Factory Supply tetramethyl CAS NO 9014-85-1 available at best price

Chemical Identity: Tetramethylammonium Hydroxide (CAS No. 9014-85-1) Description: Tetramethylammonium hydroxide (TMAH) is a quaternary ammonium compound with the chemical formula (CH3)4NOH. It is a strong base and is commercially available in various concentrations and forms, including aqueous solutions and solid pellets.

Physical Properties:

• Appearance: TMAH solutions are typically colorless to pale yellow liquids, while solid pellets may appear as white to off-white crystalline solids.
• Solubility: TMAH is highly soluble in water and miscible with many organic solvents.

Chemical Structure:

• TMAH consists of a tetramethylammonium cation (N(CH3)4+) and a hydroxide anion (OH−). It is a quaternary ammonium salt derived from ammonia by replacing all four hydrogen atoms with methyl groups.

Synthesis Method:

• TMAH can be synthesized by the reaction of trimethylamine (N(CH3)3) with methyl iodide (CH3I) or dimethyl sulfate ((CH3)2SO4), followed by treatment with sodium hydroxide (NaOH) to form the hydroxide salt.

Applications:

• Microelectronics Industry: TMAH is widely used in the microelectronics industry as a developer in the photolithography process for etching silicon wafers. It selectively removes photoresist to create patterns on the wafer surface.
• Chemical Synthesis: TMAH serves as a versatile reagent in organic synthesis for various transformations, including alkylation, deprotection of functional groups, and quaternization reactions.
• Analytical Chemistry: TMAH is employed as a derivatization agent in gas chromatography-mass spectrometry (GC-MS) for the analysis of polar and acidic compounds, enhancing their volatility and detectability.
• Biological Research: TMAH is utilized in biological research for cell lysis, DNA extraction, and protein denaturation due to its strong alkalinity and solubilizing properties.

Safety Considerations:

• TMAH is corrosive and can cause severe burns upon contact with skin and mucous membranes. Inhalation or ingestion of TMAH solutions can lead to respiratory and gastrointestinal irritation.
• Proper handling procedures, including the use of appropriate personal protective equipment (PPE) and ventilation, are essential when working with TMAH to minimize exposure risks.
• Spills should be promptly neutralized with appropriate neutralizing agents and handled according to established safety protocols.

Regulatory Status:

• TMAH is subject to regulatory oversight and may be classified as a hazardous substance in some jurisdictions due to its corrosive properties. Compliance with relevant regulations and safety guidelines is necessary for its safe handling, storage, and transportation.