Vortioxetine 98% purity with best price cas 508233-74-7 and Vortioxetine raw material
508233-74-7
Pharmaceutical Grade
99%
shanghai
1kg/bag;25kg/Cardboard Drum
Yes
2024-12-14
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceVortioxetine is a inhibitor of 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT, with Ki values of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.
Vortioxetine is an N-arylpiperazine in which the aryl group is specified as 2-[(2,4-dimethylphenyl)sulfanyl]phenyl. Used (as its hydrobromide salt) for treatment of major depressive disorder. It has a role as an antidepressant, an anxiolytic drug, a serotonergic agonist and a serotonergic antagonist. It is a N-arylpiperazine and an aryl sulfide. It is a conjugate base of a vortioxetine(1+).|Vortioxetine is an atypical antipsychotic and antidepressant indicated for the treatment of major depressive disorder (MDD). It is classified as a serotonin modulator and simulator (SMS) as it has a multimodal mechanism of action towards the serotonin neurotransmitter system whereby it simultaneously modulates one or more serotonin receptors and inhibits the reuptake of serotonin. More specifically, vortioxetine acts via the following biological mechanisms: as a serotonin reuptake inhibitor (SRI) through inhibition of the serotonin transporter, as a partial agonist of the 5-HT1B receptor, an agonist of 5-HT1A, and an antagonist of the 5-HT3, 5-HT1D, and 5-HT7 receptors. SMSs were developed because there are many different subtypes of serotonin receptors, however, not all of these receptors appear to be involved in the antidepressant effects of SRIs. Some serotonin receptors seem to play a relatively neutral or insignificant role in the regulation of mood, but others, such as 5-HT1A autoreceptors and 5-HT7 receptors, appear to play an oppositional role in the efficacy of SRIs in treating depression.|Vortioxetine is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum aminotransferase elevations during treatment, but has not been linked to instances of clinically apparent acute liver injury.|A piperazine derivative that acts as a serotonin reuptake inhibitor, as a 5-HT3 receptor antagonist, and 5-HT1A receptor agonist. It is used for the treatment of anxiety and depression.Basic Info-
Product Name:
Vortioxetine
Other Name:Piperazine,1-[2-[(2,4-dimethylphenyl)thio]phenyl]-;1-[2-[(2,4-Dimethylphenyl)thio]phenyl]piperazine;Vortioxetine;Lu AA 21004;1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine;Brintellix;Trintellix
CAS No.:508233-74-7
Molecular Formula:C18H22N2S
InChIKeys:InChIKey=YQNWZWMKLDQSAC-UHFFFAOYSA-N
Molecular Weight:298.44568
Exact Mass:298.45
EC Number:1308068-626-2
UNII:3O2K1S3WQV
ATC Code:N06AX26|N - Nervous system
HScode:2933599090
Categories:
Characteristics-
PSA:
40.6
XLogP3:4.2
Density:1.16
Flash Point:210.7±28.7 °C
Refractive Index:1.643
Water Solubility:In water, 7.8 mg/L at 25 deg C (est)
Storage Conditions:Store at 77 deg F (25 deg C); excursions permitted to 59 deg F to 86 deg F (15 deg C to 30 deg C).
Vapor Pressure:5.43X10-8 mm Hg at 25 deg C (est)
Henrys Law Constant:Henry's Law constant = 8.03X10-11 atm-cu m/mol at 25 °C (est)
Dissociation Constants:pKa = 8.84 (secondary amine) (est)
Experimental Properties:White to very slightly beige powder; slightly soluble in water /Vortioxetine hydrogen bromide/|Hydroxyl radical reaction rate constant = 2.14X10-11 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Reproductive toxicity, Category 2
Specific target organ toxicity â single exposure, Category 2
Specific target organ toxicity â repeated exposure, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H361 Suspected of damaging fertility or the unborn child
H371 May cause damage to organs
H373 May cause damage to organs through prolonged or repeated exposure
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P318 IF exposed or concerned, get medical advice.
P308+P316 IF exposed or concerned: Get emergency medical help immediately.
P319 Get medical help if you feel unwell.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10
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Location:
XINYUAN DADUHUI PHASE 1, NO.258 TAOYUAN NORTH ROAD, LIANHU DISTRICT, XI 'AN , SHAANXI CHINA
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Payment Terms:
TT against copy of documents,100% TT in advance
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Average lead Time:
30 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2023
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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