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Home > Active Pharmaceutical Ingredients > Other Chemical Drugs > Clindamycin for Sale > API Antibiotics CAS 18323-44-9 Clindamycin Powder
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API Antibiotics CAS 18323-44-9 Clindamycin Powder

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CAS No.:

18323-44-9

Grade:

Pharmaceutical Grade

Content:

99%

Port:

china any port

Brand:

TNJONE

Packaging:

1kg,25kg or according to customer's detail requirement.

Price valid (until):

2025-10-31

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Semaglutide,Tirzepatide,API,Vitamins,Food Additive

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    API Antibiotics CAS 18323-44-9 Clindamycin Powder

    What is Clindamycin  ?


    Clindamycin is an oral protein synthesis inhibitory agent that has the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla).

    Items Specifications
    Product name Clindamycin 
    CAS No. 18323-44-9
    MF C18H33ClN2O5S
    MW 424.98
    EINECS.No 242-209-1
    Boiling Point  134°C (rough estimate)
    Density 1.1184 (rough estimate)
    Appearance white powder
    Shelf Life 2 Years When Properly Stored
    Storage Keep in a cool, dry, dark location in a tightly sealed container or cylinder.


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    Specification 

    Test items Specifications Results
    Characters White or practically white,crystalline powder White crystalline powder
    Identification IR Conform Conform
    Solubility Freely soluble in water, in dimethylformamide, and in methanol;soluble in alcohol;practically insoluble in acetone Conform
    Crystallinity Conform  
    PH 3.0~5.5 3.9
    Water 3.0%~6.0% 4.00%
    Related compounds

    ≤2.0% clindamycin B

    ≤4.0% 7-epiclindamycin

    ≤1.0% any other individual related compound

    ≤6.0% total of all related compound

    Conform
    Residual solvents

    Acetone ≤5000ppm

    N,N-Dimethylformamide≤880ppm

    Chloroform≤60ppm

    Conform
    Assay Not less than 800μg of clindamycin (C18H33ClN2O5S)per mg 862 μg/mg


    Function
    Clindamycin is used primarily to treat anaerobic infections caused by susceptible anaerobic bacteria, including dental infections, and infections of the respiratory tract, skin, and soft tissue, and peritonitis. In people with hypersensitivity to penicillins, clindamycin may be used to treat infections caused by susceptible aerobic bacteria, as well. It is also used to treat bone and joint infections, particularly those caused by Staphylococcus aureus. Topical application of clindamycin phosphate can be used to treat mild to moderate acne.

    Application 

    The use of clindamycin in conjunction with benzoyl peroxide is more effective in the treatment of acne than the use of either product by itself.


    When testing a Gram-positive culture for sensitivity to clindamycin, it is common to perform a "D-Test" to determine if there is a macrolide-resistant subpopulation of bacteria present.

    Given with chloroquine or quinine, clindamycin is effective and well tolerated in treating Plasmodium falciparum malaria; The latter combination is particularly useful for children, and is the treatment of choice for pregnant women who become infected in areas where resistance to chloroquine is common.

    Clindamycin may be useful in skin and soft tissue infections caused by methicillin-resistant Staphylococcus aureus (MRSA).

    The combination of clindamycin and quinine is the standard treatment for severe babesiosis.

    Clindamycin may also be used to treat toxoplasmosis, and, in combination with primaquine, is effective in treating mild to moderate Pneumocystis jirovecii pneumonia.

    The veterinary uses of clindamycin are quite similar to its human indications, and include treatment of osteomyelitis, skin infections, and toxoplasmosis, for which it is the preferred drug in dogs and cats. Toxoplasmosis rarely causes symptoms in cats, but can do so in very young or immunocompromised kittens and cats.

    Company Information 


    Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital of Xi 'an, is committed to pharmaceutical raw materials, kill varieties, food and feed additives, chemical reagents, plant extracts and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products. Our company after careful planning, hard study, gradually formed a complete service system, based on the domestic and foreign raw materials market special development. Make the raw materials industry bigger and stronger, and serve the vast number of new and old customers. With "world peace and health" as its responsibility, the company adheres to the service concept of "meeting all requirements of customers for products", and guarantees the service principle of "providing qualified products", so that you can get the "God-like" noble shopping enjoyment. Our company has more than 500 kinds of raw materials inventory at any time to meet the various needs of customers for products. The company's products all comply with the relevant national regulations, from the smallest packaging to tons of goods are available. Is your choice of raw materials the best partner.


    Shaanxi TNJONE Pharmaceutical Technology Co., Ltd. is willing to rely on the rapid development of e-commerce and national policy support of the good environment background, nesting, welcome people from all walks of life to visit our company, exchange, and seek common development, looking forward to sharing with you, win-win, to realize the dream.


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    FAQ

    1.How to get in touch with us?

    You can chat with us by Trademanager,WhatsApp or simply giving us an email, a phone call. All our contacts information can be found from our website.

     

    2.Are you a manufacturer or trade company?

    We are a professional manufacturer.

     

    3.Can I get a sample?

    Yes, free sample can be provided, but shipping cost is covered by your side.

     

    4.What's your MOQ?

    It is based on the different product. Some are 1g while some are 1 kg. Please be free to consult our salesman.

     

    5.When can I get the quotation?
    We usually quote within 1 hours after we get your inquiry. If it's a urgent order you can call us or mention it in your email subject, and we can take it as priority.

     

    6.Is there any discount?
    Yes, some products are applied for discount, but it depends on the quantity.

     

    7.Can you do OEM for me?
    Yes,we accept OEM orders, just contact us and give us your requirement. We will offer you a reasonable price and make samples ASAP.

    Basic Info
    Product Name:

    Clindamycin

    Other Name:

    L-threo-α-D-galacto-Octopyranoside,methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-;L-threo-D-galacto-Octopyranoside,methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-,trans- α-;L-threo-α-D-galacto-Octopyranoside,methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-,(2S-trans)-;Methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside;Clindamycin;Dalacin C;7-Chloro-7-deoxylincomycin;Clinimycin;7-Chlorolincomycin;Cleocin;7(S)-Chloro-7-deoxylincomycin;Sobelin;7-Deoxy-7(S)-chlorolincomycin;7-CDL;U 21251;Chlolincocin;Antirobe;Dalacine;Klimicin;ClindaDerm;Klindan 300;Dalacin V;Clincin;Clindam;13441-63-9;16669-21-9;24620-78-8;24696-19-3;1376624-06-4;1376758-11-0

    CAS No.:

    18323-44-9

    Molecular Formula:

    C18H33ClN2O5S

    InChIKeys:

    InChIKey=KDLRVYVGXIQJDK-AWPVFWJPSA-N

    Molecular Weight:

    424.98

    Exact Mass:

    424.98

    EC Number:

    242-209-1

    DSSTox ID:

    DTXSID2022836

    Color/Form:

    Yellow, amorphous solid

    ATC Code:

    D - Dermatologicals|G - Genito urinary system and sex hormones|J - Antiinfectives for systemic use

    Categories:

    Other Chemical Drugs

    Characteristics
    PSA:

    127.56000

    XLogP3:

    1.83

    Density:

    1.3±0.1 g/cm3

    Melting Point:

    141 - 143ºC

    Boiling Point:

    628.1±55.0 °C at 760 mmHg

    Flash Point:

    333.6±31.5 °C

    Refractive Index:

    1.574

    Water Solubility:

    >63.7 [ug/mL]|In water, 30.61 mg/L at 25 °C (est)

    Storage Conditions:

    Store in tight container as defined in the USP-NF. This material should be handled and stored per label instructions to ensure product integrity.|Commercially available clindamycin phosphate vaginal cream should be stored in a tight container at 20-25 °C; freezing should be avoided. The vaginal suppositories and clindamycin phosphate vaginal cream should be stored at a controlled room temperature of 25 °C, but may be exposed to temperatures ranging from 15-30 °C; exposure to temperatures exceeding 30 °C or high humidity should be avoided. When stored as recommended, the commercially available vaginal cream is stable for 18 months following the date of manufacture. /Clindamycin phosphate/|The commercially available gel containing clindamycin phosphate (clindamycin 1%) in fixed combination with benzoyl peroxide 5% should be refrigerated at 2-8 °C until dispensed.178 Once dispensed, the gel may be stored at a room temperature up to 25 °C for up to 60 days. The gel should not be frozen. /Clindamycin phosphate/|Commercially available clindamycin phosphate 1% topical gel, lotion, and solution should be stored in tight containers at 20-25 °C; freezing should be avoided. /Clindamycin phosphate/

    Vapor Pressure:

    5.28X10-17 mm Hg at 25 °C (est)

    Specific rotation:

    D +214° (chloroform)

    Henrys Law Constant:

    Henry's Law constant = 2.89X10-22 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    Characteristic taste; odorless or has faint mercaptan-like odor; freely soluble in water, dimethylformamide, methanol; soluble in alcohol; practically insoluble in acetone; pKa: 7.72 in pure water /Clindamycin hydrochloride/

    Experimental Properties:

    Mol wt: 479.47. White crystals from ethanol-ethyl acetate, mp 141-143 °C. Specific optical rotation = +144 deg at 25 °C/D (water). pKa 7.6. Soluble in water, pyridine, ethanol, DMF /Clindamycin hydrochloride monohydrate/|Mol wt: 504.97. Soluble in water /Clindamycin 2-dihydrogen phosphate/

    Hazard Identification

    Classification of the substance or mixture

    Eye irritation, Category 2

    Reproductive toxicity, Additional category for effects on or via lactation

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H319 Causes serious eye irritation

    H362 May cause harm to breast-fed children

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P203 Obtain, read and follow all safety instructions before use.

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P263 Avoid contact during pregnancy and while nursing.

    P270 Do not eat, drink or smoke when using this product.

    Response

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P318 IF exposed or concerned, get medical advice.

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store in tight container as defined in the USP-NF. This material should be handled and stored per label instructions to ensure product integrity.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Semaglutide,Tirzepatide,API,Vitamins,Food Additive

    Location:

    No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New City, Xi 'an, Shaanxi Province

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    5

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2019

    Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital Xi 'an, is committed to the peptide industry, pharmaceutical raw materials, food and feed additives, veterinary drugs and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products, "world peace and health" as its responsibility, the company adhering to the "meet all customer requirements for products" as the service concept, Guarantee "provide qualified products" as the service principle, so that you get "God-like" noble shopping enjoyment. Our company has more than 1000 kinds of polypeptides, raw materials inventory, at any time to meet the various needs of customers for products. Is your best partner.
  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Clindamycin

    1 KG Oct 1, 2024
    India

    CLINDAMYCIN

    10 KG Feb 10, 2025
    Post an enquiry for this product
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