Fezolinetant CAS 1629229-37-3 high quality can be supplied from stock
2 Inquiries
1629229-37-3
Pharmaceutical Grade
99%
Million
25kg/Cardboard Drum
Yes
2024-09-13
Apixaban Repotrectinib/TPX-0005,Edoxaban,Lurasidone,Elacestrant,Bexagliflozin,Baricitinib
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceFezolinetant is under investigation in clinical trial NCT04234204 (A Study to Find Out if Fezolinetant Helps Reduce Moderate to Severe Hot Flashes in Women in Asia Going Through Menopause).
ChEBI: Fezolinetant is a triazolopyrazine that is 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine substituted by 3-methyl-1,2,4-thiadiazol-5-yl, 4-fluorobenzoyl and methyl groups at positions 3, 7, and 8R, respectively. It is a prescription medicine used to reduce moderate to severe vasomotor symptoms due to menopause. It has a role as a neurokinin-3 receptor antagonist. It is a member of monofluorobenzenes, a triazolopyrazine, a member of thiadiazoles, a member of benzamides and a tertiary carboxamide.Basic Info-
Product Name:
Fezolinetant
Other Name:FEZOLINETANT; ESN-364; ESN 364; ESN364;ESN-364;Methanone, [(8R)-5,6-dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)-;Inhibitor,Neurokinin Receptor,ESN364,Tachykinin receptor,ESN 364,Fezolinetant,inhibit,NK receptor;(R)-(4-fluorophenyl)(8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone;Fexolinetant;Fezolinetant;(S)-1-((2-((tert-butyldimethylsilyl)oxy)ethyl)amino)-2,3-dihydro-1H-indene-4-carbonitrile
CAS No.:1629229-37-3
Molecular Formula:C16H15FN6OS
InChIKeys:PPSNFPASKFYPMN-SECBINFHSA-N
Molecular Weight:358.39
Exact Mass:358.10120846
UNII:83VNE45KXX
Color/Form:White to yellow
Categories:
Characteristics-
Density:
1.56±0.1 g/cm3(Predicted)
Boiling Point:623.0±65.0 °C(Predicted)
PKA:-0.28±0.40(Predicted)
Critical Temperature & Pressure:Store at -20°C
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Seller Information
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Business Type:
Trader
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Main Products:
Apixaban Repotrectinib/TPX-0005,Edoxaban,Lurasidone,Elacestrant,Bexagliflozin,Baricitinib
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Location:
Room1-2208,Lianhecaifu Square,No2177,Tianchen road,Gaoxin district
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Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
3 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2012
Company Certificates-
certification of high-tech enterprise
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted
Pakistan
FEZOLINETANT
450 G Feb 14, 2025
Bangladesh
Fezolinetant
50 KG Dec 31, 2024 Post an enquiry for this product
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Fezolinetant is an oral small molecule neurokinin-3 receptor (NK3R) antagonist developed by Astellas Pharma Inc. for the treatment of moderate to severe vasoconstrictive symptoms (VMS) or menopausal hot flashes. Fezolinetant is a non hormonal strategy that regulates neuronal activity related to temperature regulation by inhibiting NK3R mediated signaling in the central nervous system, thereby reducing the frequency and severity of VMS.


