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Agomelatine-ECHEMI

2 Inquiries

Unit Price: Get Latest Price
CAS No.:

138112-76-2

Grade:

Pharmaceutical Grade

Port:

Any China Port

Packaging:

1kgs/ bag

Price valid (until):

2024-12-01

Company Type:
Distributor
Location:
China
Qualification:
Main Products:

API,Intermediate

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Agomelatine is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. Agomelatine was developed in Europe by Servier Laboratories Ltd. and submitted to the European Medicines Agency (EMA) in 2005. The Committee for Medical Products for Human Use (CHMP) recommended refusal of marketing authorization on 27 July 2006. The major concern was that efficacy had not been sufficiently shown. In 2006 Servier sold the rights to develop Agomelatine in the US to Novartis.

    The development for the US market was discontinued in October 2011. It is currently sold in Australia under the Valdoxan trade name.

    Items Specifications
    Type Small Molecule
    Groups Approved, Investigational
    Weight Average: 243.301
    Monoisotopic: 243.125928793
    Chemical Formula C15H17NO2
    Indication Agomelatine is indicated to treat major depressive episodes in adults.

    Basic Info
    Product Name:

    Agomelatine

    Other Name:

    Acetamide,N-[2-(7-methoxy-1-naphthalenyl)ethyl]-;N-[2-(7-Methoxy-1-naphthalenyl)ethyl]acetamide;S 20098;N-[2-(7-Methoxy-1-naphthyl)ethyl]acetamide;Agomelatine;Valdoxan;N-[2-(7-Methoxynaphthalen-1-yl)ethyl]acetamide;AGO 178;Thymanax

    CAS No.:

    138112-76-2

    Molecular Formula:

    C15H17NO2

    InChIKeys:

    InChIKey=YJYPHIXNFHFHND-UHFFFAOYSA-N

    Molecular Weight:

    243.30100

    Exact Mass:

    243.30

    UNII:

    137R1N49AD

    DSSTox ID:

    DTXSID3057642

    ATC Code:

    N06AX22|N - Nervous system

    HScode:

    2924199090

    Categories:

    Other Chemical Drugs

    Characteristics
    PSA:

    38.33000

    XLogP3:

    2.7

    Appearance:

    white solid

    Density:

    1.109g/cm3

    Melting Point:

    109-110 °C @ Solvent: Toluene, Hexane

    Boiling Point:

    478.8ºC at 760 mmHg

    Flash Point:

    243.4ºC

    Refractive Index:

    1.582

    Water Solubility:

    7.76e-03 g/L

    Collision Cross Section:

    156.3 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]

    Hazard Identification

    Classification of the substance or mixture

    Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H400 Very toxic to aquatic life

    Precautionary statement(s)
    Prevention

    P273 Avoid release to the environment.

    Response

    P391 Collect spillage.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    API,Intermediate

    Payment Terms:

    TT against copy of documents,L/C

    Average lead Time:

    30

    Total Annual Revenue:

    Above $100 million

    Total Employees:

    201-300

    About Echemi Pharmaceutical 

    Echemi’s philosophy is to seek for higher quality, to explore frontier area. The progress of human society, the extension of life expectancy, and the conquest of disease are all derived from the numerous businesses and individuals who have quietly dedicated themselves in the pharmaceutical industry. It’s the controlling of supply chain quality that ensures the efficacy. It’s the continuous exploration that promotes the development of the pharmaceutical industry and benefits more future generations. The pursuit of high quality requires all partners of Echemi Pharmaceutical to be screened, whether its certificate, qualification or scale. In the field of renewal, we will embrace all new changes and make more contributions to the development of pharmaceutical industry.

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    Advantage for Pharmaceutical 

    • Having been working in pharmaceutical field for more then 15 years, we have experienced regulatory team, quality control team, sourcing team, technical support team, and logistics team. And we are familiar with the regulatory requirements from different areas, can offer tailored service for our customers.

    • We have hundreds of strategic partners for APIs, intermediates, and custom synthesis. All of our partners are ready to support our customers with documents, and be audited.

    • We can offer custom synthesis for some new chemical structures and some materials which there are no reliable suppliers.

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    Product Category 

    We care for human and animal health and we are committed to creating a better social environment.

    •  Human API

    • Intermediate

    • Veterinary API

    • Agrochemical

    • Fine Chemical

    • Custom Synthesis



  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Agomelatine

    30 G Apr 28, 2026
    Sweden

    Agomelatine

    25 G Feb 4, 2024
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