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Best Quality 99% USP Pregabalin Raw Material Powder CAS 148553-50-8 with fast delivery

Name: Best Quality 99% USP Pregabalin Raw Material Powder CAS 148553-50-8 with fast delivery
Brand: HyperChem
SKU: pr2410291340
Price: 100 USD
Availability: InStock

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CAS No.:

148553-50-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

SHANGHAI

Brand:

HyperChem

Packaging:

1kg/Bag, 25kg/drum

Sample Available:

Yes

Price valid (until):

2024-11-29

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

10 days

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Details
Seller Information
Inquiry History

Description

Name	Pregabalin
CAS number	148553-50-8
EINECS number	604-639-1
Synonym	(R-)-3-Isobutyl GABA; PD 144723; PD-144723; PD144723; CI 1008; CI-1008; HSDB 7530; Lyrica; Pregabalin; (S)-3-(Aminomethyl)-5-methylhexanoic acid
Description	Pregabalin is a prescription medication primarily used to treat conditions such as epilepsy, neuropathic pain, fibromyalgia, and anxiety. It functions as an anticonvulsant and analgesic by binding to the alpha-2 delta subunit of voltage-gated calcium channels in the central nervous system (CNS), which helps reduce excitatory neurotransmitter release and exerts antinociceptive and anticonvulsant activity.
Structure
Molecular Formula	C8H17NO2
Molecular Weight	159.23 g/mol
Appearance	Solid powder
Quality Standard	USP Standard
Assay	≥98%
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Store in cool place. Keep container tightly closed in a dry and well ventilated place.
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Aluminium Tin, Fiber drum
Origin	China
HS Code	2915900090

Pregabalin More Info

Pregabalin is a non-gamma-aminobutyric acid (GABA) receptor agonist or antagonist, a novel calcium channel modulator that blocks voltage-dependent calcium channels and reduces neurotransmitter release. It is used clinically for neuralgia associated with diabetic peripheral neuropathy, postherpetic neuralgia and adjunctive treatment of partial seizures in adults, generalized anxiety disorder, central neuralgia (including neuralgia accompanying spinal cord injuries, strokes and multiple sclerosis) and fibromyalgia.

Mechanism of Action

Pregabalin does not directly act on GABA receptors or convert to GABA. Instead, it binds to the alpha-2 delta subunit of voltage-gated calcium channels, thereby reducing the release of excitatory neurotransmitters such as glutamate and noradrenaline. This action helps calm overactive nerves and reduce pain signals sent by damaged nerves.

Uses

1. Epilepsy: Pregabalin is used as an adjunctive therapy for partial seizures with or without secondary generalization.
2. Neuropathic Pain: It is effective in treating various types of neuropathic pain, including diabetic peripheral neuropathy, postherpetic neuralgia, and other chronic pain conditions .
3. Fibromyalgia: Pregabalin is the first drug approved in the USA for the treatment of fibromyalgia.
4. Anxiety Disorders: It is also used to treat generalized anxiety disorder.

Dosage and Administration

Pregabalin is available in various forms including oral capsules, solutions, and extended-release tablets. The typical dosage ranges from 150 mg to 600 mg per day, divided into two or three doses. The starting dose is generally 150 mg daily, which can be adjusted based on the patient's response and tolerance

Safety and Side Effects

While pregabalin is generally well-tolerated, it can cause side effects, which may include:
Common Side Effects: Dizziness, drowsiness, weight gain, dry mouth, blurred vision.
Serious Side Effects: Allergic reactions (such as hives or difficulty breathing), mood changes (including depression or suicidal thoughts), and breathing difficulties.
Withdrawal Symptoms: Abrupt discontinuation can lead to insomnia, nausea, headache, anxiety, and irritability

Precautions

Patients should inform their healthcare provider about any history of:
Mood disorders or suicidal thoughts
Heart problems
Kidney disease
Substance abuse

Package Image

FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
LC at sight
DP at sight

Bank transfer

PayPal

Bitcoin...

Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express
FedEx UPS DHL EMS
Fast: 3-7 days around, high cost, door to door service

By Air
Suitable for more than 50kg
Fast: 3-7 days, hight cost, port to port, professional broker needed

By Sea
Suitable for more than 500kg
Fast: 7-45 days, low cost, port to port, professional broker needed

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders:
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.

ECHEMI Editorial Reference

Off-White SolidPregabalin is a second- generation antiepileptic drug (AED) known with the proprietary brand name of Lyrica (Pfizer, Tadworth) in the UK and USA (Pfizer, New York, NY). As a follow-up to its g-aminobutyric acid (GABA) agonist gabapentin, Pfizer hasdeveloped and launched pregabalin for the treatment of epilepsy and neuropathicpain. Although pregabalin is a structural analog of GABA, it does not interact withGABA-A or GABA-B receptors or influence GABA uptake. The exact mec
Solid
Pregabalin is a gamma-amino acid that is gamma-aminobutyric acid (GABA) carrying an isobutyl substitutent at the beta-position (the S-enantiomer). Binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues. It has a role as an anticonvulsant and a calcium channel blocker. It derives from a gamma-aminobutyric acid.|Pregabalin is a DEA Schedule V controlled substance. Substances in the DEA Schedule V have a low potential for abuse relative to substances listed in Schedule IV and consist primarily of preparations containing limited quantities of certain narcotics.|Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively defined, there is evidence that pregabalin exerts its effects by binding to the α2δ subunit of voltage-dependent calcium channels. Pregabalin is marketed by Pfizer under the trade name Lyrica and Lyrica Cr (extended release). It may have dependence liability if misused but the risk appears to be highest in patients with current or past substance use disorders.|Pregabalin is an inhibitor of neuronal activity used for therapy of painful neuropathy and as an anticonvulsant. Therapy with pregabalin is not associated with serum aminotransferase elevations, and clinically apparent liver injury from pregabalin has been reported but appears to be quite rare.|Pregabalin is a 3-isobutyl derivative of gamma-amino butyric acid (GABA) with anti-convulsant, anti-epileptic, anxiolytic, and analgesic activities. Although the exact mechanism of action is unknown, pregabalin selectively binds to alpha2delta (A2D) subunits of presynaptic voltage-dependent calcium channels (VDCCs) located in the central nervous system (CNS). Binding of pregabalin to VDCC A2D subunits prevents calcium influx and the subsequent calcium-dependent release of various neurotransmitters, including glutamate, norepinephrine, serotonin, dopamine, and substance P, from the presynaptic nerve terminals of hyperexcited neurons; synaptic transmission is inhibited and neuronal excitability is diminished. Pregabalin does not bind directly to GABA-A or GABA-B receptors and does not alter GABA uptake or degradation.|A gamma-aminobutyric acid (GABA) derivative that functions as a CALCIUM CHANNEL BLOCKER and is used as an ANTICONVULSANT as well as an ANTI-ANXIETY AGENT. It is also used as an ANALGESIC in the treatment of NEUROPATHIC PAIN and FIBROMYALGIA.

Certificates

Basic Info

Product Name:

Pregabalin

Other Name:

Hexanoic acid,3-(aminomethyl)-5-methyl-,(3S)-;Hexanoic acid,3-(aminomethyl)-5-methyl-,(S)-;(3S)-3-(Aminomethyl)-5-methylhexanoic acid;PD 144723;CI 1008;Pregabalin;Lyrica;(S)-Pregabalin;(S)-(+)-3-(Aminomethyl)-5-methylhexanoic acid;(2S)-3-(Aminomethyl)-5-methylhexanoic acid;Gabanext 75;Pregalin 75;Neugaba 75;Maxgalin 75;Mahagaba-75;(S)-3-(Aminomethyl)-5-methylhexanoic acid

CAS No.:

148553-50-8

Molecular Formula:

C8H17NO2

InChIKeys:

InChIKey=AYXYPKUFHZROOJ-ZETCQYMHSA-N

Molecular Weight:

159.22600

Exact Mass:

159.23

EC Number:

604-639-1

UNII:

55JG375S6M

DEA Code Number:

2782

DSSTox ID:

DTXSID1045950

NCI Thesaurus Code:

C64625

Color/Form:

White to off-white crystalline solid

ATC Code:

N03AX16|QN03AX16|N - Nervous system

HScode:

2915900090

Categories:

Anxiolytics

Characteristics

PSA:

63.32000

XLogP3:

1.78240

Appearance:

Solid

Density:

0.997 g/cm3

Melting Point:

195 °C (decomp) @ Solvent: Isopropanol

Boiling Point:

274ºC at 760 mmHg

Flash Point:

119.5ºC

Refractive Index:

1.464

Water Solubility:

deionized water: ≥10mg/mL

Storage Conditions:

Store at 25 deg C (77 deg F); excursions permitted to 15 to 30 deg C (59 to 86 deg F).

Vapor Pressure:

0.00153mmHg at 25°C

Specific rotation:

Specific optical rotation = +10.52 deg/D (c = 1.00 in water)

Henrys Law Constant:

Henry's Law constant = 6.89X10-11 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

pKa1 = 4.2; pKa2 = 10.6

Experimental Properties:

The log of the partition coefficient (n-octanol/0.05M phosphate buffer) at pH 7.4 is -1.35|Hydroxyl radical reaction rate constant = 4.1X10-11 cu cm/molec-sec at 25 °C (est)

See More Pregabalin Properties 

Hazard Identification

Classification of the substance or mixture

Serious eye damage, Category 1

Reproductive toxicity, Category 2

Specific target organ toxicity â repeated exposure, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H318 Causes serious eye damage H361 Suspected of damaging fertility or the unborn child H373 May cause damage to organs through prolonged or repeated exposure
Prevention	P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P203 Obtain, read and follow all safety instructions before use. P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Response	P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help. P318 IF exposed or concerned, get medical advice. P319 Get medical help if you feel unwell.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Pregabalin Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Company Certificates
- Certification Report by Bureau Veritas
About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

279 Inquiries

Country	Product	Purchase Quantity	Date Posted
Kampuchea (Cambodia )	Pregabalin	2 KG	Oct 29, 2026
Sweden	Pregabalin	1 KG	Oct 19, 2026
Germany	Pregabalin	100 G	Oct 16, 2026
Canada	Pregabalin	1 KG	Oct 14, 2026
Germany	Pregabalin	20 G	Oct 13, 2026
Germany	Pregabalin pulver	1 KG	Oct 6, 2026
United States	Pregabalin	100 G	Oct 3, 2026
United Kingdom	Pregabalin	10 G	Oct 2, 2026
Germany	Pregabalin	25 KG	Sep 29, 2026
Sweden	Pregabalin	1 KG	Sep 25, 2026
Kazakstan	Pregabalin	25 KG	Sep 16, 2026
United States	Pregabalin	10 PCS	Sep 14, 2026
China	Pregabalin	2 KG	Sep 12, 2026
United States	Pregabalin	1 MT	Sep 12, 2026
China	Pregabalin	2 KG	Sep 11, 2026
Saudi Arabia	Pregabalin 99% White Crystalline Powder 148553-50-8 From Biocar Pregabalin 99% White Crystalline Pow	200 G	Sep 4, 2026
United States	Pregabalin	1 KG	Sep 4, 2026
Sweden	Pregabalin	1 KG	Sep 3, 2026
Saudi Arabia	Pregabalin	500 G	Sep 2, 2026
Malta	Pregabalin	25 MT	Aug 30, 2026

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Best Quality 99% USP Pregabalin Raw Material Powder CAS 148553-50-8 with fast delivery

Product Details

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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