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Home > Organic Chemistry > Organic Fluorine Compound > 4-Fluoroaniline for Sale > High Quality 4-Fluoroaniline CAS NO (371-40-4) Available For Sale At Cheap Price
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High Quality 4-Fluoroaniline CAS NO (371-40-4) Available For Sale At Cheap Price

6 Inquiries

Unit Price: Get Latest Price
CAS No.:

371-40-4

Grade:

Industrial Grade

Content:

99%

Port:

Durban

Brand:

Custom

Packaging:

As per customer requirement

Price valid (until):

2024-06-03

Company Type:
Distributor
Location:
South Africa
Qualification:
Main Products:

Sodium Lauryl Ether Sulfate,Caustic Soda,Soda Ash,Citric Acid,Calcium Hypochlorite,Oxalic Acid

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Title: Unveiling 4-Fluoroaniline (CAS 371-40-4)

    Introduction: 4-Fluoroaniline, a compound with the chemical formula C6H6FN, is an essential building block in organic synthesis and pharmaceutical chemistry. Its distinct molecular structure, featuring a fluorine atom attached to the para position of an aniline moiety, imparts unique properties that render it valuable in various chemical applications.

    Synthesis: The synthesis of 4-Fluoroaniline typically involves the reaction of aniline with fluorinating agents such as hydrogen fluoride or fluorinating reagents like diethylaminosulfur trifluoride (DAST). Various synthetic routes may be employed, depending on factors such as reagent availability, reaction conditions, and desired yields.

    Physical Properties: 4-Fluoroaniline is commonly observed as a colorless to pale yellow liquid with a characteristic odor. Its physical properties, including melting point, boiling point, and solubility characteristics, play a crucial role in determining its suitability for various applications in laboratory and industrial settings.

    Chemical Reactivity: The presence of the fluorine substituent on the aromatic ring of 4-Fluoroaniline influences its chemical reactivity, allowing it to participate in various organic transformations. It serves as a versatile precursor in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals through substitution, addition, and coupling reactions.

    Industrial Applications: 4-Fluoroaniline finds utility as a key intermediate in the synthesis of pharmaceutical compounds, particularly those used in the production of agrochemicals and pharmaceuticals. Its versatile reactivity and compatibility with other functional groups make it valuable in medicinal chemistry and materials science.

    Environmental Considerations: Responsible handling and disposal practices are essential to mitigate potential environmental risks associated with 4-Fluoroaniline. Adherence to regulatory guidelines and best practices ensures environmental stewardship and minimizes adverse effects on ecosystems.

    Safety Precautions: Safe handling of 4-Fluoroaniline necessitates adherence to stringent safety protocols. Personnel involved in its synthesis, handling, or utilization must utilize appropriate protective equipment and work in well-ventilated environments to minimize potential health hazards associated with exposure.

    Regulatory Compliance: 4-Fluoroaniline may be subject to regulatory oversight by governmental agencies governing its production, transportation, and use. Compliance with applicable regulations is essential to ensure safe practices, protect human health, and uphold environmental responsibility.

    Research and Development: Ongoing research efforts continue to explore the properties and applications of 4-Fluoroaniline, driving advancements in synthetic methodologies and uncovering novel uses in various scientific disciplines and industrial sectors. Future research endeavors are expected to unveil further applications and innovations, enhancing its relevance in the field of chemistry.

    Conclusion: 4-Fluoroaniline stands as a compound of significant importance in organic synthesis and pharmaceutical chemistry. Its unique properties and versatile reactivity make it invaluable in various industrial applications, contributing to advancements in drug discovery, materials science, and beyond. Adherence to safety protocols and environmental regulations ensures its responsible use, fostering sustainability and innovation in the chemical industry.


      Specifications


    Items Specifications
    Chemical Name 4-Fluoroaniline
    CAS Number 371-40-4
    Molecular Formula C6H6FN
    Molecular Weight 111.12 g/mol
    Appearance Colorless to pale yellow liquid
    Melting Point -15 °C
    Boiling Point 182-183 °C
    Density 1.139 g/cm3 at 20 °C
    Solubility Soluble in water and organic solvents
    Vapor Pressure 0.7 mmHg at 25 °C
    Flash Point 82 °C (closed cup)
    Refractive Index 1.557 (20 °C)
    Purity ≥ 99%
    Storage Store in a cool, dry place away from heat and ignition sources
    Hazard Class Flammable liquid, Category 3; Acute toxicity, Category 4








      Product Detail  


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    Basic Info
    Product Name:

    4-Fluoroaniline

    Other Name:

    Benzenamine,4-fluoro-;Aniline,p-fluoro-;4-Fluorobenzenamine;p-Fluoroaniline;4-Fluoroaniline;p-Fluorophenylamine;1-Amino-4-fluorobenzene;4-Fluorophenylamine;NSC 579;4-Fluoro-1-benzenamine

    CAS No.:

    371-40-4

    Molecular Formula:

    C6H6FN

    InChIKeys:

    InChIKey=KRZCOLNOCZKSDF-UHFFFAOYSA-N

    Molecular Weight:

    111.12

    Exact Mass:

    111.12

    BRN:

    742030

    EC Number:

    206-735-5

    UNII:

    60HI1G076Z

    NSC Number:

    579

    UN Number:

    2941

    DSSTox ID:

    DTXSID9022027

    Color/Form:

    Liquid|Pale yellow liquid

    HScode:

    29214210

    Characteristics
    PSA:

    26

    XLogP3:

    1.15

    Appearance:

    Clear pale yellow to red-brown Oily Liquid

    Density:

    1.1725 g/cm3 @ Temp: 20 °C

    Melting Point:

    -1.9 °C

    Boiling Point:

    188 °C

    Flash Point:

    165 °F

    Refractive Index:

    1.548

    Water Solubility:

    H2O: 33 g/L (20 ºC)

    Storage Conditions:

    2-8°C

    Vapor Pressure:

    0.75 mm Hg (1 hectoPa) at 20 deg C

    Toxicity:

    Oral-Rat LD50: 417 mg/kg; Oral-Quail LD50: 100 mg/kg

    Flammability characteristics:

    Open flame is flammable; high heat decomposes toxic fluoride and nitrogen oxide gas

    Henrys Law Constant:

    Henry's Law constant = 6.1X10-6 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    pKa = 4.65 at 25 °C (conjugate acid)

    Experimental Properties:

    UV: 8-41 (Organic Electronic Spectral Data, Phillips et al, John Wiley & Sons, New York) /2-Fluoroaniline/

    Air and Water Reactions:

    Insoluble in water.

    Reactive Group:

    Aryl Halides

    Reactivity Profile:

    Special Hazards of Combustion Products: Irritating and toxic hydrogen fluoride and oxides of nitrogen may form in fires. (USCG, 1999).

    Heat of Combustion:

    780.4 kcal/mol

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    Skin corrosion, Sub-category 1C

    Serious eye damage, Category 1

    Specific target organ toxicity – repeated exposure, Category 2

    Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H302 Harmful if swallowed

    H314 Causes severe skin burns and eye damage

    H373 May cause damage to organs through prolonged or repeated exposure

    H410 Very toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P273 Avoid release to the environment.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

    P363 Wash contaminated clothing before reuse.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P316 Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P317 Get medical help.

    P319 Get medical help if you feel unwell.

    P391 Collect spillage.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    Sodium Lauryl Ether Sulfate,Caustic Soda,Soda Ash,Citric Acid,Calcium Hypochlorite,Oxalic Acid

    Location:

    13 PROTEA PARK MILKWOOD STREET RANGEVIEW GAUTENG 1739

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment

    Average lead Time:

    60

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2012

  • Inquiry History
    6 Inquiries
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