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Dinoprost tromethamine 99%

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Unit Price:

$222-223/G FOB

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CAS No.:

38562-01-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

SHANGHAI

Packaging:

1G 5G 55G

Price valid (until):

2029-06-29

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Chong Da Prostaglandin Fine Chemicals Co., Ltd

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

prostaglandins,Polymyxin B sulfate,Clemizole hydrochloride,1,4-Diacetylbenzene,Estradiol valerate ,IMD 0354

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Product Description
Seller Information
Inquiry History

Description

Product Detail

I tems	S pecifications	Results
Appearance	White or off- white powder	off- white powder
Identification (IR)	The IR spectrum of the sample exhibits maximun only at the same wavelength as that similar preparation of USP Dinoprost Tromethamine RS	Conforms
Solubility	Very soluble in water,freely soluble in ethanol(96%),practically insoluble in acetonitrile	Conforms
Optical rotation	+19 ° ~ +26 °	+23. 4 °
Loss on drying	N.M.T 1.0%	0.1 7 %
Residue on ignition	N.M.T 0.5%	0. 08 %
W ater	N.M.T 1.0%	0.20%
Residual solvents	Ethyl acetate: N.M.T. 5000ppm	N.D
	Acetone : N.M.T. 5000ppm	1033ppm
	Acetontrile : N.M.T. 410ppm	N.D
	Ethanol : N.M.T. 5000ppm	N.D
	Methanol : N.M.T. 3000ppm	N.D
	Terahydrofuran : N.M.T. 720ppm	N.D
Chromatographic Purity	Impurity A : N.M.T. 2.0 %	1. 2%
	Impurity B : N.M.T. 1 . 5 %	N.D
	Any unspecified impurity: N.M.T. 0.10%	0. 17 %
	Total other impurities: N.M.T. 2.0 %	0.40%
Assay	95.0~105.0%( calculated on the dried basis)	9 7.6 %

Dinoprost tromethamine salt (Prostaglandin F2α tromethamine salt) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost tromethamine salt is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost tromethamine salt plays a key role in the onset and progression of labour^[1] ^[2].

[1]. Hagen Thieme, et al. Endothelin antagonism: effects of FP receptor agonists prostaglandin F2alpha and fluprostenol on trabecular meshwork contractility. Invest Ophthalmol Vis Sci. 2006 Mar;47(3):938-45.

[2]. Xin Wen, et al. Prostaglandin F2α Induces Goat Corpus Luteum Regression via Endoplasmic Reticulum Stress and Autophagy. Front Physiol. 2020 Sep 11;11:868.

Basic Info

Product Name:

Dinoprost tromethamine

Other Name:

Prosta-5,13-dien-1-oic acid,9,11,15-trihydroxy-,(5Z,9α,11α,13E,15S)-,compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1);1,3-Propanediol,2-amino-2-(hydroxymethyl)-,(5Z,9α,11α,13E,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oate (salt);Prostaglandin F2α THAM salt;Prostaglandin F2α tromethamine salt;Prostaglandin F2α tromethamine;THAM PGF2α;Tromethamine prostaglandin F2α;PGF2α THAM;PGF2α THAM salt;PGF2α tromethamine salt;Prostaglandin F2α tris(hydroxymethyl)aminomethane salt;U 14585;PGF2α Tris salt;Prostaglandin F2α-tham;PGF2α tromethamine;Dinoprost tromethamine;Lutalyse;U 14583E;Minprostin F2α;Prostaglandin F2α tris(hydroxymethyl)aminomethane;Dinolytic;Pronalgon F;Prostaglandin F2a tromethamine salt;NSC 196515;Lutalyze;Enzaprost T;Dinoprost trometamol;36300-07-9;38473-38-0;51553-13-0

CAS No.:

38562-01-5

Molecular Formula:

C20H34O5.C4H11NO3

InChIKeys:

InChIKey=IYGXEHDCSOYNKY-RZHHZEQLSA-N

Molecular Weight:

475.62

Exact Mass:

475.314514

EC Number:

254-002-3

HScode:

2937500000

Categories:

Other Chemical Drugs

Characteristics

PSA:

185

Appearance:

white powder

Melting Point:

25-35 °C

Boiling Point:

531°C

Flash Point:

289ºC

Water Solubility:

H2O: 1 mg/mL Aqueous solutions are stable for 30 days at 2-8°C and for several months frozen at −0°C in single use aliquots. Avoid repeated freeze/thaw cycles.

Storage Conditions:

−20°C

See More Dinoprost tromethamine Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Reproductive toxicity, Category 1B

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H302 Harmful if swallowed H360 May damage fertility or the unborn child
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Dinoprost tromethamine Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
prostaglandins,Polymyxin B sulfate,Clemizole hydrochloride,1,4-Diacetylbenzene,Estradiol valerate,IMD 0354

Location:
NO.1585 JIUYE ROAD, QINGPU DISTRICT, SHANGHAI, CHINA

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,100% TT in advance

Average lead Time:
7

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2011

Certifications:
ISO9001

Company Profile

Founded in 2018, Shanghai Chong Da Prostaglandin Fine Chemicals Co., Ltd. is a professional manufacturer committed to research, development and promotion of prostaglandin(PG) in both human medicine and animal health. The company also has a technical team with decades of experience in PG production.
Chong Da now has mature technology with a complete production chain, laboratory analysis system and strict product management mode,are responsible for sales as well as experiments and development of new products .
Our products are exported to more than 20 countries and regions, mainly in South America and Europe. The main products are: Cloprostenol Sodium, Latanoprost, Bimatoprost, Travoprost, Prostaglandin E1, E2, etc., and related derivatives, intermediates and extraction of impurities appearing in the production process.

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
United Kingdom	Dinoprost Tromethamine	1 G	May 29, 2026

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