TNJONE Factory Supply High Quality Raw Material Topilutamiden CAS 260980-89-0

Topilutamide, known more commonly as fluridil and sold under the brand name Eucapil, is an antiandrogen medication which is used in the treatment of pattern hair loss in men and women. It is used as a topical medication and is applied to the scalp. Topilutamide is a nonsteroidal antiandrogen (NSAA), or an antagonist of the androgen receptor (AR), the biological target of androgens like DHT. Topilutamide was introduced for medical use in 2003.

Name	Topilutamide
CAS NO.	260980-89-0
purity	99%
Standard packing material	Bag/Box
Appearance	white Powder
Shelf Life	2Years
storage condition and solubility	Inert atmosphere,2-8°C; soluble in water

Item	Standard	Result
Appearance	White or almost white crystalline powder	Almost white crystalline powder
Melting point	152-156°C	154.6-155.1°C
Specific optical rotation	-16° to -19°	-17.5°
Identification	(1)The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation,as obtained in the assay.	Complies
	(2)UV absorption Max. at 266nm.	Complies
	(3)IR spectra is consistent with CRS.	Complies
PH	4.5-6.5	5.7
Chloride	0.02% max	<0.02%
Fluorides	4.8%min	4.9%
Related substances	Individual impurity not more than 0.5%	0.35%
	Total impurities not more than 2.0%	0.76%
Water	0.5% max	0.13%
Residue on ignition	0.1%max	0.06%
Heavy metals	Less than or egual to 20 millionths	Less than20 millionths
Assay(C12H14Cl2FNO4S)	98.0%min	99.0%

Function&Application:

• Prostatecanceristhemostcommoncancerandoneoftheleadingcausesofcancerdeathsinmen.OneofthecommonlyusedapproachestotreatmetastatiChemicalbookcprostatecancerisviafirst-generationnonsteroidalanti-androgens(NSAAs),namelyFlutamide,Nilutamide,BicalutamideandTopilutamide.

Shaanxi TNJONE Pharmaceutical Co., Ltd is a high-tech enterprise mainly engaged inthe development and sale of pharmaceutical chemical raw materials and relatedproducts.The company has advanced and perfect supporting system,forming advancedchemical synthesis technology, which can quickly meet the individual needs and serialdevelopment from suitable detection to industrial production.Qur business covers morethan 30 countries, most of customers from Europe, Southeast Asia and other countriesin the world, we can guarantee the quality and price. Our enterprise purpose is basedon the market, strengthen strength, take the road of scientific environmental protectionand sustainable development, rely on the country. The company has a strong financialstrength and a good business environment, can provide customers with quality,efficientand fast service.

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