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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Retatrutide for Sale > New arrival Triple Hormone Receptor Agonist GLP-1 Purity 99% 15mg Retatrutide
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New arrival Triple Hormone Receptor Agonist GLP-1 Purity 99% 15mg Retatrutide

TDS 7433 Inquiries

Unit Price: Get Latest Price
CAS No.:

2381089-83-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shenzhen

Brand:

subi

Packaging:

1g/vail; 2g/vail; 5g/vail; 10g/vail; 50g/vail

Sample Available:

Yes

Price valid (until):

2024-08-29

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents
Average Lead Time:
3 days
Qualification:
Main Products:

peptone

  • Product Details

  • Seller Information

  • Inquiry History

  • Description


      Product Description  



    Retatrutide (LY3437943) is a triple agonist of the glucagon receptor, glucose-dependent insulinotropic polypeptide receptor, and glucagon-like peptide-1 receptor (GLP-1R), and inhibits GCGR, GIPR, and GLP-1R.Retatrutide can be used to study obesity.

    In vivo, Retatrutide (LY3437943) engages with GCGR and, when administered through subcutaneous injection at a single dose of 0.47 mg/kg, improves glucose tolerance in an ipGTT (intraperitoneal glucose tolerance test) through activation of GIP or GLP-1 receptors.
    With subcutaneous injections at 10 mL/kg every 3 days in a cycle sustained for 21 days, Retatrutide leads to significant weight reduction and increased energy expenditure through activation of glucagon receptor.

    The product advantage information:

    a. High quality with competitive price

    b. GMP workshop

    c. Rich experience on registration



    Items Specifications
    Appearance White powder
    CAS 2381089-83-2
    Storage    Keep in a cool, dry, dark location


    Packing:

    10mg/vial 10vials/box

    15mg/vial 10vials/box

    20mg/vial 10vials/box 

    30mg/vial 10vials/box 


    Basic Information

    Retatrutide, LY3437943

    CAS#: 2381089-83-2

    Molecular Formula: C221H342N46O68

    Molecular Weight: 4731.33

    Sequence: H-Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-α-Me-Leu-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

    Appearance: White Powder

    Purity (HPLC): ≥99.0%

    Single Impurity (HPLC): ≤1.0%

    Sodium Content (HPLC): 5.0%-12.0%

    Moisture Content (Karl Fischer): ≤10.0%

    Peptide Content: ≥80.0%

    Storage: Store at 2-8 degrees Celsius in a dry and cool place.

    Packaging: 1g-1kg, plastic bottle

    Intended Use: For scientific research purposes



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    Inquiry guide

    1. Please send the quantity(Weight) to us, we will arrange our sales to provide the one-for-one service for you.

    2.Then we will provide the professional quotation list for you, it will be including all the factors in whole business process(Quality, shipping, payment, files etc.).

    3.If you have many products need inquiry, please send the list for us, the product clear information includes CAS + Name + quantity(Weight), we will provide the complete solution for you. We also provide the customization product.


    FAQ:

    Q1: Are you trading company or manufacturer?

    A1: We are chemical manufacturerin China. So we can provide wholesale price.
    Q2: Why is the quoted price different from the listed price?
    A2: As we all know, the price of chemicals is not fixed, butfluctuates with the market.
    Q3: Has the quality of your products passed the test of a third-party authoritative testing agency?
    A3: Yes, all products are strictly tested by our quality control before shipment, and the quality assurance is confirmed and
    approved by third-party laboratories in China, the United States, Canada, Germany, the United Kingdom, Italy, France and other
    countries. If you choose us, we will guarantee to provide you with the highest quality products and services.
    Q4: If the inspection result can not meet the agreement between the two sides, can you bear all the losses caused by this?
    A4: Yes, we can. We guarantee that the samples provided will meet the needs of our clients and we will bear the risk of default.
    Q5: How can I get samples, how much is the MOQ, and how can I confirm the product quality?
    A5: We can offer you free samples of our existing products, the delivery time is about 1-3 days, you only need to pay the sample
    shipping cost. Our MOQ starts from 1g-1000g. Confirm the product quality You can send us your product specifications and parameter
    requirements, we will manufacture the product according to your parameter requirements or provide according to the sample quality
    parameters.
    Q6: What are your payment terms?
    A6: We can accept various payment methods,  T/T, T/T, BTC (Bitcoin), etc.
    Q7: Are there any discounts?
    A7: Yes, for bulk purchase orders, we always support with better price.
    Q8: How about the delivery time?
    A8: The delivery time is about 7-20 days after confirming the payment. Delivery times vary from country to country. (excluding
    Chinese holidays)

    For payment: We can accept Bitcoin,Paypal, bank TT to company, bank TT to private account

    How to proceed an order?
    Step 1: When you intended to buy something, pls send me an inquiry by email.
    Step2: I will reply you with a quotation as soon as I receive you inquiry.
    Step3: We will negotiate products, price, package, payment methods and so on.
    Step4: You arrange the payment.
    Step5: I will arrange the shipment after receiving you money.
    Step6: The tracking number of the parcel will be sent to you.
    Step7: Trace the tracking number on website until you receive it.

    ECHEMI Editorial Reference
    Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191 and 0.794 nM, respectively. It is an important tool for obesity research.Retatrutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R.Retatrutide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes (T2D), stimulating insulin and suppressing glucagon secretion in a glucose-dependent manner.Retatrutide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes.
    Retatrutide (LY-3437943) was discovered by the American pharmaceutical company Eli Lilly and Company. It is a triple glucagon hormone receptor agonist (GLP-1, GIP, and GCGR receptors) for obesity. The 2024 Lasker~DeBakey Clinical Medical Research Award has been given to Joel Habener and Svetlana Mojsov for their discovery of a new hormone GLP-1(7-37) and to Lotte Knudsen for her role in developing sustained acting versions of this hormone as a treatment for obesity.

    Certificates

    Basic Info
    Product Name:

    Retatrutide

    Other Name:

    Retatrutide;GIPR/GLP-1R;LY3437943Retatrutide;Retalutide;Retatrutide (sodium salt);Retatrutide RT5;retatrutide 5mg;Retatratide

    CAS No.:

    2381089-83-2

    InChIKeys:

    MLOLQJNKXBNWFW-SAGGEDDASA-N

    Molecular Weight:

    0

    EC Number:

    200-001-8

    Color/Form:

    White lyophilized

    Characteristics
    Water Solubility:

    Soluble in water (5mg/ml).

    Storage Conditions:

    -20°C

    Critical Temperature & Pressure:

    -20°C

    Research
    Class:

    Triple agonist — GCGR, GIPR, GLP-1R

    Status:

    Investigational (Phase 3)

    Mechanism:

    Simultaneously activates glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Engineered from the native GIP backbone with amino acid substitutions to confer GCGR and GLP-1R activity.

    EC50 (Human GCGR):

    5.79 nM

    EC50 (Mouse GIPR):

    0.191 nM

    EC50 (Mouse GLP1R):

    0.794 nM

    EC50 (Mouse GCGR):

    2.32 nM

    EC50 (Human GLP1R):

    0.775 nM

    EC50 (Human GIPR):

    0.0643 nM

    Source:

    Jastreboff AM, et al. N Engl J Med. 2023;389(6):514-526.DOI

    Clinical Development:

    NCT04881760; NCT05882045; NCT06354660

    References
    ChEMBL:

    CHEMBL5095485

    DrugBank:

    DB18993

    KEGG DRUG:

    D12430

    PubChem:

    PubChem

    Disclaimer:

    Retatrutide is an investigational compound not yet approved by FDA or EMA. This listing is for industrial and laboratory research use only. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    peptone

    Location:

    Room A109, No. 29 Dongting Road, Hexi District, Tianjin

    Payment Terms:

    TT against copy of documents

    Average lead Time:

    3 days

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    Less than 5

    Year of Establishment:

    2024

  • Inquiry History
    7433 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Retatrutide 2381089-83-2

    3 MT Mar 28, 2026
    United Kingdom

    Retatrutide - 2381089-83-2

    1 G Feb 10, 2026
    United States

    Retatrutide CAS 2381089-83-2 10mg vial

    20 MT Mar 7, 2026
    United States

    Factory Retatrutide API 99% Purity CAS 2381089-83-2

    5 KG Nov 10, 2025
    United Kingdom

    Peptide powder Retatrutide 99% pure for Body building cas 2381089-83-2 Weight Loss Peptide with COA

    1 MT Mar 22, 2026
    United States

    2381089-83-2

    100 G Jul 14, 2026
    United States

    2381089-83-2

    100 G Feb 24, 2026
    United States

    2381089-83-2

    100 MT Dec 9, 2023
    United States

    Retatrutide 2381089-83-2

    200 MG May 16, 2026
    United Kingdom

    2381089-83-2 retatrutide

    300 MG Feb 13, 2026
    United States

    Retatrutide 2381089-83-2 wholesale

    500 MT Nov 3, 2023
    Poland

    CAS 2381089-83-2 (Custom Peptide)

    40 MT Apr 10, 2026
    Austria

    Peptide Retatruide CAS 2381089-83-2

    100 MT Apr 4, 2026
    United States

    Retatrutide CAS 2381089-83-2 99%

    10 PCS Feb 21, 2026
    Austria

    Retatrutide CAS 2381089-83-2 10mg vial

    20 PCS Feb 10, 2026
    United States

    GLP-1 / GIP Retatrutide cas 2381089-83-2

    1 MT Oct 16, 2024
    United States

    Retatrutide 99% High Quality CAS 2381089-83-2

    1 G Jan 23, 2026
    United States

    Injection Peptide Tirzepatide/Retatrutide/ Semaglutide Peptides CAS 2381089-83-2

    10  Oct 21, 2023
    Palestine

    Factory 99% Purity Retatrutide Peptide CAS 2381089-83-2 Door-To-Door Service

    10 MG Mar 16, 2026
    United States

    Factory 99% Purity Retatrutide Peptide CAS 2381089-83-2 Door-To-Door Service

    20 MG Feb 4, 2026
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