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Home > Active Pharmaceutical Ingredients > Other Chemical Drugs > Terbinafine hydrochloride for Sale > API Terbinafine HCl CAS 78628-80-5 Terbinafine Hydrochloride
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API Terbinafine HCl CAS 78628-80-5 Terbinafine Hydrochloride

15 Inquiries

Unit Price:

$65-80/KG FOB

Get Latest Price
CAS No.:

78628-80-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

china any port

Brand:

TNJONE

Packaging:

1kg,25kgor according to customer's detail requirement.

Price valid (until):

2028-12-30

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Semaglutide,Tirzepatide,API,Vitamins,Food Additive

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    API Terbinafine HCl CAS 78628-80-5 Terbinafine Hydrochloride

    What is Terbinafine HCl   / Terbinafine Hydrochloride ?


    Terbinafine hydrochloride is a white fine crystalline powder that is freely soluble in methan and dichlorome, soluble in ethanol, and slightly soluble in water. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway. Because terbinafine prevents conversion ofsqualene to lanosterol, ergosterol cannot be synthesized. This is thought to change cell membrane permeability, causing fungal cell lysis.

    Terbinafine·HCl a member of the allyl class of antifungals, has been found to be a specific inhibitor of ergosterol synthesis via squalene epoxidase inhibition. Squalene epoxidase is an enzyme released by the dermatophyte fungi to break down Squalene, which interferes with cell membrane function and wall synthesis.


    Items Specifications
    Product Name Terbinafine HCl   / Terbinafine Hydrochloride
    Cas No 78628-80-5
    Einecs 616-640-4
    MF C21H26ClN
    MW 327.89
    Melting Point  204-208°C
    Appearance White powder
    Shelf Life 2 Years When Properly Stored
    Storage Keep in a cool, dry, dark location in a tightly sealed container or cylinder.


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    Application:


    Terbinafine hydrochloride has a fungicidal effect on skin fungi and an inhibitory effect on Candida albicans. It is suitable for skin and nail infections caused by superficial fungi, such as ringworm, ringworm of the body, ringworm of the femur, ringworm of the feet, ringworm of the nail and Candida albicans infection of the skin caused by Trichophyton rubrum, Microsporum canis and Flocculus epidermidis.

    1. Terbinafine Hcl is mainly effective on the dermatophyte group of fungi.
    2. As a 1% cream or powder, it is used topically for superficial skin infections such as jock itch (tinea cruris), athlete's foot (tinea pedis), and other types of ringworm (tinea corporis). Terbinafine cream works in about half the time required by other antifungals.
    3. Oral 250mg tablets are often prescribed for the treatment of onychomycosis, a fungal nail infection, typically by a dermatophyte or Candida species. Fungal nail infections are located deep under the nail in the cuticle to which topically applied treatments are unable to penetrate in sufficient amounts. The tablets may, rarely, cause hepatotoxicity, so patients are warned of this and may be monitored with liver function tests. Alternatives to oral administration have been studied. 
    4. Terbinafine may induce or exacerbate subacute cutaneous lupus erythematosus. Persons with lupus erythematosus should first discuss possible risks with their doctor before initiation of therapy.

    Company Information 


    Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital of Xi 'an, is committed to pharmaceutical raw materials, kill varieties, food and feed additives, chemical reagents, plant extracts and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products. Our company after careful planning, hard study, gradually formed a complete service system, based on the domestic and foreign raw materials market special development. Make the raw materials industry bigger and stronger, and serve the vast number of new and old customers. With "world peace and health" as its responsibility, the company adheres to the service concept of "meeting all requirements of customers for products", and guarantees the service principle of "providing qualified products", so that you can get the "God-like" noble shopping enjoyment. Our company has more than 500 kinds of raw materials inventory at any time to meet the various needs of customers for products. The company's products all comply with the relevant national regulations, from the smallest packaging to tons of goods are available. Is your choice of raw materials the best partner.


    Shaanxi TNJONE Pharmaceutical Technology Co., Ltd. is willing to rely on the rapid development of e-commerce and national policy support of the good environment background, nesting, welcome people from all walks of life to visit our company, exchange, and seek common development, looking forward to sharing with you, win-win, to realize the dream.


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    FAQ

    1.How to get in touch with us?

    You can chat with us by Trademanager,WhatsApp or simply giving us an email, a phone call. All our contacts information can be found from our website.

     

    2.Are you a manufacturer or trade company?

    We are a professional manufacturer.

     

    3.Can I get a sample?

    Yes, free sample can be provided, but shipping cost is covered by your side.

     

    4.What's your MOQ?

    It is based on the different product. Some are 1g while some are 1 kg. Please be free to consult our salesman.

     

    5.When can I get the quotation?
    We usually quote within 1 hours after we get your inquiry. If it's a urgent order you can call us or mention it in your email subject, and we can take it as priority.

     

    6.Is there any discount?
    Yes, some products are applied for discount, but it depends on the quantity.

     

    7.Can you do OEM for me?
    Yes,we accept OEM orders, just contact us and give us your requirement. We will offer you a reasonable price and make samples ASAP.

    Basic Info
    Product Name:

    Terbinafine hydrochloride

    Other Name:

    1-Naphthalenemethanamine,N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-,hydrochloride (1:1);1-Naphthalenemethanamine,N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-,hydrochloride,(E)-;1-Naphthalenemethanamine,N-[(2E)-6,6-dimethyl-2-hepten-4-ynyl]-N-methyl-,hydrochloride;Terbinafine hydrochloride;Terbina;Lamisil;Bramazil;Bramizil;Muzonal;Terbine;Lamisil Once

    CAS No.:

    78628-80-5

    Molecular Formula:

    C21H25N.ClH

    InChIKeys:

    InChIKey=BWMISRWJRUSYEX-SZKNIZGXSA-N

    Molecular Weight:

    327.89100

    Exact Mass:

    327.17500

    EC Number:

    616-640-4

    HScode:

    2921499090

    Categories:

    Other Chemical Drugs

    Characteristics
    PSA:

    3.24000

    XLogP3:

    5.67930

    Appearance:

    Crystalline powder

    Density:

    1.007g/cm3

    Melting Point:

    205 °C @ Solvent: Isopropanol

    Boiling Point:

    417.9ºC at 760 mmHg

    Flash Point:

    183.7ºC

    Refractive Index:

    1.586

    Storage Conditions:

    -20ºC Freezer

    Toxicity:

    LD50 in mice, rats (mg/kg): 4000, 4000 orally; 393, 213 i.v. (Ganzinger)

    Hazard Identification

    Classification of the substance or mixture

    Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H400 Very toxic to aquatic life

    H410 Very toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P273 Avoid release to the environment.

    Response

    P391 Collect spillage.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Semaglutide,Tirzepatide,API,Vitamins,Food Additive

    Location:

    No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New City, Xi 'an, Shaanxi Province

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    5

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2019

    Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital Xi 'an, is committed to the peptide industry, pharmaceutical raw materials, food and feed additives, veterinary drugs and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products, "world peace and health" as its responsibility, the company adhering to the "meet all customer requirements for products" as the service concept, Guarantee "provide qualified products" as the service principle, so that you get "God-like" noble shopping enjoyment. Our company has more than 1000 kinds of polypeptides, raw materials inventory, at any time to meet the various needs of customers for products. Is your best partner.
  • Inquiry History
    15 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Terbinafine HydrochlorideUSP

    75.00 KG Dec 4, 2025
    Israel

    terbinafibe hydrochloride

    1 KG Dec 13, 2023
    India

    Terbinafine HCl

    10 MT Jun 30, 2026
    India

    Terbinafine HCl

    20 TON May 14, 2025
    United States

    Terbinafine Hydrochloride

    1 KG Jun 17, 2024
    Germany

    Terbinafine Hydrochloride

    1 KG May 7, 2024
    United States

    Terbinafine Hydrochloride

    1 KG Jan 16, 2024
    United States

    Terbinafine HCL

    5 MT Jan 5, 2024
    Hongkong, China

    Terbinafine hcl

    190 MT Jun 5, 2026
    United States

    Terbinafine Hydrochloride

    Aug 26, 2024
    United Kingdom

    Terbinafine Hydrochloride

    1 KG May 20, 2024
    Pakistan

    TERBINAFINE HCL

    100 KG Jan 9, 2026
    India

    Terbinafine HCl

    5 MT Sep 2, 2025
    Pakistan

    Terbinafine HCL

    300.00 G Jul 3, 2025
    Pakistan

    Terbinafine HCl

    100.00 KG Dec 31, 2024
    Post an enquiry for this product
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