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Methotrexate CAS 59-05-2

Name: Methotrexate CAS 59-05-2
Brand: airuike
SKU: pr2407081512
Price: 100 USD
Availability: InStock

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CAS No.:

59-05-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

SHANGHAI

Brand:

airuike

Packaging:

25kg/Cardboard Drum

Price valid (until):

2025-07-20

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Shandong Airuike Chemical Co., Ltd.

Company Type:

Trader

Location:

China

Qualification:

Main Products:

api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals

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Product Description
Seller Information
Inquiry History

Description

Shop Methotrexate CAS 59-05-2-Detailed Image 1

FAQ

Q : What is your terms of payment?
A : T/T 30% as deposit, and 70% before delivery or 100% L/C at sight.
Q : How to confirm the Product Quality before placing orders?
A : You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q : How about the delivery time?
A : Within 7 days after payment confirmation. (excluding Chinese holidays)

Q : What documents did you provide?
A :We usually provide commercial invoice, packing list, shipping list, waybill, health certificate and certificate of origin. If
there are any special requirements in your market, please let us know.Some technical paperwork is available, such as COA, HNMR, HPLC, LC-MS etc.

Q: How do you deal with quality complaints?
A : First of all, our quality control will ensure our quality. If we cause real quality problems, we will once again provide good
products or refund your losses.

Q : How do you make our business long-term and good relationship?
A : 1. We keep good quality and competitive price to ensure our customers benefit;
2. We respect every customer as our friend and we sincerely do business and make friends with them, no matter where they come from

Q : Do you have stock?
A: Yes, we have all our products in stock. Our annual output is 200 tons. No matter when you order, we will ship within 1 to 3 days.
Q : Why should I choose you?
A: Powerful technical support-come from our highly skilled & fully experienced staff, working in chemical industry for over
5years, in average.Strict quality control-comes form our sophisticated management system.Professional and warm sales team-since we
believe we can only win via our hard work in a competitive worldQuick response and excellent presale and after sale service-since
we believe our customers deserve all the best service.
Q : Can I get best price from you?
A: Of course. We don't chase excessive profits and alway

Basic Info

Product Name:

Methotrexate

Other Name:

METHOTREXATEFORINJECTION;sodium 4-[[4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]am ino]-5-hydroxy-5-oxo-pentanoate;METHOTREXATE(N-(4-(((2,4-DIAMINO-6-PTERIDINYL)METHYLAMINO)BENZOYL)-L-GLUTAMICACID);4-Amino-N10-methylfolic acid;Glutamic acid, N-[p-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, L-(+)- (8CI);L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]- (9CI);L-Methotrexate;Methotrexat-Ebewe

CAS No.:

59-05-2

Molecular Formula:

C20H22N8O5

InChIKeys:

FBOZXECLQNJBKD-ZDUSSCGKSA-N

Molecular Weight:

454.44

Exact Mass:

454.44

BRN:

70669

EC Number:

200-413-8

UNII:

YL5FZ2Y5U1

NSC Number:

740

UN Number:

3249

TSCA:

TSCA listed

DSSTox ID:

DTXSID4020822

NCI Thesaurus Code:

C642

Color/Form:

Light yellow to yellow

ATC Code:

L04AX03|L01BA01|L - Antineoplastic and immunomodulating agents

HScode:

29335995

Categories:

Antineoplastic Agents

Characteristics

PSA:

211

XLogP3:

-1.8

Appearance:

powder

Density:

1.4080 (rough estimate)

Melting Point:

195°C

Boiling Point:

561.26°C (rough estimate)

Flash Point:

11℃

Refractive Index:

1.6910 (estimate)

Water Solubility:

Insoluble. <0.1 g/100 mL at 19 ºC

Storage Conditions:

−20°C

Vapor Pressure:

2.1X10-19 mm Hg at 25 deg C /Estimated/

Toxicity:

LD50 oral in rat: 135mg/kg

Specific rotation:

Specific optical rotation: 20.4 + or - 0.6 deg at 21 °C/589 D (concentration by 0.1 N sodium hydroxide) maximum absorption: 243nm, A1= 388;307 nm, A1 = 475 (in 0.1 n hydrogen chloride). 258 nm, A1= 544; 303 nm, A1= 546; 372 nm, A1= 177 (in 0.1 N sodium hydroxide)

PKA:

pKa 3.04/4.99(H2O,t =25,I=0.0025) (Uncertain)

Henrys Law Constant:

Henry's Law constant = 1.5X10-31 atm-cu m/mol at 25 °C /Estimated/

Dissociation Constants:

4.7|pKa = 4.70 (carboxylic acid)|pKa = 3.5 carboxylic acid; pKa2 = 8.8, pKa3 = 9.2 (amines) /Estimated/

Collision Cross Section:

196.2 Å² [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]|194.8 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Experimental Properties:

Yellow crystals from dilute hydrogen chloride; decomp 185-204 °C (bath preheated to 160 °C). Max absorption (0.1 n hydrogen chloride): 244, 307 nm; max absorption (0.1 N sodium hydroxide): 257, 302, 370 nm; soluble in alkaline solns with decomposition /Methotrexate monohydrate/|Yellow powder; soluble in water. /Methotrexate sodium/|Hydroxyl radical reaction rate constant = 3.2X10-10 cu cm/molec-sec at 25 °C /Estimated/

Air and Water Reactions:

Methotrexate is sensitive to hydrolysis, oxidation and light. Insoluble in water.

Reactive Group:

Acids, Carboxylic

Reactivity Profile:

Methotrexate decomposes in very acidic or alkaline conditions. Methotrexate is incompatible with strong oxidizing agents and strong acids.

Critical Temperature & Pressure:

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

See More Methotrexate Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 3, Oral

Skin irritation, Category 2

Eye irritation, Category 2

Reproductive toxicity, Category 1B

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H301 Toxic if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H360 May damage fertility or the unborn child
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P203 Obtain, read and follow all safety instructions before use.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Methotrexate sodium tablets should be protected from light and stored in well-closed containers at 15-30 deg C. Methotrexate sodium injection and powder for injection should be protected from light and stored at 15-30 deg C. Methotrexate sodium

See More Methotrexate Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals

Location:
Huangdao District, Qingdao City, Shandong Province (formerly Room 606-2, Building 1, No. 10 Beijing Road, Jiaonan City)

Payment Terms:
TT against copy of documents,D/P,D/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15

Total Annual Revenue:
$5 million-$10 million

Total Employees:
51-100

Year of Establishment:
2023

Certifications:
Credit rating certificate,Hazardous Chemicals Business License

Company Profile
Foucsing on chemical industry,Shandong Airuike Chemical Co., LTD was established in the year 2013 and since then devoted all its efforts on how to bring best products and services to every customer,with intergrated sources and creative minds.
We are offering the market with Organic chemicals, Inorganic chemicals, Organic intermediates and water treatment products.
In construction industry,our furan resin product is high-light for metal casting as well as anticorrosion projecting for new chemical plant construction and repairing works.
Your consistent trust is our infinite power to move forward. Shandong Airuike Chemical Co., LTD never stop its step on technical researching,quality supervising,effective logistic arranging and on time services to fully satisfy customers requests. We also extended our product range by close cooperating with famous producers all around China,around the world.
By now we have established business relationship with more than 200 customers around the world.
Like our company motto says,”Innovation as power,quality as life,be honest people practical development”,Shandong Airuike Chemical Co., LTD team always put sincerity and honesty in the first place and in return customers trust us and develop win-win cooperation betwwen each other.
You’re always welcomed to contact us and share your needs,let us give you an unique satisfying for our business cooperation together.

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	METHOTREXATE IP/BP/USP	1.00 KG	Jul 4, 2025
India	Methotrexate	1.00 KG	Dec 11, 2023

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