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CAS 117704-25-3 Antiparasitics Raw 99% Doramectin Powder

Name: CAS 117704-25-3 Antiparasitics Raw 99% Doramectin Powder
Brand: TNJONE
SKU: pr2407011086
Price: 30 USD
Availability: InStock

25 Inquiries

Unit Price:

$30-35/KG FOB

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CAS No.:

117704-25-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

China any port

Brand:

TNJONE

Packaging:

1kg,25kgor according to customer's detail requirement.

Price valid (until):

2027-10-25

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Shaanxi TNJONE Pharmaceutical Co., Ltd

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Semaglutide,Tirzepatide,API,Vitamins,Food Additive

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Product Description
Seller Information
Inquiry History

Description

CAS 117704-25-3 Antiparasitics Raw 99% Doramectin Powder

What is Doramectin?

Doramectin is obtained by fermenting a new strain of Streptomyce avermitilis. It is a broad-spectrum antiparasitic drug. It has a good repellent effect on internal and external parasites, especially some nematodes (roundworms) and arthropods, but it is not effective on tapeworms, flukes and protozoa. Its mechanism of action is mainly to increase the release of the inhibitory transmitter γ-aminobutyric acid (GABA) of the worm, thereby blocking the transmission of neural signals, causing muscle cells to lose their ability to contract, and causing the worm to die. The mammalian peripheral neurotransmitter is acetylcholine and is not affected by doramectin. Doramectin does not easily penetrate the blood-brain barrier, has minimal damage to the central nervous system, and is safer for livestock.

Items	Specifications
Product Name	Doramectin
Cas No	117704-25-3
Einecs	601-490-4
MF	C50H74O14
MW	899.11
Melting Point	116-119°C (dec.) (lit.)
Boiling Point	967.4±65.0 °C(Predicted)
Density	1.25±0.1 g/cm3(Predicted)
Appearance	White powder
Shelf Life	2 Years When Properly Stored
Storage	Keep in a cool, dry, dark location in a tightly sealed container or cylinder.

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Specification

Item	Specifications	Results
Appearance	White or off white crystalline powder	White crystalline powder
Identification	1,IR spectrum is consistent with CRS	Conforms
Identification	2,The retention time of the main peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the standard preparation. As obtained in the Assay.	Conforms
Clarity & color	Colorless and clear	Colorless and clear
Fluorides	≥12.0%	12.0%
Related substance	Individual impurity ≤0.5%	0.25%
Related substance	Total impurities ≤1.0%	0.63%
Loss on drying	≤0.5%	0.12%
Residue on ignition	≤0.1%	0.06%
Heavy metals	Not more than 10ppm	Conform
Assay (HPLC)	Not less than 98.0%	99.2%
Conclusion	The results conforms with Import Veterinary Drug standards

Function & Application
It is used for the treatment and control of internal parasitosis (gastrointestinal and pulmonary nematodes), ticks and mange (and other ectoparasites). Doramectin is a derivative of ivermectin. Its spectrum includes:Haemonchus spp., Ostertagia spp., Trichostrongylusspp., Cooperia spp., Oesophagostomum spp., Dictyocaulus viviparus, Dermatobia hominis, Boophilus microplus, Psoroptes bovis, among many other internal and external parasites. It is available in 2 dosage forms: as aninjection and as a 5 mg/ml topical solution.
Doramectin is effective against the major parasitic roundworms: gastrointestinal and pulmonary. It is also effecive against most mites and lice species, and against numerous myiases (e.g. those caused by screwworm flies, bot flies and warble flies) usually regardless of the delivery form As all macrocyclic lactone doramectin acts as agonist of the GABA (gamma-aminobutyric acid) neurotransmitter in nerve cells and also binds to glutamate-gated chloride channels in nerve and muscle cells of invertebrates. In both cases it blocks the transmission of neuronal signals of the parasites, which are either paralyzed and expelled out of the body, or they starve. It also affects the reproduction of some parasites by diminishing oviposition or inducing an abnormal oogenesis.

Company Information

Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital of Xi 'an, is committed to pharmaceutical raw materials, kill varieties, food and feed additives, chemical reagents, plant extracts and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products. Our company after careful planning, hard study, gradually formed a complete service system, based on the domestic and foreign raw materials market special development. Make the raw materials industry bigger and stronger, and serve the vast number of new and old customers. With "world peace and health" as its responsibility, the company adheres to the service concept of "meeting all requirements of customers for products", and guarantees the service principle of "providing qualified products", so that you can get the "God-like" noble shopping enjoyment. Our company has more than 500 kinds of raw materials inventory at any time to meet the various needs of customers for products. The company's products all comply with the relevant national regulations, from the smallest packaging to tons of goods are available. Is your choice of raw materials the best partner.

Shaanxi TNJONE Pharmaceutical Technology Co., Ltd. is willing to rely on the rapid development of e-commerce and national policy support of the good environment background, nesting, welcome people from all walks of life to visit our company, exchange, and seek common development, looking forward to sharing with you, win-win, to realize the dream.

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FAQ

1.How to get in touch with us?

You can chat with us by Trademanager,WhatsApp or simply giving us an email, a phone call. All our contacts information can be found from our website.

2.Are you a manufacturer or trade company?

We are a professional manufacturer.

3.Can I get a sample?

Yes, free sample can be provided, but shipping cost is covered by your side.

4.What's your MOQ?

It is based on the different product. Some are 1g while some are 1 kg. Please be free to consult our salesman.

5.When can I get the quotation?
We usually quote within 1 hours after we get your inquiry. If it's a urgent order you can call us or mention it in your email subject, and we can take it as priority.

6.Is there any discount?
Yes, some products are applied for discount, but it depends on the quantity.

7.Can you do OEM for me?
Yes,we accept OEM orders, just contact us and give us your requirement. We will offer you a reasonable price and make samples ASAP.

ECHEMI Editorial Reference

So the effect of doramectin to drive and to kill the parasites is stronger than ivermectin, and it can be effective to prevent the parasite reinfection.

Basic Info

Product Name:

Doramectin

Other Name:

Avermectin A1a,25-cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)-;Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2′-[2H]pyran],avermectin A1a deriv.;25-Cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)avermectin A1a;Doramectin;UK 67994;25-Cyclohexylavermectin B1;Dectomax;L 701023;Doramectin A1a;Treo ACE;Treo Ace Injetavel;157544-18-8

CAS No.:

117704-25-3

Molecular Formula:

C50H74O14

InChIKeys:

InChIKey=QLFZZSKTJWDQOS-YDBLARSUSA-N

Molecular Weight:

899.11

Exact Mass:

899.11

EC Number:

1308068-626-2

HScode:

29419090

Categories:

Veterinary Raw Materials

Characteristics

PSA:

170

XLogP3:

5.91160

Appearance:

white

Density:

1.25±0.1 g/cm3(Predicted)

Melting Point:

116-119 °C

Boiling Point:

967.4±65.0 °C(Predicted)

Flash Point:

274.4±27.8 °C

Refractive Index:

1.580

Water Solubility:

methanol: soluble

Storage Conditions:

0-6°C

Vapor Pressure:

0mmHg at 25°C

See More Doramectin Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Reproductive toxicity, Category 2

Reproductive toxicity, Additional category for effects on or via lactation

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H361 Suspected of damaging fertility or the unborn child H362 May cause harm to breast-fed children H400 Very toxic to aquatic life H410 Very toxic to aquatic life with long lasting effects
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P260 Do not breathe dust/fume/gas/mist/vapours/spray. P263 Avoid contact during pregnancy and while nursing. P273 Avoid release to the environment.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P318 IF exposed or concerned, get medical advice. P391 Collect spillage.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Doramectin Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Semaglutide,Tirzepatide,API,Vitamins,Food Additive

Location:
No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New City, Xi 'an, Shaanxi Province

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
5

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2019

Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital Xi 'an, is committed to the peptide industry, pharmaceutical raw materials, food and feed additives, veterinary drugs and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products, "world peace and health" as its responsibility, the company adhering to the "meet all customer requirements for products" as the service concept, Guarantee "provide qualified products" as the service principle, so that you get "God-like" noble shopping enjoyment. Our company has more than 1000 kinds of polypeptides, raw materials inventory, at any time to meet the various needs of customers for products. Is your best partner.

Inquiry History

25 Inquiries

Country	Product	Purchase Quantity	Date Posted
Paraguay	Doramectina	60 KG	Oct 27, 2025
Ecuador	DORAMECTINA	100 KG	May 20, 2025
Ecuador	DORAMECTINA	5 KG	Mar 14, 2024
Russia	Doramectin	0.25 KG	Jul 30, 2024
Ecuador	DORAMECTINA	5 KG	Mar 7, 2024
Paraguay	Sodium lauryl ether sulphate	4000 KG	Feb 25, 2026
Paraguay	Lanolin	100 KG	Nov 4, 2025
Paraguay	Choline chloride	200 KG	Oct 27, 2025
Paraguay	Cefalexin compacted micronized	200 KG	Oct 27, 2025
Paraguay	Mebendazole	100 KG	Nov 4, 2025
Paraguay	Azepromacine maleate	10 KG	Oct 27, 2025
Paraguay	Cypermethrin	3000 KG	Feb 25, 2026
Paraguay	Fenthion	400 KG	Mar 13, 2026
Paraguay	N-Methil-2-pyrrolidone	1000 KG	Feb 25, 2026
Paraguay	Benzidamine hidrochloride	300 KG	Feb 25, 2026
Paraguay	Streptomycin sulfate	1500 BOU	May 22, 2026
Paraguay	Medroxyprogesterone acetate micronized	150 KG	May 22, 2026
Paraguay	Penicillin G sodium	2200 BOU	Mar 24, 2026
Paraguay	Cypermethrin	300 KG	Mar 24, 2026
Paraguay	D(+)-Glucose	10000 KG	Aug 28, 2026

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