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Jinlan 98+ EP/BP/USP Repotrectinib

Name: Jinlan 98+ EP/BP/USP Repotrectinib
Brand: Jinlan
SKU: pr26012240671
Price: 201 USD
Availability: InStock

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CAS No.:

1802220-02-5

Grade:

medical grade

Content:

98%

Port:

Shanghai/Ningbo/Qingdao

Brand:

Jinlan

Packaging:

25kg/Cardboard Drum

Sample Available:

Yes

Price valid (until):

2026-03-01

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

Company Type:

Trader

Location:

China

Payment Terms:

100% TT in advance

Average Lead Time:

275 days

Qualification:

Main Products:

Peptides,API,Intermediate

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Product Details
Seller Information

Description

Product Detail

Repotrectinib (1802220-02-5)

Basic Product Description

CAS Number: 1802220-02-5

Chemical Name: (S)-N-(5-((3,5-Difluorophenyl)amino)-1H-pyrazol-3-yl)-3-(hydroxymethyl)-1-methylpiperidine-4-carboxamide

Molecular Formula: C₂₃H₂₂F₂N₆O₂

Molecular Weight: 436.46 g/mol

Synonyms: Augtyro®, TPX-0005

Related Categories: Next-Generation ALK/ROS1/NTRK Inhibitor, Oral Selective Tyrosine Kinase Inhibitor (TKI), Multi-Targeted Fusion Kinase Inhibitor, ALK/ROS1/NTRK-Positive NSCLC & Solid Tumor Therapeutic

Key Highlight: A potent, next-generation oral TKI with pan-inhibitory activity against ALK, ROS1 and NTRK fusion mutations, including a broad spectrum of acquired resistance mutations; features exceptional central nervous system (CNS) penetration, effective for brain metastases; indicated for ALK/ROS1-positive metastatic NSCLC and NTRK fusion-positive solid tumors, exerts anti-tumor effects by blocking aberrant fusion kinase signaling to inhibit tumor cell proliferation and survival.

ECHEMI Editorial Reference

Repotrectinib is an orally available inhibitor of multiple kinases, including the receptor tyrosine kinase anaplastic lymphoma kinase (ALK), c-ros oncogene 1 (ROS1), the neurotrophic tyrosine receptor kinase (NTRK) types 1, 2 and 3, the proto-oncogene SRC, and focal adhesion kinase (FAK), with potential antineoplastic activity. Upon oral administration, repotrectinib binds to and inhibits wild-type, point mutants and fusion proteins of ALK, ROS1, NTRK1-3, SRC, FAK and, to a lesser extent, other kinases. Inhibition of these kinases leads to the disruption of downstream signaling pathways and the inhibition of cell growth of tumors in which these kinases are overexpressed, rearranged or mutated.

Basic Info

Product Name:
Repotrectinib

Other Name:
Repotrectinib;TPX-0005;1802220-02-5;08O3FQ4UNP;TPX0005;UNII-08O3FQ4UNP;TRX-0005;Repotrectinib (USAN);Repotrectinib [USAN];(3R,11S)-6-fluoro-3,11-dimethyl-10-oxa-2,13,17,18,21-pentazatetracyclo[13.5.2.04,9.018,22]docosa-1(21),4(9),5,7,15(22),16,19-heptaen-14-one

CAS No.:
1802220-02-5

Molecular Formula:
C18H18FN5O2

InChIKeys:
FIKPXCOQUIZNHB-WDEREUQCSA-N

Molecular Weight:
355.4

Exact Mass:
355.14445300

UNII:
08O3FQ4UNP

NCI Thesaurus Code:
C133821

Categories:
Other Chemical Drugs
Seller Information

Business Type:
Trader

Main Products:
Peptides,API,Intermediate

Location:
Room 606, Building 1, Fu Yi Commercial Center, Shangcheng District, Hangzhou City, Zhejiang Province - 1

Payment Terms:
100% TT in advance

Average lead Time:
275 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
51-100

Year of Establishment:
2020

Hangzhou Jinlan Pharm-Drugs Technology Co., Ltd (with its export company Hangzhou Royall Import & Export Co.,Ltd.) is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int' l Airport and Shanghai Pudong Int' l Airport, the transportation and production environment are excellent. JINLAN PHARMA mainly business includes: 1) API, Pharmaceutical Intermediates, CMO, CRO, CDMO and so on. 2) Pharmaceutical Equipment such as: Distilled Water Machinery, Mixer, Sterilizer and so on.

JINLAN PHARM focus on:

■ Contrast Agent

■ Anti-COVID APIs

■ Respiratory System APIs

■ Anti-tumor & Anti-Cancer APIs

■ Anti-Diabetes APIs

■ Anti-HCV & Anti-HBV APIs

■ Anti-HIV APIs

■ Peptides

■ Pharmaceutical Intermediates

■ CMO, CRO, CDMO
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Jinlan 98+ EP/BP/USP Repotrectinib

Product Details

Seller Information

Repotrectinib (1802220-02-5)

Basic Product Description

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