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Supply High Qulity Docetaxel Anhydrous CAS 114977-28-5

Name: Supply High Qulity Docetaxel Anhydrous CAS 114977-28-5
Brand: Custom
SKU: pr2404151005
Price: 240 USD
Availability: InStock

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CAS No.:

114977-28-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Durban

Brand:

Custom

Packaging:

As per customer requirement

Sample Available:

Yes

Price valid (until):

2024-05-14

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Conex Chemicals PTY Ltd

Company Type:

Distributor

Location:

South Africa

Payment Terms:

TT against copy of documents,TT against B/L draft before shipment

Average Lead Time:

60 days

Qualification:

Main Products:

Sodium Lauryl Ether Sulfate,Caustic Soda,Soda Ash,Citric Acid,Calcium Hypochlorite,Oxalic Acid

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Product Details
Seller Information
Inquiry History

Description

Product Detail

Docetaxel (CAS No. 114977-28-5): A Chemotherapeutic Marvel

Enter the realm of docetaxel, a potent chemotherapy agent known by its CAS number 114977-28-5, hailed for its efficacy in combating various cancers. Explore its mechanism of action, clinical applications, and ongoing research endeavors aimed at enhancing its therapeutic potential.

Docetaxel (114977-28-5): Unraveling the Mechanisms of Anticancer Action

Delve into the molecular intricacies of docetaxel, CAS number 114977-28-5, as it targets microtubule dynamics to impede cancer cell proliferation. This description elucidates its role in disrupting mitotic spindle function, inducing apoptosis, and restraining tumor growth across a spectrum of malignancies.

Docetaxel (CAS No. 114977-28-5): Pioneering Precision Oncology

Discover the pioneering role of docetaxel in the era of precision oncology, where tailored treatment approaches optimize therapeutic outcomes. From its integration into multidisciplinary cancer care regimens to its synergy with targeted therapies, this description explores docetaxel's evolving landscape in personalized medicine.

Docetaxel (114977-28-5): A Beacon of Hope in Cancer Therapy

Illuminate the transformative impact of docetaxel on cancer treatment paradigms worldwide. With its CAS number 114977-28-5, this description celebrates docetaxel's role as a beacon of hope, offering survival benefits and improving quality of life for patients battling diverse malignancies.

Docetaxel (CAS No. 114977-28-5) and Beyond: Innovations in Drug Delivery

Explore innovations in docetaxel delivery systems aimed at enhancing efficacy and mitigating adverse effects. From nanoparticle formulations to liposomal encapsulation, this description delves into emerging strategies that harness docetaxel's therapeutic potential while minimizing systemic toxicity.

Docetaxel (114977-28-5): Navigating Adverse Effects and Supportive Care

Navigate the landscape of docetaxel-associated adverse effects and strategies for supportive care. From hematologic toxicities to neuropathies, this description provides insights into mitigating side effects and optimizing patient tolerance during docetaxel-based cancer therapy.

Docetaxel (CAS No. 114977-28-5) in Clinical Practice: From Bench to Bedside

Trace docetaxel's journey from bench to bedside, where translational research and clinical trials have paved the way for its integration into standard cancer care protocols. This description highlights pivotal trials, therapeutic breakthroughs, and ongoing investigations shaping docetaxel's clinical utility.

Docetaxel (114977-28-5): Bridging Research Frontiers in Oncology

Peer into the future of docetaxel research, where genomic insights, biomarker discovery, and immunotherapy combinations hold promise for advancing cancer treatment outcomes. This description explores the cutting-edge research endeavors poised to redefine docetaxel's role in the oncology landscape.

Docetaxel (CAS No. 114977-28-5): Empowering Patients, Inspiring Resilience

Celebrate the resilience and courage of patients navigating docetaxel-based cancer therapy. With its CAS number 114977-28-5, this description honors their journeys, acknowledges their challenges, and underscores the transformative impact of docetaxel in fostering hope and healing amidst adversity.

Items	Specifications
1. Classification	Docetaxel is a chemotherapy medication belonging to the taxane class of drugs.
2. Mechanism of Action	It works by inhibiting microtubule disassembly, disrupting cell division and ultimately leading to cell death.
3. Indications	- Used in the treatment of various cancers, including breast cancer, lung cancer, prostate cancer, and stomach cancer.
4. Administration	Typically administered intravenously (IV) in a clinical setting under the supervision of a healthcare professional.
5. Brand Names	Marketed under various brand names including Taxotere.
6. Side Effects	Common side effects may include hair loss, nausea, vomiting, diarrhea, and decreased blood cell counts.
7. Dosage Forms	Available as a concentrate solution for infusion.
8. Development	Developed by Sanofi-Aventis (now Sanofi) and was approved for medical use in the United States in 1996.
9. Clinical Trials	Extensively studied in clinical trials across various cancer types and treatment regimens to assess its efficacy and safety.
10. Combination Therapy	Often used in combination with other chemotherapy drugs or alongside radiation therapy to enhance treatment outcomes.
11. Resistance	Some cancer cells may develop resistance to Docetaxel over time, necessitating changes in treatment strategies or the addition of other drugs.
12. Pharmacokinetics	Exhibits nonlinear pharmacokinetics, meaning its plasma concentrations do not increase proportionally with dose.
13. Precautions	Requires careful monitoring during administration due to the potential for severe allergic reactions or hypersensitivity reactions.
14. Research Areas	Ongoing research explores novel formulations and delivery methods to improve efficacy, reduce side effects, and overcome resistance mechanisms.
15. Patient Education	Patients receiving Docetaxel should be educated about potential side effects, the importance of adherence to treatment schedules, and strategies for managing symptoms.

Product Detail

ECHEMI Editorial Reference

Docetaxel is an antineoplastic drug by inhibiting microtubule depolymerization, and attenuating of the effects of bcl-2 and bcl-xL gene expression.

Basic Info

Product Name:

Docetaxel

Other Name:

Benzenepropanoic acid,β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-,(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester,(αR,βS)-;Benzenepropanoic acid,β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-,12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester,[2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-;7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete,benzenepropanoic acid deriv.;RP 56976;Docetaxel;Taxotere;N-Debenzoyl-N-tert-butoxycarbonyl-10-deacetyltaxol;Docetaxol;Docetere;Taxotel;SID 530;Duopafei;Docefrez;BIND 014;Miradocetaxel;CKD 810;CRLX 301;ATI 1123;216252-50-5;129522-72-1

CAS No.:

114977-28-5

Molecular Formula:

C43H53NO14

InChIKeys:

InChIKey=ZDZOTLJHXYCWBA-VCVYQWHSSA-N

Molecular Weight:

807.87900

Exact Mass:

807.88

EC Number:

601-339-2

HScode:

2932999099

Categories:

Standard

Characteristics

PSA:

224.45000

XLogP3:

1.6

Appearance:

Off-white Cryst.

Density:

1.37 g/cm3

Melting Point:

232 °C

Boiling Point:

900.5ºC at 760 mmHg

Flash Point:

498.4ºC

Refractive Index:

1.618

Water Solubility:

1.27e-02 g/L

Storage Conditions:

Keep tightly closed. Store at +4ºC.

Vapor Pressure:

5.61X10-27 mm Hg at 25 deg C (est)

See More Docetaxel Properties 

Hazard Identification

Classification of the substance or mixture

Reproductive toxicity, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H361 Suspected of damaging fertility or the unborn child
Prevention	P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Docetaxel Safety Data Sheet 

Seller Information

Business Type:
Distributor

Main Products:
Sodium Lauryl Ether Sulfate,Caustic Soda,Soda Ash,Citric Acid,Calcium Hypochlorite,Oxalic Acid

Location:
13 PROTEA PARK MILKWOOD STREET RANGEVIEW GAUTENG 1739

Payment Terms:
TT against copy of documents,TT against B/L draft before shipment

Average lead Time:
60 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2012

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
Nigeria	Docetaxel	5 G	Apr 13, 2026
Brazil	Docetaxel	1.00 KG	Mar 29, 2025

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