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TTX

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CAS No.:

4368-28-9

Port:

SHANGHAI

Packaging:

BAG

Price valid (until):

2024-09-23

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Shaanxi Dideu Medichem Co. Ltd

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

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Product Description
Seller Information
Inquiry History

Description

Tetrodotoxin, scientifically known as tetrodotoxin (TTX), is a natural sodium channel blocker (S1SCB) that blocks the passageway on the cell membrane to prevent information transmission. It is this particularity that makes pufferfish so "lethal"! Once you eat its toxic meat by mistake, the release of the toxin with super strong endurance can cause paralysis of the diaphragm, leading to suffocation and death. The toxin contained in pufferfish is a complex compound of polyhydroxy perhydromethylquinazoline. The elemental composition is approximately C10-12H15-19O8-10N3, weakly alkaline, and colorless crystals. The lethal dose LD50 for mice is 5×10-9—10×10-9, and 0.3 mg will kill a person of medium weight within 1-2 hours. Tetrodotoxin is generally found in the blood, ovaries, skin, and liver. However, the muscles of the two-spot pufferfish also contain strong toxins, and the dark-colored pufferfish has the strongest kidney toxicity. The toxicity of pufferfish varies with the season, and is strongest in winter and spring. The toxicity of young fish is no less than that of adult fish. Pufferfish toxin is stable, and salting, sun exposure, and normal cooking cannot detoxify it. If it is mixed with non-toxic fish, the non-toxic fish can also be contaminated by its toxin. Pufferfish toxin acts on the nerve center and can cause respiratory and circulatory failure. Product Detail

Basic Info

Product Name:

Tetrodotoxin

Other Name:

5,9:7,10a-Dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol,2-amino-1,4,4a,5,9,10-hexahydro-12-(hydroxymethyl)-,(4R,4aR,5R,7S,9S,10S,10aR,11S,12S)-;Tetrodotoxin;8a(1H)-Quinazolineorthoglycolic acid,octahydro-4,5,6,7,8-pentahydroxy-6-(hydroxymethyl)-2-imino-,cyclic 8a,5:8a,7-ester;(4R,4aR,5R,7S,9S,10S,10aR,11S,12S)-2-Amino-1,4,4a,5,9,10-hexahydro-12-(hydroxymethyl)-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol;Tarichatoxin;Spheroidine;5,9:7,10a-Dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol,octahydro-12-(hydroxymethyl)-2-imino-,[4R-(4α,4aα,5α,7α,9α,10α,10aβ,11S*,12S*)]-;Maculotoxin;Tetrodotoxine;[4R-(4α,4aα,5α,7α,9α,10α,10aβ,11S*,12S*)]-Octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol;BJT 1;Babyloniajaponica toxin 1;Araregai toxin;TTX;(-)-Tetrodotoxin;PFT-1 Toxin;Tectin;2229-61-0;9014-39-5;11005-69-9;11026-09-8;12626-86-7;17289-88-2;954370-68-4;2244057-51-8

CAS No.:

4368-28-9

Molecular Formula:

C11H17N3O8

InChIKeys:

InChIKey=CFMYXEVWODSLAX-HUILCFQTSA-N

Molecular Weight:

319.27

Exact Mass:

319.27

EC Number:

224-458-8

Color/Form:

Crystals

HScode:

30029090

Categories:

Antineoplastic Agents

Characteristics

PSA:

187.75000

XLogP3:

2.16

Appearance:

white powder

Density:

2.8±0.1 g/cm3

Melting Point:

280 °C (decomp)

Boiling Point:

702.6±70.0 °C at 760 mmHg

Flash Point:

378.7±35.7 °C

Refractive Index:

2.087

Water Solubility:

H2O: stable at pH 4-5 if stored frozensoluble

Storage Conditions:

2-8°C

Toxicity:

Oral-Mouse LD50: 0.334 mg/kg; Intravenous-Mouse LD50: 0.007 mg/kg

Flammability characteristics:

Flammable, decomposes toxic nitrogen oxide gas when burning

Specific rotation:

D25 -8.64° (c = 8.55 in dil acetic acid)

Dissociation Constants:

pKa: 8.76 (water), 9.4 (50% alcohol)

Experimental Properties:

Darkens above 220 °C without decomposition ... toxin /is/ destroyed in strong acids and in alkaline solutions.|... heat-stable (except in alkaline milieu), water-soluble ... unstable when heated to 100 °C (212 °F) in acid ... can be fatal when ingested|Hydroxyl radical reaction rate constant = 3.71X10-10 cu cm/molec-sec at 25 °C (est)

See More Tetrodotoxin Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 2, Oral

Acute toxicity - Category 2, Dermal

Acute toxicity - Category 1, Inhalation

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H300 Fatal if swallowed H310 Fatal in contact with skin H330 Fatal if inhaled
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P262 Do not get in eyes, on skin, or on clothing. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P260 Do not breathe dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P284 [In case of inadequate ventilation] wear respiratory protection.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P316 Get emergency medical help immediately. P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P320 Specific treatment is urgent (see ... on this label).
Storage	P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Tetrodotoxin Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

Location:
https://www.dideu.com/en/

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7

Total Annual Revenue:
Above $100 million

Total Employees:
Above 1000

Year of Establishment:
2016

Certifications:
ISO Certificate,REACH

Company Profile

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
Israel	TTX	1 G	Aug 23, 2024

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TTX

Product Description

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