Papaverine HCl
GMP 4 Inquiries
58-74-2
Pharmaceutical Grade
99%
PluviaEndo
Customized / Pack & Drum
Yes
2025-11-11
ADDICTION TREATMENT,ANTIDIABETIC,CARDIOVASCULAR,NATURAL EXTRACT,NEUROLOGICAL
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceWhite crystalline powder; obtained asorthorhombic prisms from an alcohol–ethermixture; melts at 147°C (296.6°F); sublimesunder vacuum; insoluble in water; soluble inacetone, glacial acetic acid, and benzene.
Solid
Papaverine is a benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum. It has a role as a vasodilator agent and an antispasmodic drug. It is a benzylisoquinoline alkaloid, a member of isoquinolines and a dimethoxybenzene.|An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.|Papaverine is an opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. As a direct-acting smooth muscle relaxant, papaverine is not closely related to the other opium alkaloids in structure or pharmacological actions; its mechanism of action may involve the non-selective inhibition of phosphodiesterases and direct inhibition of calcium channels. This agent also exhibits antiviral activity against respiratory syncytial virus, cytomegalovirus, and HIV. (NCI04)CertificatesBasic Info-
Product Name:
Papaverine
Other Name:Isoquinoline,1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-;Isoquinoline,6,7-dimethoxy-1-veratryl-;1-[(3,4-Dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline;6,7-Dimethoxy-1-veratrylisoquinoline;Papaverine;Papaverin;6,7-Dimethoxy-1-(3,4-dimethoxybenzyl)isoquinoline;NSC 136630;47446-64-0;85702-67-6
CAS No.:58-74-2
Molecular Formula:C20H21NO4
InChIKeys:InChIKey=XQYZDYMELSJDRZ-UHFFFAOYSA-N
Molecular Weight:375.85
Exact Mass:339.39
BRN:312930
EC Number:200-502-1
UNII:DAA13NKG2Q
NSC Number:136630
DSSTox ID:DTXSID4023418
NCI Thesaurus Code:C726
Color/Form:White prisms from alcohol-diethyl ether; needles from petroleum ether|Triboluminescent, orthorhombic prisms from alcohol + ether|White crystalline powder
ATC Code:A - Alimentary tract and metabolism|G - Genito urinary system and sex hormones
HScode:2933499090
Categories:
Characteristics-
PSA:
49.81000
XLogP3:4.66200
Appearance:white powder
Density:d420 1.337
Melting Point:147.5 °C
Boiling Point:483.2ºC at 760mmHg
Flash Point:172.2ºC
Refractive Index:1.6250 (estimate)
Water Solubility:H2O: 25 mg/mL
Storage Conditions:Store in tight, light-resistant container as defined in the USP-NF. This material should be handled and stored per label instructions to ensure product integrity.
Vapor Pressure:2.33X10-8 mm Hg at 25 deg C (est)
Toxicity:LD50 orl-rat: 325 mg/kg ARZNAD 20,1338,70
PH:Optimal pH for storage of papverine solutions: 2.0-2.8
Henrys Law Constant:Henry's Law constant = 7.51X10-13 atm-cu m/mol at 25 °C (est)
Dissociation Constants:pKa = 8.07 at 25 °C
Collision Cross Section:185.3 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]|186.5 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated]
Experimental Properties:Monoclinic rods from water, mp 220-225 °C. UV max (ethanol) 249-250, 280-282, 311 nm (log E 4.69, 3.80, 3.82). One gram dissolves in about 40 mL water. Soluble in alcohol and chloroform. Practically insoluble in ether. pH of 0.05 molar solution 3.9; pH pf 2% aqueous solution 3.3 /Papverine hydrochloride/|White crystals or crystalline powder. One gram dissolves in about 30 mL of water and 120 mL of alcohol; practically insoluble in ether. ... injection, USP, is clear, colorless to pale-yellow solution /Papaverine hydrochloride/|Light yellow, crystalline powder; slightly soluble in water or alcohol; freely soluble in chloroform, acetone. /Papaverine nitrate/|Hydroxyl radical reaction rate constant = 1.91X10-10 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Papaverine hydrochloride preparations should be stored at a temperature less than 40 deg C, preferably between 15-30 deg C; freezing of the injection should be avoided. ...
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Seller Information
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Business Type:
Manufactory
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Main Products:
ADDICTION TREATMENT,ANTIDIABETIC,CARDIOVASCULAR,NATURAL EXTRACT,NEUROLOGICAL
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Location:
Maslak, MASLAK MAH MASLAK MEYDAN SK BEYBI GIZ PLAZA A, BLOCK NO, 34485 Istanbul, Turkiye
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Payment Terms:
TT against copy of documents,L/C
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Average lead Time:
2 days
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Total Annual Revenue:
Less than $1 million
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Total Employees:
11-50
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Year of Establishment:
2022
Company Certificates-
PLUVIA CONSUMER HEALTH
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Faran Shimi
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Inquiry History4 Inquiries
Country Product Purchase Quantity Date Posted
Thailand
Papaverine
500 G Mar 31, 2026
Moldova
Papaverine
10 KG Jun 25, 2025
India
Papavarine
1 KG Sep 28, 2026
Mexico
Papaverine
100 G Apr 23, 2025 Post an enquiry for this product
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