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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Tideglusib for Sale > NP-12 NP 031112 Tideglusib raw Powder CAS 865854-05-3 Tideglusib
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NP-12 NP 031112 Tideglusib raw Powder CAS 865854-05-3 Tideglusib buy - image6

NP-12 NP 031112 Tideglusib raw Powder CAS 865854-05-3 Tideglusib

COA TDS 12 Inquiries

Unit Price: Get Latest Price
CAS No.:

865854-05-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shenzhen

Brand:

HS

Packaging:

25kg drum

Sample Available:

Yes

Price valid (until):

2026-10-21

Company Type:
Manufactory
Location:
China
Payment Terms:
L/C,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
7 days
Qualification:
Main Products:

Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive

  • Product Details

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  












    whasapp:+8615202961574
    Email:gary@xahnb.com

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    Items Standard
    Test Results

    Identification

    A.H-NMR:Comply with the structure
    Complies
    B.LC-MS:Comply with the structure
    Complies
    C.The IR spectrum of sample should be identical with that of reference standard.
    Complies
    D.HPLC-ESI-MS
    The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.







    Complies
    Loss on drying % ≤2.0
    0.19
    Heavy metals ppm ≤10 
    <10
    Moisture % ≤1.0
    0.1
    Sulphated ash % ≤0.5 determined on 1.0 g.
    0.009
    Residue on ignition % ≤0.1
    0.03

    Related Substances %

    Unspecified impurities: for each impurity ≤0.10 <0.10
    Total Impurity ≤0.5 0.18
    Purity % ≥99.0
    99.7
    Assay % 99.0 ~101.0 (anhydrous substance).
    99.8
    Storage Preserve in well-closed, light-resistant and airtight containers.
    Complies


    Xian Harmonious Natural Bio- Technology Co., Ltd was founded in 2017, and located in Xlan International Logistics Industrial Zone, Xran City. ShaanxtProvince, China. Now it is the leading researcher and one of the biggest manufacturer in high technology APl area.

    There are 8 experts in our research team. We insistin innovation and produce high quality products. And GMP standard workshop and complete stainlessextraction equipment.

    We have 2 sales deparments over 20 people and sellour products allover the word. We also have strong professional research and developmentteamtalented personnel and completely equipped laboratoy for the quality controlling. Various Detection Device is equipped in HNB company, such as HPLCGC, Spectrophotometer, AAS, Polarimeter, Auto titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on
    HNB mainly engaged in export of products incuding,wthoutlimitation., pharmaceutical raw materials both for vet and human, also Vitamins, Amino Acidsminerals, peptides, plant extract, feed and food additives. Our company's business is based on Honest, Trustwortly, Constanty to Go Beyond andAchieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends from both home and abroad.
    Passion to innovate, Power to deliver ! 


    Delivery:
    In about 3 working days after the receipt of payment, we will follow up the delivery until you receive it.
    Express way as the following is:
    (Shipping : TNT, Fedex, DHL,USP,EMS and so on)

    (By air,by sea,by rail...)


    Packaging: 
    Drum & plastic bags, Aluminum foiled bag, Zip lock bags 
    Our Company:
    Our company advantage:
    1.Small order is acceptable
    2.Can provide sample for you
    3.Have self-export rights

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    Q1  Can i get some samples
    A1  Yes, we can supply the free sample, but the shipping cost be paid by our customers.
    Q2  How to start orders or make payments
    A2  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.                Payment by T/T,or Paypal or Escrow(Alibaba).
    Q3  How to confirm the Product Quality before placing orders
    A3  You can get free samples for some products,you only need to pay the shipping cost or arrange a   courier to us and take the samples. You can send us your product specifications and requests,we  will manufacture the products according to your requests.
    Q4  What's your MOQ
    A4  Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
    Q5  How about delivery leadtime
    A5  Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
    Q6  Is there a discount
    A6  Different quantity has different discount.
    Q7  How do you treat quality complaint
    A7  First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
    Q8  How to contact us
    A8 You can chat with us by Trademanager,MSN&Skype Online.
           You can choose your interested products and send inquiry to us.
           You can dial our telephone directly or send Email to us., you will get our reply.

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    ECHEMI Editorial Reference
    Tideglusib is an irreversible GSK-3 inhibitor with IC50s of 5 nM and 60 nM for GSK-3βWT (1 h preincubation) and GSK-3βC199A (1 h preincubation), respectively.
    Tideglusib is a member of the class of thiadiazolidines that is 1,2,4-thiadiazolidine-3,5-dione which is substituted by a naphthalen-1-yl group at position 2 and by a benzyl group at position 4. It is a non-ATP competitive inhibitor of glycogen synthase kinase 3beta (GSK3beta) and has neuroprotective effects. Currently under clinical investigation for the treatment of Alzheimer's disease and progressive supranuclear palsy. It has a role as an EC 2.7.11.26 (tau-protein kinase) inhibitor, a neuroprotective agent, an anti-inflammatory agent and an apoptosis inducer. It is a member of naphthalenes, a member of benzenes and a thiadiazolidine.|Tideglusib is under the investigation for the development of treatments for Alzheimer's disease and for progressive supranuclear palsy. It is reported to be a potent anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3). Tideglusib is being developed by the Spanish pharmaceutic company Zeltia group and its current status is withdrawn for the treatment of Alzheimer's disease as of 2012.

    Certificates

    Basic Info
    Product Name:

    Tideglusib

    Other Name:

    1,2,4-Thiadiazolidine-3,5-dione,2-(1-naphthalenyl)-4-(phenylmethyl)-;2-(1-Naphthalenyl)-4-(phenylmethyl)-1,2,4-thiadiazolidine-3,5-dione;4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione;Tideglusib;NP 12;NP 031112;945421-01-2;1073650-08-4

    CAS No.:

    865854-05-3

    Molecular Formula:

    C19H14N2O2S

    InChIKeys:

    InChIKey=PMJIHLSCWIDGMD-UHFFFAOYSA-N

    Molecular Weight:

    334.39166

    Exact Mass:

    334.39

    UNII:

    Q747Y6TT42

    DSSTox ID:

    DTXSID90235682

    Characteristics
    PSA:

    65.9

    XLogP3:

    4.3

    Appearance:

    white to beige

    Density:

    1.4±0.1 g/cm3

    Melting Point:

    148-150ºC

    Boiling Point:

    511.3ºC at 760 mmHg

    Flash Point:

    263.0±28.2 °C

    Refractive Index:

    1.735

    Water Solubility:

    Sparingly soluble with water.DMSO: >15mg/mL

    Storage Conditions:

    2-8°C

    Hazard Identification

    Classification of the substance or mixture

    no data available

    GHS label elements, including precautionary statements

    Pictogram(s) no data available
    Signal word

    no data available

    Hazard statement(s)

    no data available

    Precautionary statement(s)
    Prevention

    no data available

    Response

    no data available

    Storage

    no data available

    Disposal

    no data available

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive

    Location:

    6 floor Baoyilongji Building B Weiyang Area, Fengcheng 8 Road, Xi'an city, Shaanxi, 710000, China

    Payment Terms:

    L/C,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7 days

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    51-100

    Year of Establishment:

    2017

    Company Certificates
    • HNB BiotechISO ISO
    • HNB BiotechISO ISO

    Xi'an Harmonious Natural Bio-Technology Co., Ltd. was founded in 2010, and located in Xian

    International Logistics Industrial Zone, Xi'an City, Shaanxi Province, China. Now it is the

    leading researcher and one of the biggest manufacturer in high technology API area. 

     

    There are 8 experts in our research team. We insist in innovation and produce high quality

    products. And GMP standard workshop and complete stainless extraction equipment. 

    We have 2 sales departments over 20 people and sell our products all over the world.

     

    We also have strong professional research and development team, talented personnel and

    completely equipped laboratory for the quality controlling. Various Detection Device is

    equipped in HNB company, such as HPLC, GC, Spectrophotometer, AAS, Polarimeter, Auto

    titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.

     

    HNB mainly engaged in export of products including, without limitation, pharmaceutical raw

    materials both for vet and human, also Vitamins, Amino Acids, minerals, peptides, plant

    extract, feed and food additives.

     

    Our company's business is based on Honest, Trustworthy, Constantly to Go Beyond and

    Achieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends

    from both home and abroad.

     

    Passion to innovate, Power to deliver !

  • Inquiry History
    12 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    High Purity Tideglusib 99% Powder CAS 865854-05-3 EGC-Tideglusib Powder

    1 MT Oct 31, 2023
    United States

    Tideglusib

    25 G Jun 13, 2026
    United States

    Tideglusib

    100 G Sep 13, 2026
    Russia

    Tideglusib

    0.1 KG Jan 26, 2025
    United States

    Tideglusib

    100 MG Apr 17, 2024
    Slovenia

    Tideglusib

    1 KG Mar 20, 2024
    United States

    tideglusib

    1 G Oct 11, 2026
    United Kingdom

    Tideglusib

    25 G Jun 8, 2026
    United States

    Tideglusib

    10 G Apr 25, 2024
    United States

    Tideglusib

    100 MG Apr 16, 2024
    United States

    Tideglusib

    100 G Sep 17, 2026
    Spain

    Tideglusib

    1 KG Mar 29, 2025
    Post an enquiry for this product
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