High Purity Factory Price Organic Intermediate Apixaban Powder CAS 503612-47-3 Apixaban

                                           -Product Descrition-

Test Items	Specifications	Test Results
Appearance	White powder	White powder
Purity by HPLC	≥99%	99.21%
Single impurity	≤0.1%	0.08%

PORDUCT DRTAILS

Product name	Apixaban
Appearance	White powder
Cas number	503612-47-3
MF	C25H25N5O4
MW	459.506

Apixaban is a highly selective, reversible, and direct inhibitor of Human Factor X and Rabbit Factor X with Ki of 0.08 nM and 0.17 nM, respectively. Apixaban exhibits a high degree of potency, selectivity, and efficacy on Factor X with Ki of 0.08 nM and 0.17 nM for Human Factor X and Rabbit Factor X, respectively. In vitro, Apixaban prolongs the clotting times of normal human plasma with the concentrations (EC2x) of 3.6 μM, 0.37 μM, 7.4 μM, and 0.4 μM, which are required respectively to double the prothrombin time (PT),modified prothrombin time (mPT), activated partial thromboplastin time (APTT) and HepTest. Besides, Apixaban shows the highestpotency in human and rabbit plasma, but less potency in rat and dog plasma in both the PT and APTT assays.

Function of apixaban
1. Apixaban is used for reducing the risk of blood clots in the heart and strokes in patients with atrial fibrillation who have no problems with their heart valves (nonvalvular atrial fibrillation)
2. Apixaban used for treating and preventing deep venous thrombosis (DVT) and pulmonary embolism in patients who have undergone hip or knee replacement surgery.
Application of apixaban
1) Apixaban is factor Xa inhibitor anticoagulant indicated to reduce the risk of stroke.
2) Apixaban also have effect i systemic in patients with nonvavular atrial fibrillation.

General: Apixab is a potent, orally active, reversible, direct, and highly selective factor Xa active site inhibitor with antithrombotic activity. It inhibits free and thrombus-bound factor Xa and inhibits prothrombin activity. Apixab is an anticoagulant used to prevent venous thromboembolism and atrial fibrillation stroke. It is a direct factor Xa inhibitor. Apixab can be used for antithrombotic therapy in patients with acute coronary syndrome (ACS) and percutaneous coronary intervention (PCI) of atrial fibrillation.

Function：Apixabcan prevent thrombin generation and thrombosis, and play an anticoagulant role by inhibiting coagulation factor Xa.

Drug efficacy: Apixab is the third new oral anticoagulan. It has been approved in Europe to prevent venous thromboembolic events in patients undergoing elective hip or knee replacement surgery.

Superiority

1.High quality and competitive price.
2.Free sample for your evaluation.
3.Promptly delivery by well-reputed shipping lines.
4.We will inform you all the information at every stage in advance.
5.Packaging can gear to buyers’ special request. 

Our service

1. Reply your inquiry in 24 working hours.
2. Customized design is available. OEM are welcomed.
3. Exclusive and unique solution can be provided to our customer by our well-trained and professional engineers and
staff.
4. As an honest seller, we always use superior raw material, advanced machines, skilled technicians to ensure our products to be finished in high quality and stable feature.

Why Choose Us?

1. High-concentration products, strictly control the quality.
2. Reasonable and flexible price matched with high quality.
3. Spot samples can be shipped quickly after payment, saving time for receiving goods.
4.Full experience of large numbers containers loading in Chinese sea port.
5. Safe raw materials from China.
6. Have professional customs clearance capabilities and the best after-sales service.

1. Pharmaceutical Expertise:

• With years of experience in the pharmaceutical industry, our team brings extensive expertise in product development, manufacturing, and distribution.

2. High-Quality Products:

• We adhere to stringent quality control standards and Good Manufacturing Practices (GMP) to ensure the safety and efficacy of our pharmaceutical products.

3. Diverse Product Range:

• Our extensive product portfolio includes Active Pharmaceutical Ingredients (APIs), finished dosage forms, pharmaceutical intermediates, and customized pharmaceutical solutions to meet a wide range of needs.

4. Customization Capabilities:

• We offer tailored solutions for pharmaceutical product development and manufacturing to meet the unique requirements of our clients.

5. Global Reach:

• We have a strong international presence, allowing us to serve customers and partners worldwide. Our products are distributed in various regions, ensuring accessibility and reliability.

6. Regulatory Compliance:

• We maintain strict adherence to international regulatory standards and guidelines, ensuring that our products meet all necessary regulatory requirements.

7. Responsive Customer Support:

• Our dedicated customer support team is available to assist you promptly with inquiries, orders, and technical support.

8. Competitive Pricing:

• We strive to provide competitive pricing for our high-quality pharmaceutical products, enabling cost-effective solutions for our clients.

9. Sustainable Practices:

• We are committed to environmentally responsible practices in our manufacturing processes and operations, contributing to a sustainable future.

10. Innovation and Research: - We invest in research and development to stay at the forefront of pharmaceutical advancements and deliver innovative products to our customers.

11. Long-Term Partnerships: - We value long-term relationships with our customers and partners, fostering trust and collaboration for mutual success.

12. Transparent Communication: - We believe in transparent and open communication, ensuring that our clients are informed and confident in their dealings with us.