865854-05-3

Name: Factory Supply Research Chemical Pure 98% NP-12 NP 031112 Tideglusib Raw Powder CAS 865854-05-3
Brand: HORLDEN
SKU: pr2403211072
Price: 22 USD
Availability: InStock

TDS 9 Inquiries

Unit Price:

$22-28/G FOB

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CAS No.:

865854-05-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

HORLDEN

Packaging:

10g/bottle

Price valid (until):

2027-06-01

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XI'AN HORLDEN BIO INDUSTRIES INC

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Chemical,Intermediate,5-amino-1mq,SLU-PP332,Tirzepatide,Peptide

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Product Description
Seller Information
Inquiry History

Description

Shop High quality Pure NP 031112 Tideglusib raw powder CAS 865854-05-3-Detailed Image 1

Shop High quality Pure NP 031112 Tideglusib raw powder CAS 865854-05-3-Detailed Image 2

Product Name	Tideglusib
CAS NO.	865854-05-3
Purity	99%
Molecular Formula	C19H14N2O2S
MOQ	10 g

Tideglusib (NP031112, NP-12) is an irreversible, non-ATP competitive inhibitor of GSK-3β with an IC50 of 60 nM in cell-free assays. It does not inhibit the Cys kinase homologous to Cys-199 located in the active site. . Phase 2.

Tideglusib (also known as NP031112, NP-12) is a derivative of small heterocycli thiadiazolidino. It is an irreversible, non-ATP-competitive GSK-3β inhibitor that can inhibit GSK-3β WT and GSK-3β C199A with IC50 values of 5 nM and 60 nM, respectively. It is currently in clinical trials for Alzheimer's disease. Tideglusib can reduce the phosphoration of tau protein and the accumulation of amyloid plaques, reduce the loss of neurons in the hippocampus and entorhinal cortex, and improve spatial memory deficits. It also shows neuroprotective and anti-inflammatory activities in multiple animal models.

Shop Factory Supply Research Chemical Pure 98% NP-12 NP 031112 Tideglusib Raw Powder CAS 865854-05-3-Detailed Image 3

You can ask us for quotation and product information via Email, Phone, WhatsApp and other channels.

Email: rock@horlden.com
WhatsApp/ wechat: +86 18829283179

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1.What's your payment terms?

Standard terms: T/T in advance. Also L/C at sight is acceptable for large amount.

2.What's your shipping time?

We have bulk in stock, which means we can ship it to you immediately.

3.How do you ensure the quality of your products?

Strict QC with 6 steps testing from raw material purchase to finished product.

4.How do you ship the order normally?

For large qty order,ship the goods by sea. For small qty order, by air or express. We supply optional express for you, including DHL, FEDEX,UPS,TXT,EMS,and so on.

5.What's your loading port?

Usually Beijing, Shanghai, Qingdao, Tianjin, Guangzhou

Certificates

Basic Info

Product Name:

Tideglusib

Other Name:

1,2,4-Thiadiazolidine-3,5-dione,2-(1-naphthalenyl)-4-(phenylmethyl)-;2-(1-Naphthalenyl)-4-(phenylmethyl)-1,2,4-thiadiazolidine-3,5-dione;4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione;Tideglusib;NP 12;NP 031112;945421-01-2;1073650-08-4

CAS No.:

865854-05-3

Molecular Formula:

C19H14N2O2S

InChIKeys:

InChIKey=PMJIHLSCWIDGMD-UHFFFAOYSA-N

Molecular Weight:

334.39166

Exact Mass:

334.39

UNII:

Q747Y6TT42

DSSTox ID:

DTXSID90235682

Categories:

Inhibitor Drugs

Characteristics

PSA:

65.9

XLogP3:

4.3

Appearance:

white to beige

Density:

1.4±0.1 g/cm3

Melting Point:

148-150ºC

Boiling Point:

511.3ºC at 760 mmHg

Flash Point:

263.0±28.2 °C

Refractive Index:

1.735

Water Solubility:

Sparingly soluble with water.DMSO: >15mg/mL

Storage Conditions:

2-8°C

See More Tideglusib Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Tideglusib Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Chemical,Intermediate,5-amino-1mq,SLU-PP332,Tirzepatide,Peptide

Location:
10712，floor7,Unit 1,Buiding5,Silk Road International Creative Dreamwordks,No.3639,xi'an,shaanxi

Payment Terms:
100% TT in advance

Average lead Time:
7

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
11-50

Year of Establishment:
2015

Xi'an Horlden Bio Industries Ins is committed to promoting health application products such as chemical daily necessities, APIs, pharmaceutical intermediates and Cosmetic raw materials.

We have established friendly business relationships with hundreds of customers from over 50 countries and regions. Our team is committed to providing customers with the highest quality products at reasonable prices and satisfactory service. For many years, our company has won the trust and favor of our customers with high-quality products, first-class services, and competitive prices.

We will create the highest quality and most stable supply channel for customers, adhering to the spirit of serving customers, relying on strong funds and good cooperation reputation in the industry, to provide customers with higher quality products and services. At the same time, we are willing to strengthen exchanges and sincere cooperation with domestic and foreign merchants to create a better future together. It is your best supplier.

Welcome to Xi'an Horlden Bio Industries Ins !

Inquiry History

9 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	High Purity Tideglusib 99% Powder CAS 865854-05-3 EGC-Tideglusib Powder	1 MT	Oct 31, 2023
United States	Tideglusib	25 G	Jun 13, 2026
Russia	Tideglusib	0.1 KG	Jan 26, 2025
United States	Tideglusib	100 MG	Apr 17, 2024
Slovenia	Tideglusib	1 KG	Mar 20, 2024
Spain	Tideglusib	1 KG	Mar 29, 2025
United Kingdom	Tideglusib	25 G	Jun 8, 2026
United States	Tideglusib	10 G	Apr 25, 2024
United States	Tideglusib	100 MG	Apr 16, 2024

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