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Supply High Quality White Powder Indole-3-carbinol CAS 700-06-1 I3C for Cancer Prevention

Name: Supply High Quality White Powder Indole-3-carbinol CAS 700-06-1 I3C for Cancer Prevention
Brand: HyperChem
SKU: pr2410161291
Price: 80 USD
Availability: InStock

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CAS No.:

700-06-1

Grade:

Pharmaceutical Grade

Content:

99%

Port:

SHANGHAI

Brand:

HyperChem

Packaging:

1kg/Bag, 25kg/drum

Price valid (until):

2024-11-16

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information
Inquiry History

Description

Name	Indole-3-carbinol
CAS number	700-06-1
EINECS number	200-258-6
Synonym	Indole-3-carbinol; I3C; 3-Indolemethanol; 1H-Indol-3-ylmethanol
Description	Indole-3-carbinol (I3C) is a natural anti-cancer phytochemical derived from the breakdown of glucobrassicin, a glucosinolate found in cruciferous vegetables such as broccoli, cabbage, cauliflower, and kale. It is produced through the action of myrosinase on glucobrassinin, a glucosinolate found in these vegetables. I3C has been extensively studied for its potential health benefits, particularly in the context of cancer prevention and treatment. It exhibits anti-cancer properties by inhibiting the growth of various cancer cell lines, including hepatocellular carcinoma, nasopharyngeal carcinoma, and breast cancer cells. These effects are attributed to its ability to inhibit key signaling pathways such as NF-κB and PI3K/Akt, which are involved in cell proliferation and survival. Additionally, I3C can induce cell cycle arrest at the G1 phase and promote apoptosis (programmed cell death).
Structure
Molecular Formula	C9H9NO
Molecular Weight	147.17 g/mol
Appearance	Solid powder
Quality Standard	Enterprise Standard
Assay	≥98%
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Store in tightly closed plastic bag below 4℃ in dry place.
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Aluminium Tin, Fiber drum
Origin	China
HS Code	2933990099

Indole-3-carbinol More Info

Indole-3-carbinol (I3C) is a naturally occurring compound derived from the breakdown of glucobrassicin, a glucosinolate found in cruciferous vegetables such as broccoli, cabbage, cauliflower, and kale. This compound has garnered attention for its potential health benefits, particularly in cancer prevention and treatment.

Mechanism of Action

The anticancer effects of I3C are multifaceted:
1. Cell Cycle Regulation: I3C induces G1 phase arrest in the cell cycle, which is crucial for inhibiting the proliferation of cancer cells. This effect has been observed in various cancer types, including breast and prostate cancers.
2. Gene Expression Modulation: I3C influences microRNA expression and upregulates apoptotic enzymes, contributing to its antiproliferative effects.
3. Estrogen Modulation: It exhibits anti-estrogenic properties, which may be beneficial for hormone-sensitive cancers by modulating estrogen receptor activity.
4. Detoxification Enhancement: I3C stimulates detoxifying enzymes in the liver and gut, potentially aiding in the elimination of carcinogens.

Applications

I3C is primarily studied for its potential applications in:
1. Cancer Prevention: It may help prevent breast, cervical, endometrial, and colorectal cancers by inhibiting tumor growth and enhancing the effects of certain chemotherapy drugs.
2. Liver Health: I3C has shown hepatoprotective effects by modulating immune responses and reducing inflammation.
3. Autoimmune Conditions: Preliminary studies suggest it may benefit conditions like systemic lupus erythematosus (SLE) by normalizing T cell function.

4. Antioxidant: It may help in reducing oxidative stress.
5. Anti-inflammatory: I3C has shown potential in modulating inflammatory responses.
6. Anti-estrogenic Effects: This can be particularly beneficial for conditions sensitive to estrogen, such as certain breast cancers

Routes of Administration

I3C can be consumed through:
Dietary Sources: Found naturally in cruciferous vegetables.
Dietary Supplements: Available as capsules or tablets for those seeking higher concentrations than can be obtained through diet alone.

Safety and Side Effects

I3C is generally considered safe when consumed in amounts typically found in food. However, higher doses may lead to side effects such as:
Gastrointestinal Issues: Nausea, diarrhea, and abdominal discomfort.
Neurological Symptoms: Balance problems and tremors have been reported at high doses34.
Hormonal Effects: Since I3C can influence estrogen levels, individuals on hormone therapy should exercise caution

Package Image

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
LC at sight
DP at sight

Bank transfer

PayPal

Bitcoin...

Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express
FedEx UPS DHL EMS
Fast: 3-7 days around, high cost, door to door service

By Air
Suitable for more than 50kg
Fast: 3-7 days, hight cost, port to port, professional broker needed

By Sea
Suitable for more than 500kg
Fast: 7-45 days, low cost, port to port, professional broker needed

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders:
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.

Certificates

Basic Info

Product Name:

Indole-3-carbinol

Other Name:

1H-Indole-3-methanol;Indole-3-methanol;Indole-3-carbinol;3-(Hydroxymethyl)indole;3-Indolylcarbinol;3-Indolylmethanol;NSC 525801;Indinol;1H-Indol-3-ylmethanol;(1H-Indol-3-yl)methanol

CAS No.:

700-06-1

Molecular Formula:

C9H9NO

InChIKeys:

InChIKey=IVYPNXXAYMYVSP-UHFFFAOYSA-N

Molecular Weight:

147.177

Exact Mass:

147.17

EC Number:

211-836-2

UNII:

C11E72455F

NSC Number:

525801

DSSTox ID:

DTXSID7031458

HScode:

2933990090

Categories:

Antineoplastic Agents

Characteristics

PSA:

XLogP3:

1.1

Appearance:

Solid

Density:

1.3±0.1 g/cm3

Melting Point:

90 °C

Boiling Point:

360.6°C at 760 mmHg

Flash Point:

171.9±20.9 °C

Refractive Index:

1.705

Water Solubility:

7 [ug/mL]

Storage Conditions:

2-8ºC

See More Indole-3-carbinol Properties 

Hazard Identification

Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H315 Causes skin irritation H319 Causes serious eye irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Indole-3-carbinol Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Certifications:
Certification Report by Bureau Veritas

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
Turkey	İndole 3 carbinol	25 KG	Feb 14, 2024
Cameroon	Indole-3-Carbinol	10 KG	Oct 16, 2024

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