API Diclofenac sodium

Name

Diclofenac sodium

CAS number

15307-79-6

Synonym

Abitren, Allvoran, Assaren, Batafil, Berifen, Blesin, Delimon, Delphimix, Diclofenac sodium, Neriodin, Orthophen, Sodium diclofenac, Voltaren, Voltaren-XR, Voltarene, Voltarol

Related CAS #

81811-14-5 (deanol);119623-66-4 (epolamine);15307-86-5 (free acid);15307-79-6 (sodium);15307-81-0 (Potassium);78213-16-8 (diethylamine);64118-81-6 (Acyl Glucuronide) 

Description

 Diclofenac sodium is a widely used non-steroidal anti-inflammatory drug (NSAID).

Uses

It is commonly employed to relieve pain, reduce inflammation, and lower fever. It is effective in treating various conditions such as arthritis, muscle pain, back pain, menstrual cramps, and headaches.

Mechanism of action:

Diclofenac sodium works by inhibiting the activity of cyclooxygenase (COX) enzymes. There are two types of COX enzymes, COX-1 and COX-2. By inhibiting these enzymes, it reduces the production of prostaglandins, which are chemicals that cause pain and inflammation.

Dosage and administration

The dosage of diclofenac sodium depends on the condition being treated, the patient's age, weight, and overall health. It is available in different forms such as tablets, capsules, gels, and injections. It is usually taken orally with or without food. Topical forms can be applied directly to the affected area.

Side effects

Like all medications, diclofenac sodium can cause side effects. Common side effects include stomach pain, nausea, vomiting, diarrhea, indigestion, and headache. More serious side effects may include stomach ulcers, bleeding, liver damage, kidney problems, and allergic reactions.

Precautions

People with a history of stomach ulcers, bleeding disorders, liver or kidney disease, heart problems, or high blood pressure should use diclofenac sodium with caution. It should also be used carefully in the elderly and in those taking other medications that may increase the risk of side effects. Pregnant and breastfeeding women should consult a doctor before using this drug.

In conclusion, diclofenac sodium is an important NSAID that can provide effective relief from pain and inflammation. However, it should be used carefully and under the supervision of a healthcare professional to minimize the risk of side effects.

Structure

Molecular Formula

C₁₄H₁₀Cl₂NNaO₂

Molecular Weight

318.130

Appearance

Solid powder

Quality Standard

Enterprise standard

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0~4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Shelf Life

>3 years if stored properly

Sample package

Aluminium foil bag

Commercial package

Aluminium Tin, Fiber drum

Origin

China