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China 99% Doxofylline CAS 69975-86-6 Pharmaceutical Raw Materials

Name: China 99% Doxofylline CAS 69975-86-6 Pharmaceutical Raw Materials
Brand: Airuike
SKU: pr2407042206
Price: 1 USD
Availability: InStock

4 Inquiries

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CAS No.:

69975-86-6

Grade:

Pharmaceutical Grade

Content:

Port:

qingdao

Brand:

Airuike

Packaging:

100g;1kg;25g

Price valid (until):

2024-08-04

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Shandong Airuike Chemical Co., Ltd.

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,D/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

15 days

Qualification:

Main Products:

api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Product description:Crystal, melting point 144-145.5°C. Soluble in water, benzene, hot or hot ethanol, almost insoluble in ether.

Items	Specifications
Melting point	144-146°C
Boiling point	409.46°C (rough estimate)
density	1.2896 (rough estimate)
refractive index	1.6000 (estimate)
RTECS	XH5135000
storage temp.	Inert atmosphere,2-8°C
pka	0.42±0.70(Predicted)
Water Solubility	Soluble
Merck	14,3438

Shop Nice Price CAS 8002-31-1 Buy Cocoabutter Supplier Seller Manufacturer Factory-Detailed Image 1

ECHEMI Editorial Reference

Doxofylline is an antagonist of adenosine A1 receptor which also inhibits phosphodiesterase IV.
Doxofylline is an oxopurine that is a derivative of xanthine, methylated at N-1 and N-3 and carrying a 1,3-dioxolan-2-ylmethyl group at N-7, used in the treatment of asthma. It has a role as a bronchodilator agent, an antitussive and an anti-asthmatic drug. It derives from a 7H-xanthine.|Doxofylline is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with significantly fewer side effects in animal and human studies. In contrast with other xanthine derivatives, doxofylline does not significantly bind to adenosine alpha-1 or alpha-2 receptors and lacks stimulating effects. Decreased affinity for adenosine receptors may account for the better safety profile of doxofylline compared to theophylline. Unlike theophylline, doxofylline does not affect calcium influx and does not antagonize the actions of calcium channel blockers which could explain reduced cardiac adverse reactions associated with the drug. The anti-asthmatic effects of doxophylline are mediated by other mechanisms, primarily through inhibiting the activities of the phosphodiesterase (PDE) enzyme.

Basic Info

Product Name:

Doxofylline

Other Name:

1H-Purine-2,6-dione,7-(1,3-dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-;Theophylline,7-(1,3-dioxolan-2-ylmethyl)-;7-(1,3-Dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione;2-(7′-Theophyllinemethyl)-1,3-dioxolane;ABC 1213;Dioxyfilline;Doxophylline;Doxofylline;Ansimar;Maxivent;ABC 12/3;Ventax;Synasma

CAS No.:

69975-86-6

Molecular Formula:

C11H14N4O4

InChIKeys:

InChIKey=HWXIGFIVGWUZAO-UHFFFAOYSA-N

Molecular Weight:

266.25

Exact Mass:

266.25

EC Number:

274-239-6

UNII:

MPM23GMO7Z

NSC Number:

759645

DSSTox ID:

DTXSID7022968

ATC Code:

R - Respiratory system

HScode:

29399990

Categories:

Respiratory Drugs

Characteristics

PSA:

76.9

XLogP3:

-0.70

Density:

1.6±0.1 g/cm3

Melting Point:

144-145.5 °C

Boiling Point:

505.2±53.0 °C at 760 mmHg

Flash Point:

259.3±30.9 °C

Refractive Index:

1.700

Water Solubility:

H2O: soluble

Toxicity:

LD50 in mice (mg/kg): 841 orally; 215.6 i.v.; in rats: 1022.4 orally, 445 i.p. (Franzone)

See More Doxofylline Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin irritation, Category 2

Eye irritation, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H315 Causes skin irritation H319 Causes serious eye irritation
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Doxofylline Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals

Location:
Huangdao District, Qingdao City, Shandong Province (formerly Room 606-2, Building 1, No. 10 Beijing Road, Jiaonan City)

Payment Terms:
TT against copy of documents,D/P,D/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
51-100

Year of Establishment:
2023

Company Certificates
- Credit rating certificate
- Hazardous Chemicals Business License
Company Profile
Foucsing on chemical industry,Shandong Airuike Chemical Co., LTD was established in the year 2013 and since then devoted all its efforts on how to bring best products and services to every customer,with intergrated sources and creative minds.
We are offering the market with Organic chemicals, Inorganic chemicals, Organic intermediates and water treatment products.
In construction industry,our furan resin product is high-light for metal casting as well as anticorrosion projecting for new chemical plant construction and repairing works.
Your consistent trust is our infinite power to move forward. Shandong Airuike Chemical Co., LTD never stop its step on technical researching,quality supervising,effective logistic arranging and on time services to fully satisfy customers requests. We also extended our product range by close cooperating with famous producers all around China,around the world.
By now we have established business relationship with more than 200 customers around the world.
Like our company motto says,”Innovation as power,quality as life,be honest people practical development”,Shandong Airuike Chemical Co., LTD team always put sincerity and honesty in the first place and in return customers trust us and develop win-win cooperation betwwen each other.
You’re always welcomed to contact us and share your needs,let us give you an unique satisfying for our business cooperation together.

Inquiry History

4 Inquiries

Country	Product	Purchase Quantity	Date Posted
Bangladesh	Doxophylline	1 KG	Mar 4, 2026
Bangladesh	Doxofylline	1 MT	Sep 2, 2026
Bangladesh	Doxophylline	100 KG	Mar 4, 2026
Pakistan	Doxofylline Sodium	150 KG	Jul 16, 2025

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China 99% Doxofylline CAS 69975-86-6 Pharmaceutical Raw Materials

Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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