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TPX-0005 CAS 1802220-02-5 supply high quality fast delivery best service

Name: TPX-0005 CAS 1802220-02-5 supply high quality fast delivery best service
Brand: Million
SKU: pr2407121053
Price: 2.53 USD
Availability: InStock

Unit Price: Get Latest Price 

CAS No.:

1802220-02-5

Grade:

Pharmaceutical Grade

Content:

99.58%

Brand:

Million

Packaging:

25kg/Cardboard Drum

Sample Available:

Yes

Price valid (until):

2024-10-19

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Jinan Million Pharmaceutical Co., Ltd

Company Type:

Manufactory

Location:

China

Payment Terms:

L/C,100% TT in advance

Average Lead Time:

3 days

Qualification:

Main Products:

Avanafil,Tirzepatide,Semaglutide,Pregabalin,Nootropics,MT2

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Product Description
Seller Information

Description

Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 1

-Product Descrition-

Million focuses on the new drug Repotrectinib (TPX-0005). TPX 0005 is a rationally designed, low-molecular-weight, macrocyclic TKI that is selective and highly potent against ROS1, TRKA–C, and ALK. Most importantly, repotrectinib exhibits activity against a variety of solvent-front substitutions in vitro and in vivo. Repotrectinib achieved confirmed responses in patients with ROS1 or NTRK3 fusion–positive cancers who had relapsed on earlier-generation TKIs due to ROS1 or TRKC solvent-front substitution-mediated resistance.

Bristol Myers Squibb (NYSE:BMY) and Turning Point Therapeutics, Inc. (NASDAQ:TPTX) have a definitive merger agreement under which Bristol Myers Squibb will acquire Turning Point Therapeutics for $76.00 per share which is quite hight. BMS has seen the big potential of Repotrectinib, so as Jinan Million Pharm. We already r & D and make it commercial production. Once FDA approved it, Jinan Million will have stock of tpx 0005 api powder in stock and ready shipment. We will be the first manufacturer and factory of Repotrectinib

Name	TPX-0005
MF	C18H18FN5O2
MW	355.37
CAS	1802220-02-5

Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 2

Why Choose Us ？

1 、 Manufacturer supply, best price and service.

2、 Safe fast delivery.

3、 F ree sample.

4、 Large stock.

5、 Easy payment: bank transfer, moneygram, paypal....

6、 Good reputation, great feedback.

7、 Customers worldwide: Metrochem Api Pvt Ltd;Bdr Lifesciences Pvt.Ltd;Srini Chem;Eva Pharma;Pharmaffiliates Analytics&Synthetics(p)Ltd;....From India,Egypt,Canada ....

-Packing&Shipping-

Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 3

Ship methods	Special line	Express	By air	By sea
Ship methods	Special line	DHL/TNT/FeDex/UPS	By air	By sea
Delivery	7-15 days	3-10 days	3-5 days	10-30 days
Service	Door to door	Door to door	To airport	To seaport
Customs clearance	No	Possible	Yes	Yes

-Company Profile-

Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 4

Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 5

About us:

Founded in 2012, Jinan Million Pharmaceutical Co., Ltd (Jinan Milin Pharmaceutical Co., Ltd) is a modern pharmaceutical enterprise guided by innovation. Million pharm has excellent research and development capabilities and complete industrial bases with international quality management system. It is dedicated to the research, development, production and customization of pharmaceuticals and advanced pharmaceutical intermediates.

Jinan Million Pharmaceutical Co., Ltd has been focusing on the research of Cerebro-cardiovascular drugs, Central nervous system drugs, Anti-cancer drugs, Antibacterial drugs and others for 12 years; the products are: Apixab a n, Lurasidon e , Bexagliflozin, Vortioxetine, L OXO -292/Selpercatinib, Baricitinib and intermediates. Million has worked with reputable customers, like METROCHEM API PVT LTD; BDR LIFESCIENCES PVT.LTD; SRINI CHEM; EVA PHARMA; PHARMAFFILIATES ANALYTICS & SYNTHETICS (P) LTD; ....from India, Egypt, Canada...

Jinan Million Pharmaceutical Co., Ltd has a 1,500㎡ R&D center in the Zhongguancun E Valley (Qihe) Incubator, equipped with complete test equipment, such as high-performance liquid chromatography, nuclear magnetic resonance spectrometer, liquid chromatography mass spectrometer, automatic polarimeter, etc., which can meet the needs of various laboratory scale tests in different conditions. The pilot workshop is equipped with 50L and 100L glass reactors, high and low temperature equipment, etc., which can support organic chemical reactions at -100°C or 200°C. In addition, Million has a production site in Linyi city with many independent production lines, such as: production line of Apixabn intermediate 20 tons/year, production line of Lurasidon intermediate 10 tons/year, which can meet the commercial production of various products.

The technical team is composed of high-level talents in major of pharmacy, bio-pharmaceutical or chemical synthesis, of which 10% has doctor’s degree and 15% has master’s degree. The team members are young and energetic with innovative spirit and willing to overcome obstacles.

Jinan Million Pharmaceutical Co., Ltd adheres to the business philosophy of "dedication and innovation", insists on pioneering and innovating, constantly improves the quality system, and vigorously trains technical and management talents to build an elite team and serves customers better. Looking forward to cooperate with you for joint development and common progress.

-Certification- Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 6

ECHEMI Editorial Reference

Repotrectinib is an orally available inhibitor of multiple kinases, including the receptor tyrosine kinase anaplastic lymphoma kinase (ALK), c-ros oncogene 1 (ROS1), the neurotrophic tyrosine receptor kinase (NTRK) types 1, 2 and 3, the proto-oncogene SRC, and focal adhesion kinase (FAK), with potential antineoplastic activity. Upon oral administration, repotrectinib binds to and inhibits wild-type, point mutants and fusion proteins of ALK, ROS1, NTRK1-3, SRC, FAK and, to a lesser extent, other kinases. Inhibition of these kinases leads to the disruption of downstream signaling pathways and the inhibition of cell growth of tumors in which these kinases are overexpressed, rearranged or mutated.

Basic Info

Product Name:

Repotrectinib

Other Name:

Repotrectinib;TPX-0005;1802220-02-5;08O3FQ4UNP;TPX0005;UNII-08O3FQ4UNP;TRX-0005;Repotrectinib (USAN);Repotrectinib [USAN];(3R,11S)-6-fluoro-3,11-dimethyl-10-oxa-2,13,17,18,21-pentazatetracyclo[13.5.2.04,9.018,22]docosa-1(21),4(9),5,7,15(22),16,19-heptaen-14-one

CAS No.:

1802220-02-5

Molecular Formula:

C18H18FN5O2

InChIKeys:

FIKPXCOQUIZNHB-WDEREUQCSA-N

Molecular Weight:

355.4

Exact Mass:

355.14445300

UNII:

08O3FQ4UNP

NCI Thesaurus Code:

C133821

Categories:

Antineoplastic Agents

Seller Information

Business Type:
Manufactory

Main Products:
Avanafil,Tirzepatide,Semaglutide,Pregabalin,Nootropics,MT2

Location:
Room 1-2208, Lianhecaifu Square, No2177, Tianchen Road, Gaoxin District, Jinan City, Shandong Province, China

Payment Terms:
L/C,100% TT in advance

Average lead Time:
3 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2012

Company Certificates
- business license
Founded in 2012, Jinan Million Pharmaceutical Co., Ltd (Jinan Milin Pharmaceutical Co., Ltd) is a modern pharmaceutical enterprise guided by innovation. Million pharm has excellent research and development capabilities and complete industrial bases with international quality management system. It is dedicated to the research, development, production and customization of pharmaceuticals and advanced pharmaceutical intermediates.

Jinan Million Pharmaceutical Co., Ltd has been focusing on the research of Cerebro-cardiovascular drugs, Central nervous system drugs, Anti-cancer drugs, Antibacterial drugs and others for 12 years; the products are: Apixaban, Lurasidone, Bexagliflozin, Votioxitine, Loxo-292/Selpercatinib, Baricitinib and intermediates. Million has worked with reputable customers, like METROCHEM API PVT LTD; BDR LIFESCIENCES PVT.LTD; INCETPAT PHARM; SRINI CHEM; EVA PHARMA; PHARMAFFILIATES ANALYTICS & SYNTHETICS (P) LTD; ....from India, Egypt, Canada...

Jinan Million Pharmaceutical Co., Ltd has a 1,500㎡ R&D center in the Zhongguancun E Valley (Qihe) Incubator, equipped with complete test equipment, such as high-performance liquid chromatography, nuclear magnetic resonance spectrometer, liquid chromatography mass spectrometer, automatic polarimeter, etc., which can meet the needs of various laboratory scale tests in different conditions. The pilot workshop is equipped with 50L and 100L glass reactors, high and low temperature equipment, etc., which can support organic chemical reactions at -100°C or 200°C. In addition, Million has a production site in Linyi city with many independent production lines, such as: production line of Apixabn intermediate 20 tons/year, production line of Lurasidon intermediate 10 tons/year, which can meet the commercial production of various products.

The technical team is composed of high-level talents in major of pharmacy, bio-pharmaceutical or chemical synthesis, of which 10% has doctor’s degree and 15% has master’s degree. The team members are young and energetic with innovative spirit and willing to overcome obstacles.

Jinan Million Pharmaceutical Co., Ltd adheres to the business philosophy of "dedication and innovation", insists on pioneering and innovating, constantly improves the quality system, and vigorously trains technical and management talents to build an elite team and serves customers better. Looking forward to cooperate with you for joint development and common progress.
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Product Name	Grade / Content	Supplier Name	Details
TPX-0005	Industrial Grade/99	Shaanxi Dideu Medichem Co. Ltd	Inquiry
TPX-0005	/99.00	HANGZHOU LEAP CHEM CO., LTD.	Inquiry
Jinlan 98+ EP/BP/USP Repotrectinib	medical grade/98	Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd	Inquiry
Repotrectinib	/	Chiyan	Inquiry
Repotrectinib/TPX-0005 CAS 1802220-02-5 high quality can be supplied from stock in fast delivery	Pharmaceutical Grade/99	Jinan Million Pharmaceutical Co., Lt	Inquiry

TPX-0005 CAS 1802220-02-5 supply high quality fast delivery best service

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