Gabapentein manufacturer supply high purity Gabapentin 99% White Powder

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• Product Feature:
  

• Gabapentin is a GABA analogue used to treat epilepsy and neuropathic pain. It is used as an additional treatment for patients with localized seizures that cannot be satisfactorily controlled or tolerated by conventional anti-epileptic drugs, and for patients with localized seizures that subsequently become generalized. Antianxiety drug.

  Gabapentin is used with other medications to prevent and control seizures. It is also used to relieve nerve pain following shingles (a painful rash due to herpes zoster infection) in adults.

  Gabapentin is a prescription medication primarily used to treat seizures and nerve pain. It is also used for conditions like restless leg syndrome and postherpetic neuralgia. The drug works by binding to voltage-gated calcium channels, which helps reduce the release of excitatory neurotransmitters, thus calming overactive nerves in the body

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    Mechanism of Action

    Gabapentin is structurally similar to the neurotransmitter gamma-aminobutyric acid (GABA) but does not bind to GABA receptors. Instead, it primarily works by:
    Binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This action inhibits excitatory neurotransmitter release, which helps reduce neuronal excitability and pain transmission.
    Modulating neurotransmitter release, particularly glutamate, which is involved in pain pathways.

    Applications

    Gabapentin is indicated for several conditions, including:
    Neuropathic Pain: Effective for conditions such as diabetic neuropathy and postherpetic neuralgia.
    Seizure Disorders: Approved as an adjunctive therapy for partial seizures in adults and children.
    Restless Legs Syndrome: Sometimes used off-label for this condition.
    Anxiety Disorders: Occasionally prescribed off-label for anxiety management.

    Routes of Administration

    Gabapentin can be administered through various routes:
    Oral: Available in capsules, tablets, and oral solution forms.
    Intravenous (IV): Less common but used in specific clinical settings.

    Safety and Side Effects

    Gabapentin is generally well-tolerated, but it can cause various side effects, including:
    Common Side Effects:
    Dizziness
    Fatigue
    Drowsiness
    Peripheral edema (swelling of extremities)
    Serious Side Effects:
    Allergic reactions (e.g., rash, itching)
    Mood changes (e.g., depression, anxiety)
    Suicidal thoughts or behavior
    Monitoring for these effects is essential, especially during the initial treatment phase or when dosage adjustments occur.

    Pharmacokinetics

    The pharmacokinetics of gabapentin include:
    Absorption: Gabapentin is absorbed through the gastrointestinal tract. Its bioavailability decreases with increasing doses due to saturation of transport mechanisms.
    Distribution: It has a volume of distribution of approximately 57-70 L. Gabapentin does not bind significantly to plasma proteins.
    Metabolism: Gabapentin undergoes minimal hepatic metabolism; it is mainly excreted unchanged in urine.
    Half-Life: The elimination half-life ranges from 5 to 7 hours in healthy individuals but may be prolonged in those with renal impairment.

    
    

    
    

    Items	Specifications
    CAS	60142-96-3
    MF	C9H17NO2
    MW	171.24
    Melting Point	162°C
    EINECS	262-076-3
    Storage	Store in cool dry environment, away from direct sunlight

    
    
    
    
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Q1: What's your MOQ?
A:It depends on different products,we can accept sample order or provide free sample for your test.

Q2:How about delivery leadtime?
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

Q3: Is there a discount?
A:Different quantity has different discount.

Q4:How to start orders or make payments?
A:Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T.

Q5: How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

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A: You are always warm welcomed to visit us at any time. Commitment is the No.1 Point of our Enterprise's Value.

Q7.Do you test all your goods before delivery?
A:Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.