Factory Supply High Quality Tideglusib Raw Powder cas 865854-05-3
TDS 11 Inquiries
865854-05-3
Top Product
98%
wuhan
Senwayer
1KG per foil bag, 25KG per drum.
Yes
2031-03-01
API,nutrition supplements,plant extract,peptide,HCG,6-Aminocaproic acid
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceTideglusib is an irreversible GSK-3 inhibitor with IC50s of 5 nM and 60 nM for GSK-3βWT (1 h preincubation) and GSK-3βC199A (1 h preincubation), respectively.
Tideglusib is a member of the class of thiadiazolidines that is 1,2,4-thiadiazolidine-3,5-dione which is substituted by a naphthalen-1-yl group at position 2 and by a benzyl group at position 4. It is a non-ATP competitive inhibitor of glycogen synthase kinase 3beta (GSK3beta) and has neuroprotective effects. Currently under clinical investigation for the treatment of Alzheimer's disease and progressive supranuclear palsy. It has a role as an EC 2.7.11.26 (tau-protein kinase) inhibitor, a neuroprotective agent, an anti-inflammatory agent and an apoptosis inducer. It is a member of naphthalenes, a member of benzenes and a thiadiazolidine.|Tideglusib is under the investigation for the development of treatments for Alzheimer's disease and for progressive supranuclear palsy. It is reported to be a potent anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3). Tideglusib is being developed by the Spanish pharmaceutic company Zeltia group and its current status is withdrawn for the treatment of Alzheimer's disease as of 2012.Certificates-
TDS
Basic Info-
Product Name:
Tideglusib
Other Name:1,2,4-Thiadiazolidine-3,5-dione,2-(1-naphthalenyl)-4-(phenylmethyl)-;2-(1-Naphthalenyl)-4-(phenylmethyl)-1,2,4-thiadiazolidine-3,5-dione;4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione;Tideglusib;NP 12;NP 031112;945421-01-2;1073650-08-4
CAS No.:865854-05-3
Molecular Formula:C19H14N2O2S
InChIKeys:InChIKey=PMJIHLSCWIDGMD-UHFFFAOYSA-N
Molecular Weight:334.39166
Exact Mass:334.39
UNII:Q747Y6TT42
DSSTox ID:DTXSID90235682
Categories:
Characteristics-
PSA:
65.9
XLogP3:4.3
Appearance:white to beige
Density:1.4±0.1 g/cm3
Melting Point:148-150ºC
Boiling Point:511.3ºC at 760 mmHg
Flash Point:263.0±28.2 °C
Refractive Index:1.735
Water Solubility:Sparingly soluble with water.DMSO: >15mg/mL
Storage Conditions:2-8°C
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
API,nutrition supplements,plant extract,peptide,HCG,6-Aminocaproic acid
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Location:
Room 707, Block A, Zhongxing Times Digital Trade Port, No. 79 Xudong Street, Hongshan District, Wuhan City
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Payment Terms:
TT against copy of documents,L/C
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Average lead Time:
10 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
51-100
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Year of Establishment:
2020
Company Certificates-
Verified supplier certificate
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SGS
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Inquiry History11 Inquiries
Country Product Purchase Quantity Date Posted 
United States
High Purity Tideglusib 99% Powder CAS 865854-05-3 EGC-Tideglusib Powder
1 MT Oct 31, 2023
United States
Tideglusib
25 G Jun 13, 2026
United States
Tideglusib
100 G Sep 13, 2026 
Russia
Tideglusib
0.1 KG Jan 26, 2025
United States
Tideglusib
100 MG Apr 17, 2024 
Slovenia
Tideglusib
1 KG Mar 20, 2024
United States
Tideglusib
100 G Sep 17, 2026 
Spain
Tideglusib
1 KG Mar 29, 2025 
United Kingdom
Tideglusib
25 G Jun 8, 2026
United States
Tideglusib
10 G Apr 25, 2024
United States
Tideglusib
100 MG Apr 16, 2024 Post an enquiry for this product
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