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Home > Active Pharmaceutical Ingredients > Circulatory System Drugs > Ezetimibe for Sale > Didu supplies Ezetimibe API >=99%;SCH 60969;zetia/vytorin
Didu supplies Ezetimibe API >=99%;SCH 60969;zetia/vytorin buy - large image1
Didu supplies Ezetimibe API >=99%;SCH 60969;zetia/vytorin buy - image1
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Didu supplies Ezetimibe API >=99%;SCH 60969;zetia/vytorin buy - image3
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Didu supplies Ezetimibe API >=99%;SCH 60969;zetia/vytorin buy - image6

Didu supplies Ezetimibe API >=99%;SCH 60969;zetia/vytorin

6 Inquiries

Unit Price: Get Latest Price
CAS No.:

163222-33-1

Grade:

Medical grade

Content:

99%

Port:

shanghai

Brand:

Dideu

Packaging:

1g/bottle;25kg/drum

Price valid (until):

2024-05-11

Company Type:
Manufactory
Location:
China
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
7 days
Qualification:
Main Products:

Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    High Quality Ezetimibe Producer

    Shop Hexadecylpyridine hydrochloride-Detailed Image 1

    Ezetimibe is a new type of selective cholesterol absorption inhibitor that inhibits the absorption of cholesterol in the small intestine by binding to the membrane protein (relative molecular weight 145X103) on the small intestinal brush like border membrane vesicles, thereby reducing cholesterol levels in serum and liver

    Shop Hexadecylpyridine hydrochloride-Detailed Image 2

    Item

    Standard

    Test Results

    Appearance

    White to off-white powder

    Complies

    Solubility

    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 15 mg/ml)

    Complies

    Individual impurity,%

    0.1

    0.06

    Specific rotation

    -25 ~ -29

    -25.7

    Melting range,

    160 ~ 167

    164 ~ 165

    Loss of drying,%

    0.5

    0.07

    Chloride,%

    0.01

    Complies

    Sulphated ash,%

    0.1

    0.02

    Enantiomer,%

    0.15

    Not Detected

    Diastereomer,%

    0.15

    Not Detected

    Related solvent,ppm

    Methanol  

    3000

    Not Detected

     

    Isopropanol

    5000

    1085

     

    Chlorobenzene

    5000

    Not Detected

    Purity,%

    99.5

    99.94

    Assay,%

    98.0 ~ 102.0(on the dried basis)

    99.1

    Shop Hexadecylpyridine hydrochloride-Detailed Image 3

    Our normal packaging is 25kgs/Drum

    The packaging can be customized. the shipping term can be by sea, by air, and sample or small quantity can be shipped by DHL, FEDEX, EMS and TNT.

    Shop Hexadecylpyridine hydrochloride-Detailed Image 4
    Shop Hexadecylpyridine hydrochloride-Detailed Image 5

    a) Free sample can be supplied.

    b) Guide our clients by professional knowledge and teach them how to use our product after sales.

    c) Accept SGS, BV any other third-party inspection before loading.

    d) High quality best price Guaranteed.

    Shop Hexadecylpyridine hydrochloride-Detailed Image 6
    Shop Hexadecylpyridine hydrochloride-Detailed Image 7

    Why do you choose Dideu as your partner?

    A) High quality can be guaranteed. Dideu since 1975 are reputed chemical manufacturer and are Certified by ISO 9001;2015 and have GMP certification.Free sample can be arranged before shipment and SGS,BV and other third party inspection company are accepted before loading.For regular customers, we accept L/C 180 Days, D/P, D/A payment term. If there is any quality problem after goods arrive. Dideu will do fully payment refund.

    B) Best price can be guaranteed. As Dideu are integrated pharmaceuticals and chemicals producer, the production cost can be controlled and price will be definitely more competitive than China trading companies.

    C) Professional engineers from Dideu will give professional usage guide and services after sales.

    D)Dideu work 7×24 hours and your request will be processed by our professional staff in different shift period.

    Shop Hexadecylpyridine hydrochloride-Detailed Image 8
    Shop Hexadecylpyridine hydrochloride-Detailed Image 9
    Shop Hexadecylpyridine hydrochloride-Detailed Image 10
    Shop Hexadecylpyridine hydrochloride-Detailed Image 11
    Shop Hexadecylpyridine hydrochloride-Detailed Image 12

    Dideu is one of the largest producer for general chemical, pharmaceutical, nutrition additive, natural extracts, agrochemical and Daily-Use Chemical in China and is headquartered in Shaanxi, China. The Dideu Group comprises subsidiaries and joint ventures in more than 10 countries and operates six integrated production sites and 21 other production sites in Europe, Asia, Australia, Americas and Africa. Its headquarters is located in Xi’An,China. Dideu has customers in over 200 countries and supplies products to a wide variety of industries.

     

    At the end of 2014, the company employed more than 13000 people. In 2014, Dideu Group posted sales of 30 billion and income from operations before special items of about 7.5 billion. The company is currently expanding its international activities with a particular focus on Asia countries. Between 1990 and 2005, the company invested 5.2 billion in Asia, for example in sites near Guangxi,Yunnan, Sichuan, Shaanxi China, Mangalore in India,Bangkok, Thailand,Hanoi, Vietnam etc.

     

    Dideu Consist Of Five Industry Chains:

     

    1. 1)Pharmaceutical Industries
    2. 2)Nutrition Additive Industries
    3. 3)Daily-Use Chemical Products Industries & Agrochemicals
    4. 4)Environmental Friendly Chemical And Chemurgy Industries
    5. 5)Petrochemical Industries
    6. 6)General Chemical Industry

     

    At Dideu, we redefine chemistry to make the world better - and have been doing so for 75 years. As one of the world's leading chemical company, we combine economic success with environmental protection and social responsibility. Through science and innovation we enable our customers in nearly every industry to meet the current and future needs of society.

     

    At Dideu, we create chemistry for a sustainable future with science for a better life. Dideu is a Life Science company with a long and glorious history and core competencies in the areas of health care and agriculture. With our innovative products, we are contributing to finding solutions to some of the major challenges of our time. The growing and increasingly aging world population requires improved medical care and an adequate supply of food. Dideu is improving people's quality of life by preventing, alleviating and treating diseases. And we are helping to provide a reliable supply of high quality food, feed and plant based raw materials. We develop new molecules for use in innovative products and solutions to improve health. Our research and development activities are based on a profound understanding of the biochemical processes in living organisms. Our goal is to achieve and sustain leadership positions in our markets, thus creating value for our customers, stockholders and employees. To this end, our strategy is designed to help solve some of the most pressing challenges facing humankind, and by doing this exceptionally well we aim to strengthen the company's earning power.

     

    We are committed to operating sustainably and addressing our social and ethical responsibilities as a corporate citizen, while at the same time respecting the interests of all our stakeholders. Employees with a passion for innovation enjoy excellent development opportunities at Dideu. Exclusive Focus on the Life Science Businesses Following the economic and legal independence of our former Material Science subgroup. Dideu has charted the course for its successful development as a Life Science company. Our Life Science businesses hold leading positions in innovation driven growth markets. Together they make up a strong, attractive and balanced portfolio that is resistant to fluctuations in demand and to potential risks.The previous structure comprising a strategic management holding company and operational subgroups has thus been replaced by an integrated organization under the umbrella of the strong Dideu brand. The company's operations are managed in three divisions Pharmaceuticals, Consumer Health and Crop Science and the Animal Health business unit. The business continues to be supported by the corporate functions, Dideu Business Services and the service company Current, while Technology Services is being integrated into Dideu Group, forming the Engineering and Technology function.

    ECHEMI Editorial Reference
    White SolidEzetimibe is ananti-hyperlipidemic drug used for lowering the plasma cholesterol levels. It is indicated as an adjunctive therapy to diet for the reduction of high-level total-C, LDL-C, and ApoB in patients suffering primary (heterozygous familial and non-familial) hypercholesterolemia. It is also used in combination therapy with HMG-CoA reductase inhibitors.Ezetimibe does not inhibit the cholesterol synthesis in the liver, or increase bile acid excretion.It takes effect throughactin
    Solid
    Ezetimibe is a beta-lactam that is azetidin-2-one which is substituted at 1, 3, and 4 by p-fluorophenyl, 3-(p-fluorophenyl)-3-hydroxypropyl, and 4-hydroxyphenyl groups, respectively (the 3R,3'S,4S enantiomer). It has a role as an anticholesteremic drug, an antilipemic drug and an antimetabolite. It is a member of azetidines, an organofluorine compound and a beta-lactam.|Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption. The discovery and research of this drug began in the early 1990s, after the intravenous administration of radiolabelled ezetimibe in rats revealed that it was being localized within enterocytes of the intestinal villi - this prompted studies investigating the effect of ezetimibe on intestinal cholesterol absorption. Ezetimibe is used as an adjunctive therapy to a healthy diet to lower cholesterol levels in primary hyperlipidemia, mixed hyperlipidemia, homozygous familial hypercholesterolemia (HoFH), and homozygous sitosterolemia (phytosterolemia). Unlike other classes of cholesterol-reducing compounds including statins and bile acid sequestrants, ezetimibe has a distinct mechanism of action involving the sterol transporter Niemann-Pick C1-Like 1 (NPC1L1), and is unique in that it does not affect the absorption of fat-soluble nutrients such as fat-soluble vitamins, triglycerides, or bile acids. In genetically NPC1L1-deficient mice, a 70% reduction in intestinal cholesterol absorption was seen, and these mice were insensitive to ezetimibe treatment - it was determined based on these findings that NPC1L1 plays an essential role in promoting intestinal cholesterol uptake via an ezetimibe-sensitive pathway. By interfering with the intestinal uptake of cholesterol and phytosterols, ezetimibe reduces the delivery of intestinal cholesterol to the liver.|Ezetimibe is a Dietary Cholesterol Absorption Inhibitor. The physiologic effect of ezetimibe is by means of Decreased Cholesterol Absorption.|Ezetimibe is an inhibitor of intestinal cholesterol absorption that is widely used in the therapy of hypercholesterolemia, usually in combination with other agents. Ezetimibe therapy is associated with a low rate of serum aminotransferase elevations and clinically apparent liver injury due to ezetimibe occurs, but is rare.|Ezetimibe is an azetidinone derivative and a cholesterol absorption inhibitor with lipid-lowering activity. Ezetimibe appears to interact physically with cholesterol transporters at the brush border of the small intestine and inhibits the intestinal absorption of cholesterol and related phytosterols. As a result, ezetimibe causes a decrease in the level of blood cholesterol or an increase in the clearance of cholesterol from the bloodstream. Overall, the following effects observed are a reduction of hepatic cholesterol stores and a reduction of total cholesterol, LDL cholesterol, and other triglycerides in the blood.|An azetidine derivative and ANTICHOLESTEREMIC AGENT that inhibits intestinal STEROL absorption. It is used to reduce total CHOLESTEROL; LDL CHOLESTEROL, and APOLIPOPROTEINS B in the treatment of HYPERLIPIDEMIAS.

    Basic Info
    Product Name:

    Ezetimibe

    Other Name:

    2-Azetidinone,1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-,(3R,4S)-;2-Azetidinone,1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-,[3R-[3α(S*),4β]]-;(3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone;Sch 58235;Ezetimibe;(-)-Sch 58235;Zetia;Ezetrol;Ezta;Ezedoc;1-(4-Fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)-hydroxypropyl]-4(S)-(4-hydroxyphenyl)azetidin-2-one;Ezentia

    CAS No.:

    163222-33-1

    Molecular Formula:

    C24H21F2NO3

    InChIKeys:

    InChIKey=OLNTVTPDXPETLC-XPWALMASSA-N

    Molecular Weight:

    409.43

    Exact Mass:

    409.43

    EC Number:

    1308068-626-2

    UNII:

    EOR26LQQ24

    DSSTox ID:

    DTXSID1044223

    NCI Thesaurus Code:

    C47529

    Color/Form:

    White solid

    ATC Code:

    C10B|C10AX09|C - Cardiovascular system

    HScode:

    29337900

    Characteristics
    PSA:

    60.8

    XLogP3:

    4

    Appearance:

    Solid

    Density:

    1.334±0.06 g/cm3(Predicted)

    Melting Point:

    164-166 °C

    Boiling Point:

    654.9±55.0 °C(Predicted)

    Flash Point:

    349.9±31.5 °C

    Refractive Index:

    1.624

    Water Solubility:

    H2O: Insoluble

    Storage Conditions:

    -20°C Freezer

    Vapor Pressure:

    1.5X10-14 mm Hg at 25 deg C (est)

    Specific rotation:

    D22 -33.9° (c = 3 in methanol)

    Henrys Law Constant:

    Henry's Law constant = 4.4X10-18 atm-cu m/mole at 25 °C (est)

    Dissociation Constants:

    pKa1 = 9.73 (phenol) (est)

    Collision Cross Section:

    213.6 Ų [M+Na]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Hazard Identification

    Classification of the substance or mixture

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H410 Very toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P273 Avoid release to the environment.

    Response

    P391 Collect spillage.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

    Location:

    https://www.dideu.com/en/

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7 days

    Total Annual Revenue:

    Above $100 million

    Total Employees:

    Above 1000

    Year of Establishment:

    2016

    Company Certificates
    • Shaanxi Dideu Medichem Co. LtdISO Certificate ISO Certificate
    • Shaanxi Dideu Medichem Co. LtdREACH REACH
    Company Profile
    ">Company Profile
  • Inquiry History
    6 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Ezetimibe

    5.00 KG Jan 22, 2024
    Pakistan

    Ezetimibe

    10 KG Oct 29, 2025
    United States

    Ezetimibe

    10 G Sep 16, 2025
    United States

    Zetia ,Combivent ,Symbicort ,Namenda ,NovoLog FlexPen , Xarelto ,NovoLog ,Humalog , Suboxone ,

    60 MT Oct 12, 2023
    India

    Linagliptin

    5.00 KG Jan 22, 2024
    India

    Febuxostat

    5.00 KG Jan 22, 2024
    Post an enquiry for this product

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