Flammable liquids, Category 2

Skin corrosion, Sub-category 1B

no data available

If inhaled

Following skin contact

Following eye contact

Following ingestion

Vapor irritates mucous membranes. Ingestion of liquid or contact with eyes or skin causes severe irritation. (USCG, 1999)

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist respirations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary . Monitor for shock and treat if necessary . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Activated charcoal is not effective . Do not attempt to neutralize because of exothermic reaction. Cover skin burns with dry, sterile dressings after decontamination . Organic acids and related compounds

Evacuate surrounding area.

Special Hazards of Combustion Products: When heated to decomposition, hydrogen chloride and phosgene, extremely poisonous gases, are evolved. Behavior in Fire: Vapor is heavier than air and may travel a considerable distance to a source of ignition and flash back. (USCG, 1999)

Use powder, carbon dioxide. NO hydrous agents, water. In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water.

Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Do NOT wash away into sewer. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT wash away into sewer. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

Cover any spills with sufficient amt of sodium bicarbonate. Remove the mixture in a container such as a fiber drum, plastic bag or carton box for easy disposal in an incinerator, and dispose by burning in a furnace. Wash the spilled spot thoroughly with water.

NO open flames, NO sparks and NO smoking. NO contact with hot surfaces. Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent build-up of electrostatic charges (e.g., by grounding). Do NOT use compressed air for filling, discharging, or handling. Use non-sparking handtools. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Fireproof. Separated from incompatible materials. See Chemical Dangers. Dry. Well closed.Separate from alcohols, alkalies, amines, and strong oxidizing materials. Store in a cool, dry well-ventilated location. Outside or detached storage is preferred. Inside storage should be in a standard flammable liquids storage warehouse, room, or cabinet.

Occupational Exposure limit values

Biological limit values

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

Eye/face protection

Skin protection

Respiratory protection

Thermal hazards

Decomposes on heating and on burning. This produces toxic and corrosive fumes including hydrogen chloride (see ICSC 0163) and phosgene (see ICSC 0007). Reacts violently with water, alcohols, acids, bases, certain powdered metals and many other compounds. This generates fire and explosion hazard. Attacks many metals in the presence of water. Products of hydrolysis in water include corrosive hydrochloric acid and acetic acid.

Readily hydrolyzes to form hydrogen chloride & acetic acid

DANGEROUS, WHEN EXPOSED TO HEAT OR FLAME. ...The vapour is heavier than air and may travel along the ground; distant ignition possible.ACETYL CHLORIDE reacts violently with water, steam, methanol or ethanol to form hydrogen chloride and acetic acid. Reacts vigorously with bases, both organic and inorganic. Incompatible with oxidizing agents and alcohols. Produces highly toxic fumes of phosgene gas and chlorine when heated to decomposition [Sax, 9th ed., 1996, p. 35]. Reaction in a confined space with even a small amount of water may cause a violent eruption of gases [Bretherick, 5th ed., 1995, p. 281]. Vapor forms an explosive mixture with air [Kirk-Othmer, 3rd ed., Vol. 1, 1978, p. 162]. Polymerization reaction with dimethyl sulfoxide is particularly violent [Buckley, A., J. Chem. Ed., 1965, 42, p. 674]. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

no data available

Water reactive. Violent exothermic decomposition with water produces corrosive hydrochloric and acetic acids. Reacts violently with alcohols, alkalies, amines, and strong oxidizing materials.

May decompose during preparation. ... when heated to decomposition, emits highly toxic fumes of phosgene and hydrogen chloride (cl-).

Acute toxicity

• Oral: LD50 - rat - 910 mg/kg bw.
• Inhalation: no data available
• Dermal: no data available

Skin corrosion/irritation

Serious eye damage/irritation

Respiratory or skin sensitization

Germ cell mutagenicity

Carcinogenicity

Reproductive toxicity

STOT-single exposure

STOT-repeated exposure

Aspiration hazard

• Toxicity to fish: LC50 - Pimephales promelas - 42 mg/L - 96 h.
• Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 65 mg/L - 48 h.
• Toxicity to algae: EC50 - Navicula seminulum - 73.4 mg/L - 96 h.
• Toxicity to microorganisms: no data available

no data available

Acetyl chloride will decompose violently in water(1) forming acetic acid and hydrochloric acid(2). Because of its short half-life in water, bioconcentration of acetyl chloride in aquatic organisms is very unlikely(SRC).

Using a structure estimation method based on molecular connectivity indices(1), the Koc for acetyl chloride can be estimated to be 2(SRC). According to a classification scheme(2), this estimated Koc value suggests that acetyl chloride is expected to have very high mobility in soil. However, in view of its violent decomposition in the presence of water(3) and the high reactivity of this compound towards molecules with active hydrogen groups such as natural products containing amine, phenol, and alcohol functional groups that occur in soil(4), it is unlikely that acetyl chloride would persist for long in moist soils(SRC).

no data available

Product

Contaminated packaging

no data available

no data available

Information on revision

Abbreviations and acronyms

• CAS: Chemical Abstracts Service
• ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
• RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
• IMDG: International Maritime Dangerous Goods
• IATA: International Air Transportation Association
• TWA: Time Weighted Average
• STEL: Short term exposure limit
• LC50: Lethal Concentration 50%
• LD50: Lethal Dose 50%
• EC50: Effective Concentration 50%