Benazepril CAS 86541-75-5
1 Inquiries
86541-75-5
Pharmaceutical Grade
99%
Shanghai
1kg/bag;25kg/Cardboard Drum
2025-05-31
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceBenazepril, an angiotensin converting enzyme inhibitor, which is a medication used to treat high blood pressure.Target: angiotensin converting enzyme (ACE)Benazepril is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure. Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor [1].Animals were randomly divided into
Solid
Benazepril is a benzazepine that is benazeprilat in which the carboxy group of the 2-amino-4-phenylbutanoic acid moiety has been converted to the corresponding ethyl ester. It is used (generally as its hydrochloride salt) as a prodrug for the angiotensin-converting enzyme inhibitor benazeprilat in the treatment of hypertension and heart failure. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and a prodrug. It is a benzazepine, a dicarboxylic acid monoester, an ethyl ester and a lactam. It derives from a benazeprilat. It is a conjugate base of a benazepril(1+).|Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure. Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor.|Benazepril is an Angiotensin Converting Enzyme Inhibitor. The mechanism of action of benazepril is as an Angiotensin-converting Enzyme Inhibitor. The physiologic effect of benazepril is by means of Decreased Blood Pressure.|Benazepril is an angiotensin-converting enzyme (ACE) inhibitor widely used in the therapy of hypertension. Benazepril is associated with a low rate of transient serum aminotransferase elevations and has been linked to rare instances of acute liver injury.|Benazepril is a carboxyl-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, benazepril is metabolized to its active form benazeprilat. Benazeprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II resulting in vasodilation. Benazeprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.Basic Info-
Product Name:
Benazepril
Other Name:1H-1-Benzazepine-1-acetic acid,3-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-,(3S)-;1H-1-Benzazepine-1-acetic acid,3-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-,[S-(R*,R*)]-;(3S)-3-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid;Benazepril;Cibacen WS;Benapril;Cibacen;Briem;Cibacene;116764-54-6
CAS No.:86541-75-5
Molecular Formula:C24H28N2O5
InChIKeys:InChIKey=XPCFTKFZXHTYIP-PMACEKPBSA-N
Molecular Weight:424.49
Exact Mass:424.49
UNII:UDM7Q7QWP8
DSSTox ID:DTXSID5022645
NCI Thesaurus Code:C61645
ATC Code:C09AA07|C - Cardiovascular system
Categories:
Characteristics-
PSA:
95.9
XLogP3:1.3
Appearance:Solid
Density:1.3±0.1 g/cm3
Melting Point:148.5 °C
Boiling Point:691.2°C at 760 mmHg
Flash Point:371.8±31.5 °C
Refractive Index:1.608
Water Solubility:1.05e-02 g/L
Storage Conditions:Store in original container in a cool dark place.
Vapor Pressure:6.40X10-13 mm Hg at 25 °C (est)
Specific rotation:D -159° (c = 1.2 in ethanol)
Henrys Law Constant:Henry's Law constant = 4.90X10-16 atm-cu m/mol at 25 °C (est)
Experimental Properties:Crystals from 3-pentanone + methanol (10:1). MW: 490.96. MP: 188-190 °C. Specific optical rotation: -141.0 deg at 25 °C/D (c = 0.9 in ethanol). Soluble in water, ethanol, methanol|Mol wt 396.44. MP: 270-272 °C. Specific optical rotation: -200.5 deg at 25 °C/D (c = 1 in 3 percent aqueous NH4OH) /Benazepril diacid/
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10
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Location:
XINYUAN DADUHUI PHASE 1, NO.258 TAOYUAN NORTH ROAD, LIANHU DISTRICT, XI 'AN , SHAANXI CHINA
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Payment Terms:
TT against copy of documents,100% TT in advance
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Average lead Time:
30
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2023
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
India
benazepril
25 KG Jun 16, 2026 Post an enquiry for this product
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