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503612-47-3 | ChemExpress buy - large image1
503612-47-3 | ChemExpress buy - image1

503612-47-3 | ChemExpress

19 Inquiries

Unit Price: Get Latest Price
CAS No.:

503612-47-3

Port:

shanghai

Packaging:

10 kg

Price valid (until):

2024-04-01

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

CRO

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Apixaban

    Apixaban in the treatment of Venous Thromboembolism(VTE) , API
    We can provide high-quality Apixaban and its derived impurities.


    Brand:ChemExpress
    CAS:503612-47-3
    Catalog_No:HY-50667
    Molecular Formular:C19H18ClN3O5S
    Molecular Weight:435.88


    Contact:
    TEL:+1-970-439-2030 (USA)、+86 (21) 5895-0125 (Global)
    Email:info@chemexpress.com



    Brand Introduction:
    ChemExpress focuses on providing small molecule and new modalities CDMO services for both pharmaceutical and biotech clients. Our comprehensive CRO & CDMO platform is engaged in the research and development, manufacturing and supply of regulatory starting materials, novel building blocks, intermediates, reference compounds, APIs and drug products. We are a one-stop service platform to support our client’s projects from early drug discovery, process development to commercialization.


    ChemExpress Services:
     
    Drug Discovery: synthetic chemistry; medicine chemistry; FTE/FFS services.

    Process Development: APIs and intermediates development; formulation development.

    New Modalities Development: ADC; peptide; oligonucleotide and so on.

    Manufactory: support production from milligrams to kilograms, both with GMP and non-GMP capabilities.

    Analytical Development & Quality Control: R&D testing; stability study; genotoxic impurity research and so on.

    Regulatory CMC Support

    Eany development services in Synthetic Chemistny:Providing serices related to high qualty compound synthesis,chemical custom synthesis and analytical chemistry.

    Pharmaceutical Chemistry eaniy development services: including high-throughput screening, drug synthesis, seding compounds, lead compounds, and IND fling support.

    Process development: Covers AP! & intermediates process development, validation, transfer, and formulation development.

    Commerial producion:it hasa research and development base forthe producion otapis intermediates and prenarations and provdes commeria prouction semices.

    CMC services: Provide one-stop CMC services, from lND to NDA stage of pharmaceutical research and development and dedlaration services, accelerate IND declaration.

    ADC drug and highly active drug development and production:  Provides a one-stop CRO & CDMO service for the small molecule aspect of ADC drugs, as well as customized ADC conjugation services. 

    Oligonucleotide drug process development and production: Provide oligonucleotide customized products and services to meet different needs.

    Analytical testing services and quality control: Provide integrated analytical testing services and drug quality research support

    ChemExpress committed to being a steadfast companion for our clients, gaining profound insight into their needs. Our focus is on accelerating the empowerment of global partners across the full spectrum, from preclinical stages to commercial production. This commitment aims for more streamlined drug development, swifter market entry, and an earlier positive impact on human health.


    Product details:https://www.chemexpress.com/product/HY-50667

    Basic Info
    Product Name:

    Apixaban

    Other Name:

    1H-Pyrazolo[3,4-c]pyridine-3-carboxamide,4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-;4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide;1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid amide;BMS 562247-01;Apixaban;Eliquis;1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide;1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxamide;1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridine-3-carboxamide

    CAS No.:

    503612-47-3

    Molecular Formula:

    C25H25N5O4

    InChIKeys:

    InChIKey=QNZCBYKSOIHPEH-UHFFFAOYSA-N

    Molecular Weight:

    459.504

    Exact Mass:

    459.50

    Characteristics
    PSA:

    111

    XLogP3:

    2.2

    Density:

    1.42

    Boiling Point:

    770.468ºC at 760 mmHg

    Flash Point:

    419.8±32.9 °C

    Refractive Index:

    1.705

    Water Solubility:

    Aqueous solubility: 40-50 μg/ml in 0.9% saline solutionAqueous solubility across the physiological pH range is approximately 0.04 mg/L

    Storage Conditions:

    Store at 20 deg C to 25 deg C (68 deg F-77 deg F); excursions permitted between 15 deg C and 30 deg C (59 deg F-86 deg F).

    Vapor Pressure:

    4.29X10-18 mm Hg at 25 deg C (est)

    Hazard Identification

    Classification of the substance or mixture

    Specific target organ toxicity – repeated exposure, Category 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H372 Causes damage to organs through prolonged or repeated exposure

    Precautionary statement(s)
    Prevention

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    Response

    P319 Get medical help if you feel unwell.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    CRO

    Location:

    1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA

    Payment Terms:

    TT against copy of documents

    Average lead Time:

    3

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    Above 1000

    Year of Establishment:

    2006

    Company Profile

    Founded in 2006, ChemExpress focuses on providing small molecule and new modalities CDMO services for both pharmaceutical and biotech clients. Our comprehensive CRO & CDMO platform is engaged in the research and development, manufacturing and supply of regulatory starting materials, novel building blocks, intermediates, reference compounds, APIs and drug products. We are a one-stop service platform to support our client’s projects from early drug discovery, process development to commercialization.

    Over the past 17 years, we have established a state-of-the-art QC/QA system aligning with ICH guidelines for pharmaceutical manufacturing. We provide our clients with high-quality products and CMC services across the entire life-cycle of drug development.


  • Inquiry History
    19 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Apixaban  

    20.00 KG May 27, 2025
    India

    Apixaban  

    50.00 KG May 29, 2025
    India

    Apixaban  

    20.00 KG May 27, 2025
    India

    Apixaban  

    40.00 KG May 27, 2025
    Italy

    Apixaban

    50.00 KG May 25, 2025
    India

    APIXABAN 

    1.00 KG Mar 25, 2025
    South Korea

    Apixaban

    100 KG Jan 25, 2024
    Brazil

    Apixaban for wholesale

    100 G Oct 25, 2023
    Bangladesh

    Apixaban

    300.00 KG May 30, 2025
    India

    Apixaban

    100.00 KG Nov 11, 2023
    India

    Apixaban

    10 G Jun 2, 2026
    India

    Apixaban

    260.00 KG May 28, 2026
    India

    Apixaban

    100 KG Dec 23, 2025
    India

    Apixaban

    5 G Jul 4, 2025
    India

    ISOPROPYL ALCOHOL

    20.00 KG May 27, 2025
    India

    Methanol 

    50.00 KG May 28, 2025
    India

    Cyclopentane  

    40.00 KG May 28, 2025
    Belgium

    Linagliptin API

    200.00 KG Jun 5, 2025
    Belgium

    Silicon dioxide

    100.00 KG Jun 5, 2025
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