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Home > Biochemical Engineering > Saccharides > Cytidine diphosphate choline for Sale > Cytidine diphosphate choline CAS NO (987-78-0) available for sale
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Cytidine diphosphate choline CAS NO (987-78-0) available for sale

7 Inquiries

Unit Price: Get Latest Price
CAS No.:

987-78-0

Grade:

Industrial Grade

Content:

99%

Port:

Durban

Brand:

Custom

Packaging:

As per customer requirement

Price valid (until):

2024-05-20

Company Type:
Distributor
Location:
South Africa
Qualification:
Main Products:

Sodium Lauryl Ether Sulfate,Caustic Soda,Soda Ash,Citric Acid,Calcium Hypochlorite,Oxalic Acid

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


                        1. Introduction to Cytidine Diphosphate Choline (CDP-Choline, 987-78-0): Cytidine diphosphate choline, also known as CDP-Choline or citicoline, is a crucial intermediate in phospholipid metabolism and a precursor for the synthesis of phosphatidylcholine, a major component of cell membranes. It exhibits various neuroprotective and cognitive-enhancing properties.

                        2. Chemical Composition and Structure: Cytidine diphosphate choline is composed of cytidine, a nucleoside consisting of cytosine linked to ribose, and diphosphocholine, which comprises choline and two phosphate groups. It plays a pivotal role in cellular membrane integrity and neurotransmitter function.

                        3. Biological Function: CDP-Choline serves as a key intermediate in the Kennedy pathway for phosphatidylcholine synthesis, contributing to the structural integrity and fluidity of cellular membranes. Additionally, it participates in the synthesis of acetylcholine, a neurotransmitter involved in cognitive function and memory.

                        4. Neuroprotective Effects: CDP-Choline exhibits neuroprotective properties by enhancing cellular membrane repair, reducing oxidative stress, and promoting the synthesis of neurotrophic factors. It has been studied for its potential therapeutic effects in neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease.

                        5. Cognitive Enhancement: CDP-Choline has been shown to improve cognitive function, memory, and attention in various preclinical and clinical studies. It enhances neurotransmitter synthesis, increases cerebral blood flow, and supports neuronal integrity, leading to improved cognitive performance.

                        6. Stroke Recovery and Brain Injury: CDP-Choline has demonstrated efficacy in promoting recovery and functional outcomes following ischemic stroke and traumatic brain injury. It enhances neuronal repair processes, reduces inflammation, and supports neuroplasticity, facilitating recovery of motor and cognitive functions.

                        7. Pharmacokinetics: Following oral administration, CDP-Choline is rapidly absorbed and metabolized in the body to release cytidine and choline, which are then utilized for phospholipid synthesis and neurotransmitter production. It has good bioavailability and penetrates the blood-brain barrier efficiently.

                        8. Clinical Applications: CDP-Choline is used as a dietary supplement and therapeutic agent in various medical conditions, including cognitive impairment, stroke, traumatic brain injury, and neurodegenerative diseases. It is available in oral and parenteral formulations for clinical use.

                        9. Safety and Side Effects: CDP-Choline is generally well-tolerated with few reported adverse effects. Common side effects may include gastrointestinal discomfort, headache, and insomnia at higher doses. It is considered safe for most individuals when used as directed.

                        10. Future Directions and Research Opportunities: Ongoing research into the mechanisms of action and therapeutic potential of CDP-Choline may lead to further insights into its neuroprotective and cognitive-enhancing effects. Clinical studies exploring its efficacy in various neurological disorders and cognitive deficits are warranted to establish its role in clinical practice.


      Product Detail  


    Items Specifications
    Chemical Formula C14H26N4O11P2
    Molecular Weight 506.32 g/mol
    CAS Number 987-78-0
    Appearance White to off-white powder
    Melting Point Decomposes
    Solubility Soluble in water
    Storage Store at -20°C
    Purity ≥ 98%
    Usage Research chemical
    Stability Stable under recommended storage conditions
    Handling Avoid contact with skin and eyes
    Hazard Statements H315, H319, H335
    Precautionary Statements P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
    Synonyms CDP-Choline, Citicoline
    Applications Used in biochemical research, as a precursor in the synthesis of phospholipids







      Product Detail  


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    Basic Info
    Product Name:

    Cytidine diphosphate choline

    Other Name:

    Cytidine 5′-(trihydrogen diphosphate),P′-[2-(trimethylammonio)ethyl] ester,inner salt;Cytidine 5′-(trihydrogen diphosphate),P′-[2-(trimethylammonio)ethyl] ester,hydroxide,inner salt;Choline,hydroxide,5′-ester with cytidine 5′-(trihydrogen pyrophosphate),inner salt;Cytidine 5′-diphosphate choline;Citicoline;Cytidine diphosphate choline ester;Nicholin;Niticolin;Cereb;Colite;Nicolin;Recofnan;Ensign;Suncholin;CDP-choline;Cytidine diphosphate choline;Cytidine diphosphorylcholine;Cytidine diphosphocholine;Cytidine 5′-diphosphocholine;Cytidine 5′-(cholinyl pyrophosphate);Cytidine choline diphosphate;Cytidine 5′-(choline diphosphate);Choline 5′-cytidine diphosphate;Recognan;Choline cytidine diphosphate;Citicholine;Cytidoline;Citidoline;Somazina;Somazine;Reagin;Neucolis;Difosfocin;Sintoclar;Haocolin;Corenalin;Audes;Rexort;Citifar;Hornbest;Cyscholin;Emicholine F;NSC 122002;Cognizin;1477-47-0;64143-42-6;769081-33-6

    CAS No.:

    987-78-0

    Molecular Formula:

    C14H26N4O11P2

    InChIKeys:

    InChIKey=RZZPDXZPRHQOCG-OJAKKHQRSA-N

    Molecular Weight:

    488.32

    Exact Mass:

    488.107330

    EC Number:

    213-580-7

    DSSTox ID:

    DTXSID9048431

    NCI Thesaurus Code:

    C96743

    ATC Code:

    N - Nervous system

    HScode:

    2942000000

    Categories:

    Saccharides

    Characteristics
    PSA:

    214

    XLogP3:

    -7.07

    Appearance:

    Solid

    Boiling Point:

    851.4°C at 760 mmHg

    Toxicity:

    LD50 in mice, rats (mg/kg): 4600 ±335, 4150 ±370 i.v.; both species 8 g/kg orally (Grau)

    Specific rotation:

    D25 +19.0° (c = 0.86 in H2O)

    Collision Cross Section:

    197.6 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|200.64 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|198.86 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|208.98 Ų [M+Na]+ [CCS Type: DT, Method: stepped-field]|208.41 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|198.3 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|207.8 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|205.9 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|210.2 Ų [M+Na-2H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|207.7 Ų [M-H]-

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    Sodium Lauryl Ether Sulfate,Caustic Soda,Soda Ash,Citric Acid,Calcium Hypochlorite,Oxalic Acid

    Location:

    13 PROTEA PARK MILKWOOD STREET RANGEVIEW GAUTENG 1739

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment

    Average lead Time:

    60

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2012

  • Inquiry History
    7 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    CAS 987-78-0 Citicoline Cdp Choline

    1 KG Oct 27, 2025
    India

    Citicoline Base

    500 KG Jun 27, 2025
    Mexico

    Citicoline

    1 KG Oct 15, 2025
    Poland

    Citicoline Cdp Choline

    50 KG Apr 29, 2024
    Poland

    CITICOLINE, CYTIDINE 5'-DIPHOSPHOCHOLINE,CDP-Coline 98.0% white or almost white crystalline powder

    100 KG Sep 21, 2023
    United States

    Citicoline

    100 G Apr 10, 2026
    Bangladesh

    Butyl Acetate

    1.00 KG Nov 11, 2025
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