Antiviral Drugs Acyclovir Powder CAS 59277-89-3 Acycloguanosine
4 Inquiries
59277-89-3
Pharmaceutical Grade
99%
china any port
TNJONE
1kg,25kgor according to customer's detail requirement.
2028-12-31
Semaglutide,Tirzepatide,API,Vitamins,Food Additive
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceAcyclovir, a molecule tailored to inactivate the thymidine kinase of the herpesvirus, is a guanosine analogue antiviral drug. It is a drug for HSV infection by GlaxoSmithKline.IC50 Value: 0.53-0.75 uM [3]Target: HSVin vitro: Acyclovir sensitivity was determined in a plaque-reduction assay in Vero cells. IC50 Values were consistently 2-3 fold lower in B2 compared with the H strain of Vero cells. HSV Type 2 strains were 2-10-fold less sensitive than Type 1 strains [2]. in vivo: two patient
Solid
Acyclovir is an oxopurine that is guanine substituted by a (2-hydroxyethoxy)methyl substituent at position 9. Used in the treatment of viral infections. It has a role as an antiviral drug and an antimetabolite. It is an oxopurine and a member of 2-aminopurines. It derives from a guanine.|Acyclovir is a nucleotide analog antiviral used to treat herpes simplex, Varicella zoster, herpes zoster, herpes labialis, and acute herpetic keratitis. Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old. Acyclovir was granted FDA approval on 29 March 1982.|Acyclovir is a Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor, and Herpes Zoster Virus Nucleoside Analog DNA Polymerase Inhibitor, and Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor. The mechanism of action of acyclovir is as a DNA Polymerase Inhibitor.|Acyclovir is a nucleoside analogue and antiviral agent used in therapy of herpes and varicella-zoster virus infections. Acyclovir has not been associated with clinically apparent liver injury.|Acyclovir is a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus family. After conversion in vivo to the active metabolite acyclovir triphosphate by viral thymidine kinase, acyclovir competitively inhibits viral DNA polymerase by incorporating into the growing viral DNA chain and terminating further polymerization.|A GUANOSINE analog that acts as an antimetabolite. Viruses are especially susceptible. Used especially against herpes.Basic Info-
Product Name:
Acyclovir
Other Name:6H-Purin-6-one,2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-;2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one;Acycloguanosine;9-(2-Hydroxyethoxymethyl)guanine;Acyclovir;Aciclovir;Zovirax;BW 248U;ACV;Gerpevir;Herpevir;Avirase;Virorax;Acicloftal;Cargosil;Vipral;Poviral;Zyclir;Acyclo V;Wellcome 248U;NSC 645011;BioVir I;BioVir II;Virovir;Novirus;Lovir;Rouz-Aciclovir;Zirax;Virless;Virax;Vicclox;Acivir;Axiluowei;2-Amino-9-[(2-hydroxyethoxy)methyl]-6,9-dihydro-3H-purin-6-one;2-Amino-9-(2-hydroxy-ethoxymethyl)-1,9-dihydro-purin-6-one;2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one;2-Amino-9-(2-hydroxy-ethoxymethyl)-3,9-dihydro-purin-6-one;2-Amino-9-[(2-hydroxyethoxy)methyl]-9H-purin-6-ol;2-Amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one
CAS No.:59277-89-3
Molecular Formula:C8H11N5O3
InChIKeys:InChIKey=MKUXAQIIEYXACX-UHFFFAOYSA-N
Molecular Weight:225.2
Exact Mass:225.20
EC Number:261-685-1
UNII:X4HES1O11F
NSC Number:758477|645011
DSSTox ID:DTXSID1022556
NCI Thesaurus Code:C205
Color/Form:Crystals from methanol|Crystals from ethanol|White, crystalline powder
ATC Code:J05AB01|D - Dermatologicals|J - Antiinfectives for systemic use|S - Sensory organs
HScode:2933990090
Categories:
Characteristics-
PSA:
115
XLogP3:-1.6
Appearance:white powder
Density:1.8±0.1 g/cm3
Melting Point:256.5-257 °C
Boiling Point:595°C at 760 mmHg
Flash Point:302.4±32.3 °C
Refractive Index:1.762
Water Solubility:soluble in 1M HCl at 50mg/ml. soluble in water at 0.7mg/ml. Also soluble in DMSO
Storage Conditions:−20°C
Vapor Pressure:5.4X10-15 mm Hg at 25 deg C (est)
Toxicity:Subcutaneous-rat LD50: 620 mg/kg; peritoneal-rat LD50: 860 mg/kg
Flammability characteristics:Flammable; burning releases toxic nitrogen oxide fumes; drug side effects; allergic dermatitis, dreams, fantasy
PKA:2.52and 9.35
Henrys Law Constant:Henry's Law constant = 3.2X10-22 atm-cu m/mol at 25 °C (est)
Dissociation Constants:2.52 and 9.35|pKa1= 2.27; pKa2 = 9.25
Collision Cross Section:146.5 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Experimental Properties:Hydroxyl radical reaction rate constant = 7.94X10-11 cu cm/molecule-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Semaglutide,Tirzepatide,API,Vitamins,Food Additive
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Location:
No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New City, Xi 'an, Shaanxi Province
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
5 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
11-50
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Year of Establishment:
2019
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Inquiry History4 Inquiries
Country Product Purchase Quantity Date Posted 
Indonesia
Acyclovir 59277-89-3
100 G Jul 10, 2025
Indonesia
TGYManufacturer Supply High Purity 99% Acyclovir Powder CAS 59277-89-3
100 G Jun 20, 2025 
India
Chlorhexidine gluconate
500 L Apr 13, 2026 
China
Acuclovir
50 G Nov 11, 2025 Post an enquiry for this product
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