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High Quality Raw Material Amantadine Powder CAS 768-94-5 1-Adamantamine

Name: High Quality Raw Material Amantadine Powder CAS 768-94-5 1-Adamantamine
Brand: TNJONE
SKU: pr2408081091
Price: 30 USD
Availability: InStock

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CAS No.:

768-94-5

Grade:

Pharmaceutical Grade

Content:

98%

Port:

china any port

Brand:

TNJONE

Packaging:

1kg ,25kg or according to customer's detail requirement.

Price valid (until):

2025-11-25

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Shaanxi TNJONE Pharmaceutical Co., Ltd

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

5 days

Qualification:

Main Products:

Semaglutide,Tirzepatide,API,Vitamins,Food Additive

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Product Description
Seller Information

Description

High Quality Raw Material Amantadine Powder CAS 768-94-5 1-Adamantamine

What is Amantadine /1-Adamantamine ?

Amantadine is an antiviral and anti Parkinson's disease drug.
The anti Parkinson's disease mechanism of this product is mainly to promote the synthesis and release of dopamine in the striatum, reduce the reuptake of dopamine by nerve cells, and have anti acetylation

Items	Specifications
Product Name	Amantadine /1-Adamantamine
CAS No.	768-94-5
Appearance	white powder
Assay	98%
MF	C10H17N
MW	151.25
Melting Point	206-208 °C(lit.)
Boiling Point	263.29°C (rough estimate)
Density	0.9510 (rough estimate)

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Certification

Technical Date Sheet:

Items	Standard	Results
Characters	White crystalline powder	Qualified
Identification	Meets the requirements	Qualified
Appearance of solution	Meets the requirements	Qualified
Organic volatile impurities	Meets the requirements	Qualified
Heavy metals	≤0.002%	Qualified
Loss on drying	≤0.5%	0.20%
Residue on ignition	≤0.1%	0.03%
Assay	98.0% ~ 102.0%	99.23%
CONCLUSION:	This is certify that the product complies to the standards

It is absorbed rapidly and completely in gastrointestinal tract and distributed in saliva and nasal secretion. The content in animal tissues, especially in the lungs, was higher than that in serum. This product can pass through placenta and blood-brain barrier. The half-life of normal renal function is 11~15 hours, and that of renal failure is 24 hours. Long-term dialysis patients can reach 7~10 days. 2~4 h after oral administration, the peak blood concentration was about 0.3 g/ml. The steady-state concentration was 0.2~0.9 g/ml within 2~3 days. Mainly excreted by the kidneys. More than 90% of the patients were discharged with urine after glomerular filtration in their original shape, and some of them could be reabsorbed passively. Excretion rate can be rapidly increased in acidic urine; A small amount is also excreted from milk. Only a small percentage (about 4%) of patients on hemodialysis are cleared from blood.

Application:

Applicable to primary Parkinson's disease, Parkinson's syndrome after encephalitis, drug-induced extrapyramidal reaction,
amantadine
amantadine
Parkinson's syndrome after carbon monoxide poisoning and the elderly with cerebral arteriosclerosis of Parkinson's syndrome. Can also be used to prevent or treat armour - Asia. respiratory tract infection caused by influenza viruses. When used in combination with inactivated influenza a virus vaccine, prophylactic antibodies are produced

Company Information

Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital of Xi 'an, is committed to pharmaceutical raw materials, kill varieties, food and feed additives, chemical reagents, plant extracts and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products. Our company after careful planning, hard study, gradually formed a complete service system, based on the domestic and foreign raw materials market special development. Make the raw materials industry bigger and stronger, and serve the vast number of new and old customers. With "world peace and health" as its responsibility, the company adheres to the service concept of "meeting all requirements of customers for products", and guarantees the service principle of "providing qualified products", so that you can get the "God-like" noble shopping enjoyment. Our company has more than 500 kinds of raw materials inventory at any time to meet the various needs of customers for products. The company's products all comply with the relevant national regulations, from the smallest packaging to tons of goods are available. Is your choice of raw materials the best partner.

Shaanxi TNJONE Pharmaceutical Technology Co., Ltd. is willing to rely on the rapid development of e-commerce and national policy support of the good environment background, nesting, welcome people from all walks of life to visit our company, exchange, and seek common development, looking forward to sharing with you, win-win, to realize the dream.

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FAQ

1.How to get in touch with us?

You can chat with us by Trademanager,WhatsApp or simply giving us an email, a phone call. All our contacts information can be found from our website.

2.Are you a manufacturer or trade company?

We are a professional manufacturer.

3.Can I get a sample?

Yes, free sample can be provided, but shipping cost is covered by your side.

4.What's your MOQ?

It is based on the different product. Some are 1g while some are 1 kg. Please be free to consult our salesman.

5.When can I get the quotation?
We usually quote within 1 hours after we get your inquiry. If it's a urgent order you can call us or mention it in your email subject, and we can take it as priority.

6.Is there any discount?
Yes, some products are applied for discount, but it depends on the quantity.

7.Can you do OEM for me?
Yes,we accept OEM orders, just contact us and give us your requirement. We will offer you a reasonable price and make samples ASAP.

ECHEMI Editorial Reference

White to cream powder
Solid
Amantadine is a member of the class of adamantanes that is used as an antiviral and antiparkinson drug. It has a role as an antiviral drug, an antiparkinson drug, a dopaminergic agent, an analgesic, a NMDA receptor antagonist and a non-narcotic analgesic. It is a primary aliphatic amine and a member of adamantanes. It is a conjugate base of an adamantan-1-aminium. It derives from a hydride of an adamantane.|An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.|Amantadine is an Influenza A M2 Protein Inhibitor. The mechanism of action of amantadine is as a M2 Protein Inhibitor.|Amantadine is a primary amine that has both antiviral and dopaminergic activity and is used in the therapy of influenza A and management of Parkinson disease. Amantadine has not been associated with clinically apparent liver injury.|Amantadine is a synthetic tricyclic amine with antiviral, antiparkinsonian, and antihyperalgesic activities. Amantadine appears to exert its antiviral effect against the influenza A virus by interfering with the function of the transmembrane domain of the viral M2 protein, thereby preventing the release of infectious viral nucleic acids into host cells. Furthermore, this agent prevents virus assembly during virus replication. Amantadine exerts its antiparkinsonian effects by stimulating the release of dopamine from striatal dopaminergic nerve terminals and inhibiting its pre-synaptic reuptake. This agent may also exert some anticholinergic effect through inhibition of N-methyl-D-aspartic acid (NMDA) receptor-mediated stimulation of acetylcholine, resulting in antihyperalgesia.

Certificates

Basic Info

Product Name:

Amantadine

Other Name:

Tricyclo[3.3.1.13,7]decan-1-amine;1-Adamantanamine;Amantadine;1-Aminoadamantane;1-Adamantamine;Adamantylamine;1-Adamantylamine;1-Amantadine;Adamantamine;Adamantanamine;NSC 341865;Tricyclo[3.3.1.13,7]decane-1-amine;(Adamantan-1-yl)amine;744952-70-3

CAS No.:

768-94-5

Molecular Formula:

C10H17N

InChIKeys:

InChIKey=DKNWSYNQZKUICI-UHFFFAOYSA-N

Molecular Weight:

151.25

Exact Mass:

151.25

EC Number:

212-201-2

UNII:

BF4C9Z1J53

NSC Number:

341865

DSSTox ID:

DTXSID8022117

NCI Thesaurus Code:

C61632

Color/Form:

HEXAKISTETRAHEDRAL CRYSTALS BY SUBLIMATION

ATC Code:

N04BB01|N - Nervous system

HScode:

29213000

Categories:

Other Chemical Drugs

Characteristics

PSA:

XLogP3:

2.3

Appearance:

White to cream Powder

Density:

1.1±0.1 g/cm3

Melting Point:

180 °C

Boiling Point:

225.7±8.0 °C at 760 mmHg

Flash Point:

96.0±9.7 °C

Refractive Index:

1.558

Water Solubility:

soluble in organic solvents. Insoluble in water.1 M HCl: soluble 5%, clear to hazy, colorless to faint yellow or tan

Storage Conditions:

Store in a cool, dry location. Keep containers tightly sealed.

Vapor Pressure:

0.13 mm Hg at 25 deg C (est)

Toxicity:

LD50 oral in rat: 900mg/kg

Henrys Law Constant:

Henry's Law constant = 8.3X10-6 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

pKa = 10.45 (est)

Experimental Properties:

ODORLESS; BITTER TASTE; DOES NOT MELT UP TO 300 °C, BUT SUBLIMES SLOWLY; PKA: 10.36 AT 30 °C; PH (1 IN 5 SOLN) BETWEEN 3.0 & 5.5. WHITE OR NEARLY WHITE CRYSTALLINE POWDER; 1 G IN 2.5 ML WATER, 5.1 ML ALCOHOL, 18 ML CHLOROFORM, 70 ML POLYETHYLENE GLYCOL 400 /AMANTADINE HYDROCHLORDIE/|Hydroxyl radical reaction rate constant = 4.0X10-11 cu cm/molecule-sec at 25 °C (est)

See More Amantadine Properties 

Hazard Identification

Classification of the substance or mixture

Flammable liquids, Category 3

Acute toxicity - Category 4, Oral

Acute toxicity - Category 4, Dermal

Skin corrosion, Sub-category 1B

Serious eye damage, Category 1

Acute toxicity - Category 4, Inhalation

Reproductive toxicity, Category 2

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H226 Flammable liquid and vapour H302 Harmful if swallowed H312 Harmful in contact with skin H314 Causes severe skin burns and eye damage H332 Harmful if inhaled H361 Suspected of damaging fertility or the unborn child H402 Harmful to aquatic life H412 Harmful to aquatic life with long lasting effects
Prevention	P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P233 Keep container tightly closed. P240 Ground and bond container and receiving equipment. P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment. P242 Use non-sparking tools. P243 Take action to prevent static discharges. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P203 Obtain, read and follow all safety instructions before use. P273 Avoid release to the environment.
Response	P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower]. P370+P378 In case of fire: Use ... to extinguish. P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P317 Get medical help. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P363 Wash contaminated clothing before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P316 Get emergency medical help immediately. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P318 IF exposed or concerned, get medical advice.
Storage	P403+P235 Store in a well-ventilated place. Keep cool. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Amantadine Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Semaglutide,Tirzepatide,API,Vitamins,Food Additive

Location:
No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New City, Xi 'an, Shaanxi Province

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
5 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2019

Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital Xi 'an, is committed to the peptide industry, pharmaceutical raw materials, food and feed additives, veterinary drugs and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products, "world peace and health" as its responsibility, the company adhering to the "meet all customer requirements for products" as the service concept, Guarantee "provide qualified products" as the service principle, so that you get "God-like" noble shopping enjoyment. Our company has more than 1000 kinds of polypeptides, raw materials inventory, at any time to meet the various needs of customers for products. Is your best partner.
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High Quality Raw Material Amantadine Powder CAS 768-94-5 1-Adamantamine

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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