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Benzhexol Hydrochloride,

3 Inquiries

Unit Price:

$1000/KG FOB

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CAS No.:

52-49-3

Grade:

Pharmaceutical Grade

Content:

99.9%

Port:

SHANGHAI PORT

Packaging:

25kg/Drum

Sample Available:

Yes

Price valid (until):

2028-11-30

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Shaanxi Dideu Medichem Co. Ltd

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

7 days

Qualification:

Main Products:

Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

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Product Description
Seller Information
Inquiry History

Description

Chlorpheniramine hydrochloride is a central anticholinergic and anti Parkinson's disease drug that selectively blocks the cholinergic neural pathway in the striatum, with less peripheral effect. This is beneficial for restoring the balance of dopamine and acetylcholine in the brains of Parkinson's disease patients and improving their Parkinson's disease symptoms. Used for Parkinson's disease and Parkinson's syndrome. It can also be used for drug-induced extrapyramidal disorders. Its pharmacological effects and side effects are similar in nature to those of belladonna alkaloids.Chlorpheniramine hydrochloride is a central anticholinergic and anti Parkinson's disease drug that selectively blocks the cholinergic neural pathway in the striatum, with less peripheral effect. This is beneficial for restoring the balance of dopamine and acetylcholine in the brains of Parkinson's disease patients and improving their Parkinson's disease symptoms. Used for Parkinson's disease and Parkinson's syndrome. It can also be used for drug-induced extrapyramidal disorders. Its pharmacological effects and side effects are similar in nature to those of belladonna alkaloids.Chlorpheniramine hydrochloride is a central anticholinergic and anti Parkinson's disease drug that selectively blocks the cholinergic neural pathway in the striatum, with less peripheral effect. This is beneficial for restoring the balance of dopamine and acetylcholine in the brains of Parkinson's disease patients and improving their Parkinson's disease symptoms. Used for Parkinson's disease and Parkinson's syndrome. It can also be used for drug-induced extrapyramidal disorders. Its pharmacological effects and side effects are similar in nature to those of belladonna alkaloids.Chlorpheniramine hydrochloride is a central anticholinergic and anti Parkinson's disease drug that selectively blocks the cholinergic neural pathway in the striatum, with less peripheral effect. This is beneficial for restoring the balance of dopamine and acetylcholine in the brains of Parkinson's disease patients and improving their Parkinson's disease symptoms. Used for Parkinson's disease and Parkinson's syndrome. It can also be used for drug-induced extrapyramidal disorders. Its pharmacological effects and side effects are similar in nature to those of belladonna alkaloids.

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Items	Specifications

ECHEMI Editorial Reference

Trihexyphenidyl hydrochloride is an antiparkinsonian agent of the antimuscarinic class, binds to the M1 muscarinic receptor.
Trihexyphenidyl hydrochloride is an aralkylamine.|One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders and as an antispasmodic.
Trihexyphenidyl is an antagonist of M1muscarinic acetylcholine receptors. It binds to rat M1receptors in cerebral cortex selectively over rat M2receptors in heart tissue (IC50s = 3.7 and 31 nM, respectively). Trihexyphenidyl inhibits contractions induced by acetylcholine in guinea pig ileum (IC50= 22 nM). It also inhibits oxotremorine-induced tremors and physostigmine-induced mortality in mice (ED50s = 2 and 3.6 mg/kg, respectively). Trihexyphenidyl (20 mg/kg) improves abnormal movement in a mouse model of L-3,4-dihydroxyphenylalanine (L-DOPA) responsive dystonia (DRD) that expresses mutant tyrosine hydroxylase (TH). Formulations containing trihexyphenidyl have been used in the symptomatic treatment of Parkinson''s disease.
Benzhexol hydrochloride is White Solid
ChEBI: Trihexyphenidyl hydrochloride is an aralkylamine.

Basic Info

Product Name:

Benzhexol hydrochloride

Other Name:

TRIHEXYLPHENIDYL HYDROCHLORIDE;1-phenyl-1-cyclohexyl-3-piperidyl-1-propanolhydrochloride;3-(1-piperidyl)-1-cyclohexyl-1-phenyl-1-propanolhydrochloride;alpha-cyclohexyl-alpha-phenyl-1-piperidinepropanohydrochloride;artanehydrochloride;benzhexolchloride;cyclodol;pacitane

CAS No.:

52-49-3

Molecular Formula:

C20H31NO.ClH

InChIKeys:

QDWJJTJNXAKQKD-UHFFFAOYSA-N

Molecular Weight:

337.93

Exact Mass:

337.217255

EC Number:

200-142-5

NSC Number:

757357

DSSTox ID:

DTXSID8045802

Color/Form:

white

HScode:

2933399090

Categories:

Antibiotics

Characteristics

PSA:

23.47000

XLogP3:

5.07040

Appearance:

white solid

Density:

0.9801 (rough estimate)

Melting Point:

Free base, mp 114.3-115.0°

Boiling Point:

447.9ºC at 760mmHg

Flash Point:

211ºC

Refractive Index:

1.5790 (estimate)

Water Solubility:

670.9ug/L(22.5 ºC)

Toxicity:

TDLo orl-wmn: 800 mg/kg:BAH BJPYAJ 145,300,84

Flammability characteristics:

Combustion produces toxic nitrogen oxides and hydrogen chloride fumes; drug side effects: misinterpretation, hallucinations, eye diseases, confusion

Collision Cross Section:

174.9 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Critical Temperature & Pressure:

Inert atmosphere,Room Temperature

See More Benzhexol hydrochloride Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Benzhexol hydrochloride Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

Location:
https://www.dideu.com/en/

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7 days

Total Annual Revenue:
Above $100 million

Total Employees:
Above 1000

Year of Establishment:
2016

Company Certificates
- ISO Certificate
- REACH
Company Profile
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Inquiry History

3 Inquiries

Country	Product	Purchase Quantity	Date Posted
Indonesia	Benzhexol Hydrochloride	20 KG	Nov 19, 2024
Indonesia	Benzhexol HCl	100 MT	Oct 30, 2024
Sri Lanka	Benzhexol Hydrochloride BP 2024 / BP 2025	100 KG	Jun 13, 2026

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Benzhexol Hydrochloride,

Product Description

Seller Information