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CAS No.:

497-76-7

Grade:

Cosmetics Grade

Content:

99%

Port:

Tianjin

Brand:

Packaging:

25kg/Drum

Price valid (until):

2025-04-30

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Hebei Shunxing Import and Export Co.,Ltd

Company Type:

Trader

Location:

China

Qualification:

Main Products:

HPMC,Lithium Carbonate,Cellulose Acetate Tow,EVA resin,Terpene Resin,PP fiber

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Product Description
Seller Information
Inquiry History

Description

Product Parameters

Product Description

Cosmetic grade Arbutin with cas 497-76-7 from china Arbutin powder

Product Description

Product Name	Arbutin
CAS Number	497-76-7
Molecular Formula	C12H16O7
Molecular weight	272.25
Purity	99%
Appearance	White powder
Melting Point	195-198 °C
Boiling Point	375.31°C (rough estimate)
Density	1.3582 (rough estimate)
Storage	Keep in dark place,Inert atmosphere,Room temperature

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Arbutin CAS 497-76-7 have bulk in stock , delivery fast /high quality /good feedback

Cas 497-76-7 Arbutin Specification

Product name	Arbutin CAS 497-76-7	Manufacture Date	20240.2.10
Batch No.	20240210	Inspection Date	2024.02.10
Quantity	500kg	Report No.	20240210-08
Item	Standard		Result
Quality controlling standard & inspection result
Description	powder		Conforms
Assay	>98%		99%

Conclusion	Pass

Description

Arbutin is also known as arbutin, arbutin, arbutin, arbutin or myricitin. Because it is originally derived from natural green plants, it is a combination of "green", "safe" and "efficient" concepts. Active substance for skin whitening. Arbutin is an ideal whitening agent for whitening cosmetics. There are two optical isomers, namely α and ß, and the bioactive one is the ß isomer. It is white and slightly yellowish powder at room temperature. It is easily soluble in water, methenol, eth-anol and Chemicalbook propyline glycol and glycerin aqueous solution. There is no precipitation after dissolution, and it is insoluble in chlorofo rm, ether, petroleume-ther, etc. It is added in many whitening skin care products. It is named after being found in the leaves of the bearberry of the Rhododendron family, and later in the Rhododendron family Vaccinium bilberry, Rosaceae pear (Western pear, Koyama pear), Saxifraga It is found in the leaves of plants such as Saxifraga in the family Saxifraga, and is used as an additive in medicines and cosmetics after extraction.

Arbutin is currently one of the safest and most effective whitening ingredients popular abroad, and it is also the most competitive skin whitening and spot-removing active agent in the 21st century. In cosmetics, it can effectively whiten and remove freckles on the skin, gradually fade and eliminate skin freckles, chloasma, melanin deposits, acne and age spots. It has high safety, no side effects such as irritation, sensitization, etc. It has good Chemicalbook compatibility with various components of cosmetics, and it is stable in ultraviolet radiation. But arbutin is easy to hydrolyze, so it should be used under the condition of PH value of 5-7. In order to stabilize the performance, an appropriate amount of antioxidants such as sodium bisulfete and vitamin E are usually added to better achieve whitening, freckle removal, moisturizing, softening, wrinkle removal, and anti-inflammatory effects. It can be used to eliminate redness and swelling, promote wound healing without leaving scars, and inhibit the formation of dandruff.

CAS	Purity	Processing	Tyrosinase inhibitory efficacy
Alpha arbutin	84380-01-8	≥99.5%	enzymatically synthesized	around 200times than kojic acid
Beta arbutin	497-76-7	≥99.5%	Chemically Synthesized or extract from bearberry	around 100times than kojic acid

	Recommended Dose	Stability	Safety	Solubility
Alpha arbutin	0.2-2%	Higher	Safer	water soluble
Beta arbutin	1-5%	Lower	inhibit cell growth	water soluble

Product Application

Application

Functions

Cosmetic Function:
(1)Beta arbutin powder protect the skin against damage caused by free radicals
(2)Beta arbutin powder inhibits the formation of melanin pigment by inhibiting Tyrosinase activity,is a kind of skin whitening agent
Medical Function:
(1)Beta arbutin was first used in medical areas as an anti inflammatory and antibacterial agent
(2)Beta arbutin may be used to repress the virulence of bacterial pathogens and to prevent contaminating bacteria, Beta arbutin is also used for treating allergic inflammation of the skin

Applicatrion

1. Cosmetic industry:(Very Good Products for skin brightening)
Alpha-arbutin protect the skin against damage caused by free radicals Alpha Arbutin is a skin whitening agent which is very popular in Japan and Asian countries for skin de-pigmentation, Alpha Arbutin inhibits the formation of melanin pigment by inhibiting Tyrosinase activity. Alpha Arbutin is very safe skin agent for external use which does not have toxicity, stimulation, unpleasant odor or side effect such as Hydroqinone.The encapsulation of Alpha Arbutin constitute a delivery system to potentialize the effect in time. Alpha Arbutin is a way to incorporate the hydrophilic Alpha Arbutin in lipophilic media. Arbutin give three main properties; Whitening effects, anti- age effect and UVB/ UVC filter .
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2. Medical industry:
Back in the 18th century, Alpha-arbutin was first used in medical areas as an anti-inflammatory and antibacterial agent. Alpha Arbutin was used particularly for cystitis, urethritis and pyelitis. These uses still until today where natural medicine uses only natural ingredients to treat any disease. Also Alpha Arbutin may be used to repress the virulence of bacterial pathogens and to prevent contaminating bacteria, Alpha Arbutin is also used for treating allergic inflammation of the skin . More recently, Alpha Arbutin has been used to prevent pigmentation and to whiten the skin beautifully. In the meanwhile, Alpha Arbutin can be used to whiten the skin, to prevent liver spots and freckles, to treat sunburn marks and to regulate melanogenesis.

Packaging & Shipping

The product packaging : 25kg/bag other arrangements can be made upon request

Powder:
            16.5MT/20' FCL Not on Pallets
            13.0MT/20' FCL on Pallets

Granule and Sprinkle:
            20MT/20' FCL Not on Pallets
            16MT/20' FCL on Pallets

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Product Categories

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Packaging & Shipping

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Detailed Photos

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Advantages:
Our Guarantee on quality
1)Purchasing
Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.
2) Inspection
Four steps: sampling, sample pretreatment, measuring and data processing.
3) Producing
a)Each operator must do self-inspection of products and make the corresponding inspection records.
b)Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.
4) Before selling
Test result can be provided before selling.
Third-party detection institution is allowed if you are not satisfied with test results.
4.We provide the professional test data and product information ,eg: COA, HPLC
Superiority
1.Professional synthesis laboratory and manufacture /production base.
2.Strong synthesis team and service team. Professional data management.
3.We provide the professional test data and product information ,eg: MSDS,COA
4..Any inquiries will be replied within 48 hours.
5.All kinds of shipping methods, eg: FedEx,DHL,TNT,BY SEA and BY AIR.
7.Shipping information includes Commercial Invoice,Packing List,COA,BSE/TSE.If your markets have any special requirements, please let us know.
8.We can accept various payment methods,L/C,T/T, etc.
9.Professional packaging can be according the customers' requirement.
10.Product application: Medicinal Chemistry , Biomedicine, Pharmaceutical intermediate, Chemistry experiment ,Biological experiments ,Chemical reagent , for R&D use.

After Sales Service

We guarantee that 100% of your parcel passes through the United States, Britain,Canada, Mexico, France, Germany, Spain, Belgium, Sweden, Poland, and Russia. We have powerful customs clearance agencies in these countries, and our customs clearance company will clear your parcel without any customs issues, sometimes even 1000 kg. Door to door service DDP service. To ensure 100% receipt of your package, if there are any customs issues, we are willing to reissue your package free of charge. Let you have a good experience of our strong shipping capabilities.

We have many customers in those countries and retain long-term cooperation. Provide a large number of high-quality products. They made a lot of money. I am sure we can make more money together. There is money to have glory.

Package and shipment

17.5mt/700carons in 20'' FCL or customized according to your needs.

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Package:

Delivery Time: Around 3-5 workdays after your payment.
Package: In fiber-drums with two-plastic bags inside.
Net Weight: 25kgs/Drum / Gross Weight: 28kgs/Drum
Drum Size & Volume: I.D.42cm × H52cm, 0.08 m³/ Drum
Storage: Stored in dry and cool place, keep away from strong light and heat.
Shelf Life: Two years when properly stored.

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Shipping:

DHL Express, FEDEX and EMS for quantity less than 50KG, usually called as DDU service;
Sea shipping for quantity over 500KG; and air shipping is available for 50KG above;
For high value products, please select air shipping and DHL express for safe;
Please confirm if you can make the clearance when goods reach your customs before placing an order, for buyers from Mexico, Turkey, Italy, Romania,Russia, and other remote area.

Company Profile
Hebei Shunxing Import and Export Co.,Ltd at Shijiazhuang ,covering an area of 10,000M2,is a Chemical high-tech group company with an integrated system of researching,development,production, marketing and sales ability. It mainly produces Inorganic Chemicals, Organic Chemicals, Food and Feed Additives. Our products are widely applied to detergent, water treatment, rubber, plastic, leather, tanning, textiles, paint, oil drilling, food, feeding and pharmaceutical. With ISO9001 quality management system, all our products are manufactured by strict procedures. With the advanced test equipments in our Lab, all shipments are tested carefully before delivery to assure the quality consistency. The quality standard for each customer is established. All the sample and shipment lots have been filed detailed and be able to traced. Through many years of development, our company has become a large-scale enterprise with research, production,assembly and marketing capabilities. Guaranteeing stable and timely supply, credible quality and sincere service, our products sell well in both domestic and overseas markets. Our aim is to provide customers the high quality products, most competitive pricing, the shortest delivery time and the unequaled service. We pursue the management tenet of "Quality is Superior, Service is Supreme, Reputation is First", and will sincerely create and share success with all clients. We welcome you to contact us for more information and look forward to working with you!
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ECHEMI Editorial Reference

Arbutin(β-Arbutin) is a glycoside; a glycosylated hydroquinone extracted from the bearberry plant in the genus Arctostaphylos; inhibits tyrosinase and thus prevents the formation of melanin.IC50 value:Target: tyrosinase
Solid
Hydroquinone O-beta-D-glucopyranoside is a monosaccharide derivative that is hydroquinone attached to a beta-D-glucopyranosyl residue at position 4 via a glycosidic linkage. It has a role as a plant metabolite and an Escherichia coli metabolite. It is a beta-D-glucoside and a monosaccharide derivative. It derives from a hydroquinone.|Extracted from the dried leaves of bearberry plant in the genus Arctostaphylos and other plants commonly in the Ericaceae family, arbutin is a beta-D-glucopyranoside of [DB09526]. It is found in foods, over-the-counter drugs, and herbal dietary supplements. Most commonly, it is an active ingredient in skincare and cosmetic products as a skin-lightening agent for the prevention of melanin formation in various skin conditions that involve cutaneous hyperpigmentation or hyperactive melanocyte function. It has also been used as an anti-infective for the urinary system as well as a diuretic. Arbutin is available in both natural and synthetic forms; it can be synthesized from acetobromglucose and [DB09526]. Arbutin is a competitive inhibitor of tyrosinase (E.C.1.14.18.1) in melanocytes, and the inhibition of melanin synthesis at non-toxic concentrations was observed in vitro. Arbutin was shown to be less cytotoxic to melanocytes in culture compared to [DB09526].

Certificates

Basic Info

Product Name:

Arbutin

Other Name:

β-D-Glucopyranoside,4-hydroxyphenyl;Arbutin;Glucopyranoside,p-hydroxyphenyl,β-D-;4-Hydroxyphenyl β-D-glucopyranoside;Ursin;p-Hydroxyphenyl β-D-glucoside;p-Hydroxyphenyl β-D-glucopyranoside;Hydroquinone β-D-glucopyranoside;Arbutine;Uvasol;β-Arbutin;Hydroquinone glucose;Arbutoside;NSC 4036;Arbutyne;p-Arbutin;30373-96-7;39464-18-1;1779499-53-4

CAS No.:

497-76-7

Molecular Formula:

C12H16O7

InChIKeys:

InChIKey=BJRNKVDFDLYUGJ-RMPHRYRLSA-N

Molecular Weight:

272.25100

Exact Mass:

272.25

EC Number:

207-850-3

UNII:

C5INA23HXF

DSSTox ID:

DTXSID7040152

Color/Form:

Colorless elongated prisms from moist ethyl acetate|White powder (pure synthetic)|Needles (water + 1)

HScode:

29389090

Categories:

Antimicrobials

Characteristics

PSA:

119.61000

XLogP3:

-0.7

Appearance:

white powder

Density:

1.556g/cm3

Melting Point:

199.5 °C

Boiling Point:

561.6ºC at 760 mmHg

Flash Point:

293.4ºC

Refractive Index:

1.65

Water Solubility:

H2O: 10-15 g/100 mL at 20 ºC

Vapor Pressure:

1.9E-13mmHg at 25°C

Specific rotation:

Specific optical rotation: -60.3 deg at 20 °C/D (in water)

Henrys Law Constant:

Henry's Law constant = 1.20X10-19 atm-cu m/mol at 25 °C (est)

Collision Cross Section:

166.6 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|159.52 Å² [M+Na-2H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|164.4 Å² [M+Na]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Experimental Properties:

MP 199 °C after sintering at 163-164 °C ... Also reported as unstable form, mp 165 °C; stable form, mp 199.5-200 °C|Hydroxyl radical reaction rate constant = 9.10X10-11 cu cm/molec-sec at 25 °C (est)

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Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

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Seller Information

Business Type:
Trader

Main Products:
HPMC,Lithium Carbonate,Cellulose Acetate Tow,EVA resin,Terpene Resin,PP fiber

Location:
Building 4, Feicui Building, No. 366 Xinshi North Road, Qiaoxi District, Shijiazhuang City, Hebei Province

Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7

Total Annual Revenue:
$5 million-$10 million

Total Employees:
51-100

Year of Establishment:
2024

Hebei Shunxing Import and Export Co., Ltd. distributes and wholesales best-selling chemical products in the consumer market, enjoying a high position among consumers. The company has established long-term and stable cooperative relationships with multiple retailers and agents. The company was founded in 2012 and has a sales history of over 10 years. There are around 160 employees. Hebei Shunxing Import and Export Co., Ltd. operates a complete range of chemical products at reasonable prices. Our company has strong strength, values credit, abides by contracts, and guarantees product quality. With the characteristics of diversified business and the principle of small profits and quick sales, we have gained the trust of more and more customers. In today's increasingly transparent product prices, our company has won the trust of our customers with its thoughtful service and excellent product quality, and has established a mutually beneficial cooperative relationship with them. The company will continue to make friends from all walks of life in an honest and mutually beneficial manner, warmly welcoming friends from all walks of life。
The company's main products are HPMC, PM, MDEA, LAS60%, Tween (R) 80, EDTA,white oil and so on.Most of them belong to general organic chemicals

Inquiry History

3 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	beta arbutin	2.00 KG	Nov 5, 2025
Brazil	Arbutin	1 20' Fcl	Nov 28, 2024
India	Beta arbutin	100.00 KG	Jul 4, 2024

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Arbutin CAS 497-76-7 Best Price Cosmetic Raw Material Pure Natural Hot

Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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