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Amantadine Hydrochloride 100%

Name: Amantadine Hydrochloride 100%
Brand: HyperChem
SKU: pr2410232301
Price: 50 USD
Availability: InStock

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CAS No.:

665-66-7

Grade:

Pharmaceutical Grade

Content:

100%

Port:

HANGZHOU

Brand:

HyperChem

Packaging:

3/Ctn

Price valid (until):

2024-11-23

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information
Inquiry History

Description

Name	Amantadine Hydrochloride
CAS number	665-66-7
Synonym	ADS-5102; EXP 105-1; EXP-105-1; GP 38026; Influenol; Midantan; Midantane; Mydantane; NSC 83653; Amantadine HCl; Symadine; Symmetrel; Trivaline; Virasol; Viregyt; Virofral; Virosol.
Description	Amantadine is a drug that has U.S. Food and Drug Administration approval for use both as an antiviral and an anti-parkinsonian drug. Amantadine is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake. Amantadine probably does not inhibit MAO enzyme. Moreover, the mechanism of its antiparkinsonian effect is poorly understood.[citation needed] The drug has many effects in the brain, including release of dopamine and norepinephrine from nerve endings. It appears to be a weak NMDA receptor antagonist as well as an anticholinergic, specifically a nicotinic alpha-7 antagonist like the similar pharmaceutical memantine.
Structure
Molecular Formula	C10H18ClN
Molecular Weight	187.711
Appearance	Solid powder
Quality Standard	USP
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Dry, dark and at 2~8 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Fiber ctn
Origin	China

Amantadine Hydrochloride More Info

Amantadine Hydrochloride is a pharmaceutical drug with a variety of clinical applications. It is primarily used in the treatment of Parkinson's disease and for the prophylaxis and treatment of influenza A. The drug works by increasing the release of dopamine in the brain, which helps to alleviate the symptoms of Parkinson's such as tremors and rigidity. Additionally, it inhibits the replication of the influenza A virus by interfering with a viral protein, M2, which is essential for the virus to shed its outer coating and release its genetic material into the host cell.

Uses:

For the treatment of Parkinson's disease, Amantadine Hydrochloride helps to manage the symptoms by facilitating the release of dopamine in the brain.

As an antiviral agent, it is effective in preventing and treating infections caused by influenza A virus, especially when administered within 48 hours of the onset of symptoms.

Precautions:

The drug should be used with caution in patients with a history of seizures, as it may lower the seizure threshold.

It is contraindicated in patients with liver or kidney diseases, and in those with a history of allergic reactions to the drug.

Amantadine Hydrochloride may cause side effects such as dizziness, insomnia, and hallucinations, and therefore, patients should be monitored for these effects, especially the elderly.

It is important to adhere to the prescribed dosage to avoid overdose, which can lead to serious cardiovascular and central nervous system toxicity.

Summary:

Amantadine Hydrochloride is a medication with established efficacy in treating Parkinson's disease and preventing and treating influenza A. However, its use requires careful consideration of potential side effects and contraindications, particularly in patients with pre-existing health conditions. As with any medication, it should be used under the supervision of a healthcare provider.

ECHEMI Editorial Reference

Amantadine Hydrochloride is an antiviral and an antiparkinsonian drug.Target: Influenza VirusAmantadine is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. Amantadine binding of M2, based on studies of a peptide representing the M2 transmembrane segment in dodecylphosphocholine micelles. Amantadine competes with protons for binding to the

Certificates

Basic Info

Product Name:

Amantadine hydrochloride

Other Name:

Tricyclo[3.3.1.13,7]decan-1-amine,hydrochloride (1:1);1-Adamantanamine,hydrochloride;Tricyclo[3.3.1.13,7]decan-1-amine,hydrochloride;Adamantanamine hydrochloride;EXP 105-1;NSC 83653;Symmetrel;Aminoadamantane hydrochloride;Mydantane;Midantane;1-Aminoadamantane hydrochloride;1-Adamantylamine hydrochloride;Adamantylamine hydrochloride;1-Adamantamine hydrochloride;Amantadine hydrochloride;Virasol;Symadine;Amazolon;Mantadine;Virofral;Mantadan;Midantan;Mantadix;Adamin;Adamine;ADS 5102;Gocovri;13878-11-0

CAS No.:

665-66-7

Molecular Formula:

C10H17N.ClH

InChIKeys:

InChIKey=WOLHOYHSEKDWQH-UHFFFAOYSA-N

Molecular Weight:

187.71000

Exact Mass:

187.11300

EC Number:

211-560-2

UNII:

M6Q1EO9TD0

NSC Number:

755860|83653

NCI Thesaurus Code:

C28818

HScode:

2921300090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

26.02000

XLogP3:

3.41620

Appearance:

Crystalline Solid

Density:

1.067g/cm3

Melting Point:

359-360 °C

Boiling Point:

225.7ºC at 760 mmHg

Flash Point:

96ºC

Refractive Index:

1.558

Water Solubility:

H2O: soluble ;Sparingly sol in water

Storage Conditions:

Store in a cool, dry place. Store in a tightly closed container.

Vapor Pressure:

0.13 mm Hg at 25 deg C (est)

Toxicity:

LD50 orally in mice, rats: 700, 1275 mg/kg (Vernier)

Collision Cross Section:

138.6 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

See More Amantadine hydrochloride Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin corrosion, Sub-category 1B

Serious eye damage, Category 1

Reproductive toxicity, Category 2

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H302 Harmful if swallowed H314 Causes severe skin burns and eye damage H361 Suspected of damaging fertility or the unborn child H402 Harmful to aquatic life H412 Harmful to aquatic life with long lasting effects
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P203 Obtain, read and follow all safety instructions before use. P273 Avoid release to the environment.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P363 Wash contaminated clothing before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P316 Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help. P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Amantadine hydrochloride Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Certifications:
Certification Report by Bureau Veritas

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

11 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	1-Adamantanamine hydrochloride	1000 MT	Jan 9, 2026
India	1-Adamantanamine hydrochloride	1000 KG	Jun 2, 2026
India	1-Adamantanamine hydrochloride	1 KG	Apr 10, 2026
India	L-Proline	5.00 KG	Apr 7, 2025
India	1-Adamantylamine Hydrochloride	1.00 KG	Jul 20, 2026
India	1-Adamantanamine hydrochloride	2000 KG	May 22, 2026
India	1-adamantanamine hydrochloride	5 MT	May 3, 2024
India	1-aminoadamantane hydrochloride	50 KG	May 26, 2025
India	1-Adamantanamine hydrochloride	500 KG	Aug 12, 2024
India	1-adamantanamine hydrochloride	1 MT	Aug 9, 2024
India	1-adamantanamine hydrochloride	5 MT	May 7, 2024

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Amantadine Hydrochloride 100%

Product Description

Seller Information