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Home > Active Pharmaceutical Ingredients > Other Chemical Drugs > Sulfanilamide for Sale > Pharmaceutical Antibiotic Intermediates CAS63-74-1 Sulfanilamide / Sulfonylamide
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Pharmaceutical Antibiotic Intermediates CAS63-74-1 Sulfanilamide / Sulfonylamide

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Unit Price: Get Latest Price
CAS No.:

63-74-1

Grade:

Industrial Grade

Content:

99%

Port:

china any port

Brand:

TNJONE

Packaging:

1kg ,25kg or according to customer's detail requirement.

Price valid (until):

2025-12-31

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Semaglutide,Tirzepatide,API,Vitamins,Food Additive

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Pharmaceutical Antibiotic Intermediates CAS63-74-1 Sulfanilamide / Sulfonylamide

    What is Sulfanilamide / Sulfonylamide?


    Sulfanilamide, also known as Sulphanilamide, 4-Aminobenzenesulfonamide or p-Aminobenzenesulfonamide, is a chemical compound that serves as an intermediate in the synthesis of various pharmaceutical compounds. As an intermediate, sulfanilamide plays a crucial role in the production of drugs belonging to the sulfonamide class.

    Sulfanilamide itself has antimicrobial properties and was one of the first synthetic antibiotics to be used in the treatment of bacterial infections. However, its primary use today is as a starting material or building block for the synthesis of other drugs.

    The chemical structure of sulfanilamide contains a sulfonamide group (-SO2NH2) attached to a benzene ring. This functional group is important for its antimicrobial activity and serves as a key component in the synthesis of sulfonamide antibiotics.

    Through chemical modifications and reactions, sulfanilamide can be transformed into a variety of derivatives with enhanced pharmacological properties. These derivatives can exhibit antimicrobial, antifungal, diuretic, anticonvulsant, or analgesic activities, depending on the specific modifications made.

    As an intermediate, sulfanilamide is used in multi-step synthesis processes, where it undergoes various chemical transformations to create more complex drug molecules. It acts as a starting point for introducing additional functional groups or modifying the chemical structure to improve the desired therapeutic properties of the final drug product.

    Overall, sulfanilamide as an intermediate plays a vital role in the pharmaceutical industry, enabling the synthesis of a diverse range of drugs that are used to treat bacterial infections, fungal infections, epilepsy, pain, and other medical conditions. 

    Items Specifications
    Product name Sulfanilamide / Sulfonylamide
    CAS No. 63-74-1
    MF C6H8N2O2S
    MW 172.2
    EINECS.No 200-563-4
    Melting Point 164-166 °C(lit.)
    Boiling Point 400.5±47.0 °C(Predicted)
    Density 1.08
    Appearance White powder
    Shelf Life 2 Years When Properly Stored
    Storage Keep in a cool, dry, dark location in a tightly sealed container or cylinder.


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    Certification 

    Items

    Standards

    Results

    Physical Analysis

       

    Description

    White Powder Complies

    Assay

    99% 99.6%

    Mesh Size

    100 % pass 80 mesh Complies

    Ash

    ≤ 5.0% 2.85%

    Loss on Drying

    ≤ 5.0% 2.65%

    Chemical Analysis

       

    Heavy Metal

    ≤ 10.0 mg/kg

    Complies

    Pb

    ≤ 2.0 mg/kg

    Complies

    As

    ≤ 1.0 mg/kg Complies

    Hg

    ≤ 0.1mg/kg Complies

    Microbiological Analysis

       

    Residue of Pesticide

    Negative Negative

    Total Plate Count

    ≤ 1000cfu/g Complies

    Yeast&Mold

    ≤ 100cfu/g Complies

    E.coil

    Negative

    Negative

    Salmonella

    Negative

    Negative


    Function

    1.Used in the pharmaceutical industry, is the main raw material for the synthesis of sulfa drugs
    2.It is an important intermediate of sulfa drugs.
    3.It has a wide antimicrobial spectrum, hemolytic streptococcus, neisseria meningitidis, staphylococcus aureus and other gram-positive and negative bacteria are antimicrobial effect.This product is a local drug, but since the part  of the absorption of the wound.Used for hemolytic streptococcus, staphylococcus of trauma, infection, etc.Quickly can  also be used to stop the bleeding.

    Application

    1. Sulfonamide Antibiotics
    Sulfanilamide and its derivatives have been used in the production of sulfonamide antibiotics, such as sulfadiazine, sulfamethoxazole, and sulfisoxazole. These antibiotics are used to treat various bacterial infections.

    2. Antifungal Agents
    Sulfanilamide derivatives have been employed in the synthesis of antifungal agents, such as clotrimazole and miconazole. These medications are used to treat fungal infections.

    3. Diuretics
    Sulfanilamide derivatives have been utilized in the synthesis of certain diuretic drugs, such as acetazolamide. Diuretics increase urine production and are used to treat conditions like edema and high blood pressure.

    4. Anticonvulsants
    Sulfanilamide-based compounds have been used in the development of anticonvulsant medications, such as ethosuximide. These drugs are prescribed to manage and prevent seizures in individuals with epilepsy.

    5. Analgesics
    Sulfanilamide derivatives have been employed in the synthesis of analgesic drugs, such as acetaminophen (paracetamol). These medications are commonly used to relieve pain and reduce fever.

    Company Information 


    Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital of Xi 'an, is committed to pharmaceutical raw materials, kill varieties, food and feed additives, chemical reagents, plant extracts and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products. Our company after careful planning, hard study, gradually formed a complete service system, based on the domestic and foreign raw materials market special development. Make the raw materials industry bigger and stronger, and serve the vast number of new and old customers. With "world peace and health" as its responsibility, the company adheres to the service concept of "meeting all requirements of customers for products", and guarantees the service principle of "providing qualified products", so that you can get the "God-like" noble shopping enjoyment. Our company has more than 500 kinds of raw materials inventory at any time to meet the various needs of customers for products. The company's products all comply with the relevant national regulations, from the smallest packaging to tons of goods are available. Is your choice of raw materials the best partner.


    Shaanxi TNJONE Pharmaceutical Technology Co., Ltd. is willing to rely on the rapid development of e-commerce and national policy support of the good environment background, nesting, welcome people from all walks of life to visit our company, exchange, and seek common development, looking forward to sharing with you, win-win, to realize the dream.


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    FAQ

    1.How to get in touch with us?

    You can chat with us by Trademanager,WhatsApp or simply giving us an email, a phone call. All our contacts information can be found from our website.

     

    2.Are you a manufacturer or trade company?

    We are a professional manufacturer.

     

    3.Can I get a sample?

    Yes, free sample can be provided, but shipping cost is covered by your side.

     

    4.What's your MOQ?

    It is based on the different product. Some are 1g while some are 1 kg. Please be free to consult our salesman.

     

    5.When can I get the quotation?
    We usually quote within 1 hours after we get your inquiry. If it's a urgent order you can call us or mention it in your email subject, and we can take it as priority.

     

    6.Is there any discount?
    Yes, some products are applied for discount, but it depends on the quantity.

     

    7.Can you do OEM for me?
    Yes,we accept OEM orders, just contact us and give us your requirement. We will offer you a reasonable price and make samples ASAP.

    Basic Info
    Product Name:

    Sulfanilamide

    Other Name:

    Benzenesulfonamide,4-amino-;Sulfanilamide;4-Aminobenzenesulfonamide;F 1162;Albexan;Albosal;Ambeside;p-Aminobenzenesulfonamide;4-Aminophenylsulfonamide;p-Anilinesulfonamide;Antistrept;Astreptine;Astrocid;Bacteramid;Bactesid;Collomide;Colsulanyde;Copticide;Deseptyl;Ergaseptine;Erysipan;Estreptocida;Fourneau 1162;Gerison;Gombardol;Lusil;Lysococcine;Neococcyl;Orgaseptine;PABS;Prontalbin;Prontosil I;Prontosil Album;Prontosil white;Prontylin;Pronzin Album;Proseptal;Proseptine;Proseptol;Pysococcine;Rubiazol A;Sanamid;Septamide Album;Septanilam;Septinal;Septolix;Septoplex;Septoplix;Stopton Album;Stramid;Strepamide;Strepsan;Streptagol;Streptamid;Streptasol;Streptocid album;Streptoclase;Streptocom;Strepton;Streptosil;Streptozol;Streptozone;p-Sulfamidoaniline;Sulfamidyl;Sulfamine;Sulfana;Sulfanalone;Sulfanil;Sulfocidine;Sulphanilamide;Therapol;White streptocide;Sulfonamide P;Dipron;p-Aminophenylsulfonamide;A-349;Sulphonamide;Sulfonamide;Sulfonylamide;4-Sulfamoylaniline;Streptocid;p-Sulfamoylaniline;Streptocide (white);Exoseptoplix;Sulfanidyl;Tolder;Infepan;Streptopan;Streptocide;4-(Aminosulfonyl)aniline;Ro 1-3354;1162F;Sulfanilamide Vaginal Cream;(4-(Aminosulfonyl)phenyl)amine;NSC 7618;4-Aminobenzene-1-sulfonamide;Azol;Sulfonamid;4-Aminobenzenesulfonic acid amide;102489-34-9;1337-36-6;1337-39-9;12765-80-9;24706-25-0

    CAS No.:

    63-74-1

    Molecular Formula:

    C6H8N2O2S

    InChIKeys:

    InChIKey=FDDDEECHVMSUSB-UHFFFAOYSA-N

    Molecular Weight:

    172.2

    Exact Mass:

    172.20

    BRN:

    511852

    EC Number:

    200-563-4

    UNII:

    21240MF57M

    NSC Number:

    757404|7618

    UN Number:

    1759

    DSSTox ID:

    DTXSID4023622

    NCI Thesaurus Code:

    C47738

    Color/Form:

    LEAFLETS FROM AQ ALCOHOL|CRYSTALS

    ATC Code:

    D - Dermatologicals|J - Antiinfectives for systemic use

    HScode:

    2935009090

    Categories:

    Other Chemical Drugs

    Characteristics
    PSA:

    94.6

    XLogP3:

    -0.6

    Appearance:

    white to faintly beige Liquid

    Density:

    1.08 g/cm3 @ Temp: 25 °C

    Melting Point:

    165.5 °C

    Boiling Point:

    400.5°C at 760 mmHg

    Flash Point:

    196.0±29.3 °C

    Refractive Index:

    1.628

    Water Solubility:

    H2O: 7.5 g/L at 25 ºC

    Storage Conditions:

    0-6°C

    Vapor Pressure:

    0.00001 hPa (70 °C)

    Toxicity:

    Oral-Rat LD50: 3900 mg/kg; Oral-Mouse LD50: 3000 mg/kg

    Flammability characteristics:

    Combustible in case of open flame, high temperature and strong oxidants; burning emits nitrogen oxides and sulfur oxides to stimulate smoke

    PH:

    NEUTRAL TO LITMUS; PH OF 0.5% AQ SOLN: 5.8-6.1

    PKA:

    10.6(at 20 °C)

    Dissociation Constants:

    10.6 (at 20 °C)|pKa = 10.43, pKb = 11.63|pKa = 10.58

    Collision Cross Section:

    156.07 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|152.77 Ų [M+Na]+ [CCS Type: DT, Method: stepped-field]|141.7 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|141.2 Ų [M-H]-

    Experimental Properties:

    WHITE CRYSTALS, GRANULES OR POWDER /NF X1/

    Air and Water Reactions:

    May be unstable if exposed for long periods air and light (NTP, 1992). Slightly water soluble.

    Reactive Group:

    Sulfonates, Phosphonates, and Thiophosphonates, Organic

    Reactivity Profile:

    SULFANILAMIDE is an amino acid. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May react with azo and diazo compounds to generate toxic gases.

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Eye irritation, Category 2

    Specific target organ toxicity – single exposure, Category 3

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H315 Causes skin irritation

    H319 Causes serious eye irritation

    H335 May cause respiratory irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Semaglutide,Tirzepatide,API,Vitamins,Food Additive

    Location:

    No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New City, Xi 'an, Shaanxi Province

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    5

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2019

    Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital Xi 'an, is committed to the peptide industry, pharmaceutical raw materials, food and feed additives, veterinary drugs and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products, "world peace and health" as its responsibility, the company adhering to the "meet all customer requirements for products" as the service concept, Guarantee "provide qualified products" as the service principle, so that you get "God-like" noble shopping enjoyment. Our company has more than 1000 kinds of polypeptides, raw materials inventory, at any time to meet the various needs of customers for products. Is your best partner.
  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Sulphanilamide

    1 KG Mar 2, 2024
    Post an enquiry for this product
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