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BRADYKININ

Unit Price: Get Latest Price
CAS No.:

58-82-2

Content:

99%

Brand:

CUIKANG

Packaging:

G/bottle,Kg/bag,25kg/barrel

Sample Available:

Yes

Price valid (until):

2025-01-30

Company Type:
Manufactory
Location:
China
Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
45 days
Qualification:
Main Products:

Cosmetics raw materials,Pesticide intermediate,Photoelectric material,pharmaceutical intermediates,Raw materials for food and health products,Polymer materials

  • Product Details

  • Seller Information

  • Description


      Product Detail  


    Bradykinin is a bioactive peptide with a variety of physiological functions. It can cause blood vessels to dilate and enhance capillary permeability, leading to edema and inflammation. In addition, it can also stimulate smooth muscle contraction and affect the activity of adenylate cyclase, which affects the inflammatory response and pain perception. In the medical field, Bradykinin is widely used to treat various inflammatory and pain-related diseases such as dermatitis, arthritis, pain, etc. (Refer to relevant literature)

    Items Specifications






    ECHEMI Editorial Reference
    Bradykinin is an active peptide that is generated by the kallikrein-kinin system. It is a inflammatory mediator and also recognized as a neuromediator and regulator of several vascular and renal functions.
    Solid
    Bradykinin is a linear nonapeptide messenger belonging to the kinin group of proteins, with amino acid sequence RPPGFSPFR. Enzymatically produced from kallidin in the blood, it is a powerful vasodilator that causes smooth muscle contraction, and may mediate inflammation. It has a role as a human blood serum metabolite and a vasodilator agent. It is a tautomer of a bradykinin(2+).|Bradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type 2.|Bradykinin is bradykinin (9 aa, ~1 kDa) is encoded by the human KNG1 gene. This protein is involved in blood pressure regulation and pain receptor stimulation.|A nonapeptide messenger that is enzymatically produced from KALLIDIN in the blood where it is a potent but short-lived agent of arteriolar dilation and increased capillary permeability. Bradykinin is also released from MAST CELLS during asthma attacks, from gut walls as a gastrointestinal vasodilator, from damaged tissues as a pain signal, and may be a neurotransmitter.

    Basic Info
    Product Name:

    BRADYKININ

    Other Name:

    bk;brs640;prs640;C00306;RPPGFSPFR;BRADYZIDE;Callideic;KallidinⅠ;BRADYKININ;CallidinI

    CAS No.:

    58-82-2

    Molecular Formula:

    C50H73N15O11

    InChIKeys:

    QXZGBUJJYSLZLT-FDISYFBBSA-N

    Molecular Weight:

    1060.21

    Exact Mass:

    1059.561401

    EC Number:

    227-781-2

    UNII:

    S8TIM42R2W

    NCI Thesaurus Code:

    C316

    Categories:

    Polypeptide

    Characteristics
    PSA:

    419

    XLogP3:

    -0.82

    Appearance:

    Solid

    Density:

    1.5±0.1 g/cm3

    Melting Point:

    170ºC

    Refractive Index:

    1.693

    Water Solubility:

    soluble to 1 mg/ml in water.

    Storage Conditions:

    −20°C

    Toxicity:

    Abdominal-rat TDL0: 0.00053 mg/kg; intravenous-rat TDL0: 0.000212 mg/kg

    Flammability characteristics:

    Thermal decomposition to release toxic nitrogen oxide gas

    Specific rotation:

    D25 -76.5° (c = 1.37 in 1N acetic acid)

    Collision Cross Section:

    343.33 Ų [M+2H]2+ [CCS Type: DT, Method: stepped-field]|447.61 Ų [M+3H]3+ [CCS Type: DT, Method: stepped-field]|315.25 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|344.2 Ų [M+2H]2+

    Hazard Identification

    Classification of the substance or mixture

    no data available

    GHS label elements, including precautionary statements

    Pictogram(s) no data available
    Signal word

    no data available

    Hazard statement(s)

    no data available

    Precautionary statement(s)
    Prevention

    no data available

    Response

    no data available

    Storage

    no data available

    Disposal

    no data available

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Cosmetics raw materials,Pesticide intermediate,Photoelectric material,pharmaceutical intermediates,Raw materials for food and health products,Polymer materials

    Location:

    D307, Zhuque Square Office Building, No. 14, Chang'an North Road, Beilin District, Xi'an City, Shaanxi Province

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    45 days

    Total Annual Revenue:

    Less than $1 million

    Total Employees:

    11-50

    Year of Establishment:

    2023

    Company Certificates
    • Shaanxi Cuikang Pharmaceutical TechnologISO ISO
    • Shaanxi Cuikang Pharmaceutical TechnologISO ISO
    • Shaanxi Cuikang Pharmaceutical TechnologISO ISO

    Shaanxi Cuikang Pharmaceutical Technology Co., Ltd., founded in January 2023, is a wholly-owned subsidiary of Shaanxi Cuicheng Bio-pharmaceutical Technology Co., Ltd., and a comprehensive innovative enterprise focusing on the research and development, production, sales, import and export trade, technical services and related resource allocation and integration of products in the field of fine chemistry and biochemistry. The company has built a 2700 square meter R&D center in Hanzhong, Shaanxi Province, and has established in-depth and stable cooperative relations with three factories, which can provide one-stop service for domestic and foreign customers from pilot R&D to industrial scale-up production.

    Cuikang Company is an enterprise integrating natural products, fine chemicals, biological fermentation, innovative material research and development, production, sales and technical services. It can provide global customers with a series of products with different specifications and models, such as proportional plant extracts, content plant extracts, synthetic chemical blocks, synthetic pharmaceutical intermediates, active API molecules, fermented pharmaceutical intermediates and APIs, health food, functional food raw materials, veterinary drug raw materials, pharmaceutical innovative materials, laboratory equipment, pharmaceutical machinery and equipment.

    The company adheres to the market demand-oriented, technical innovation as the starting point, product quality as the core, customer service as the foundation, and the enterprise spirit of "professional integrity", and wholeheartedly provides high-quality products and services for customers at home and abroad.


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