 Home > Active Pharmaceutical Ingredients > Other Chemical Drugs > Duloxetine hydrochloride for Sale > High Quality 99% Duloxetine HCL CAS 136434-34-9 Powder Fast Shipment Good Price

High Quality 99% Duloxetine HCL CAS 136434-34-9 Powder Fast Shipment Good Price buy - large image1

High Quality 99% Duloxetine HCL CAS 136434-34-9 Powder Fast Shipment Good Price buy - image1

High Quality 99% Duloxetine HCL CAS 136434-34-9 Powder Fast Shipment Good Price buy - image2

High Quality 99% Duloxetine HCL CAS 136434-34-9 Powder Fast Shipment Good Price

Name: High Quality 99% Duloxetine HCL CAS 136434-34-9 Powder Fast Shipment Good Price
Brand: HyperChem
SKU: pr2412111284
Price: 200 USD
Availability: InStock

TDS 1 Inquiries

Unit Price: Get Latest Price 

CAS No.:

136434-34-9

Grade:

Pharmaceutical Grade

Content:

99.5%

Port:

Hangzhou

Brand:

HyperChem

Packaging:

1kg/Bag

Price valid (until):

2025-01-11

Contact Supplier

 Chat Now

Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

 Visit Store

Product Description
Seller Information
Inquiry History

Description

Name	Duloxetinel HCL
CAS number	136434-34-9
Synonym	Duloxetine; Cymbalta; (S)-Duloxetine; Yentreve; LY-227942; LY-248686;
Description	(S)-Duloxetine HCl is a serotonin and norepinephrine reuptake inhibitor. It is mostly prescribed for major depressive disorder, generalized anxiety disorder, fibromyalgia and neuropathic pain. Duloxetine is sold under the brand name Cymbalta among others. It is also used in the treatment of stress urinary incontinence.
Structure
Molecular Formula	C18H20ClNOS
Molecular Weight	333.88 g/mol
Appearance	White Powder
Quality Standard	99%
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Dry, dark and at 2~8 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag, Bottle
Commercial package	Aluminium Tin
Origin	China

Duloxetine HCL More Info

Duloxetine hydrochloride is a medication primarily used to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), fibromyalgia, and chronic pain conditions such as diabetic neuropathic pain and chronic musculoskeletal pain. It belongs to a class of drugs known as serotonin-norepinephrine reuptake inhibitors (SNRIs). Below is a detailed overview of this product:

Mechanism of Action

Duloxetine works by inhibiting the reuptake of two neurotransmitters in the brain: serotonin and norepinephrine. By increasing the availability of these neurotransmitters, Duloxetine helps improve mood, alleviate anxiety, and relieve pain. The modulation of both serotonin and norepinephrine pathways contributes to its efficacy in treating depression, anxiety, and pain conditions.

Indications

Duloxetine is indicated for:

Major Depressive Disorder (MDD): Used to manage symptoms of depression in adults.

Generalized Anxiety Disorder (GAD): Effective in reducing anxiety symptoms in adults.

Fibromyalgia: Approved for the management of fibromyalgia, a chronic pain condition.

Chronic Pain Disorders: Used to treat neuropathic pain associated with diabetic peripheral neuropathy as well as chronic musculoskeletal pain.

Dosing and Administration

Duloxetine is typically administered orally in the form of capsules. The common dosing regimen includes:

Initial Dose: For conditions like MDD and GAD, the usual starting dose is 30 mg to 60 mg once daily.

Maintenance Dose: Depending on the indication and patient response, the dose may be increased to a maximum of 120 mg per day, given in one or two divided doses.

Side Effects

Common side effects associated with Duloxetine include:

Gastrointestinal Issues: Nausea, dry mouth, constipation, and decreased appetite are frequently reported.

Central Nervous System Effects: Patients may experience dizziness, drowsiness, or fatigue.

Increased Sweating: Hyperhidrosis or excessive sweating can occur.

Sexual Dysfunction: Some individuals may have reduced libido or other sexual side effects.

Withdrawal Symptoms: Sudden discontinuation may lead to withdrawal symptoms such as headache, nausea, and irritability.

Contraindications and Precautions

Contraindications: Duloxetine should not be used in individuals with a known hypersensitivity to the drug. It is also contraindicated in patients taking monoamine oxidase inhibitors (MAOIs) or in those with uncontrolled narrow-angle glaucoma.

Precautions: Caution is advised in patients with a history of liver disease, renal impairment, or a history of bipolar disorder. Regular monitoring for suicidal thoughts or worsening depression is important, particularly in younger patients.

Conclusion

Duloxetine hydrochloride is an effective treatment option for various mental health conditions and chronic pain syndromes, working through the dual inhibition of serotonin and norepinephrine reuptake. While it can significantly improve symptoms and enhance the quality of life for many patients, careful consideration of potential side effects and contraindications is essential for safe and effective use. Patients are advised to collaborate closely with healthcare professionals to monitor their treatment progress and adjust dosages as necessary.

Product Image

Shop High Quality Oxytocin CAS 50-56-6-Detailed Image 2

Shop USP Quality Standard API Finasteride Powder with CAS 98319-26-7-Detailed Image 3

FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
LC at sight
DP at sight

Bank transfer

PayPal

Bitcoin...

Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express
FedEx UPS DHL EMS
Fast: 3-7 days around, high cost, door to door service

By Air
Suitable for more than 50kg
Fast: 3-7 days, hight cost, port to port, professional broker needed

By Sea
Suitable for more than 500kg
Fast: 7-45 days, low cost, port to port, professional broker needed

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders:
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders:
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Certificates

Basic Info

Product Name:

Duloxetine hydrochloride

Other Name:

2-Thiophenepropanamine,N-methyl-γ-(1-naphthalenyloxy)-,hydrochloride (1:1),(γS)-;2-Thiophenepropanamine,N-methyl-γ-(1-naphthalenyloxy)-,hydrochloride,(S)-;2-Thiophenepropanamine,N-methyl-γ-(1-naphthalenyloxy)-,hydrochloride,(γS)-;LY 248686 HCl;(S)-(+)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine hydrochloride;Duloxetine hydrochloride;Cymbalta;(S)-Duloxetine hydrochloride;(S)-(+)-Duloxetine hydrochloride;Dulane 20;(S)-γ-(1-Naphthalenoxy)-N-methylthiophene-2-propanamine monohydrochloride;(S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine hydrochloride;Yentreve;Irenka;Drizalma Sprinkle

CAS No.:

136434-34-9

Molecular Formula:

C18H19NOS.ClH

InChIKeys:

InChIKey=BFFSMCNJSOPUAY-LMOVPXPDSA-N

Molecular Weight:

333.88

Exact Mass:

333.095398

EC Number:

200-659-6

UNII:

9044SC542W

NSC Number:

759112|744012

DSSTox ID:

DTXSID9046443

NCI Thesaurus Code:

C65496

ATC Code:

N06AX21

HScode:

29349990

Categories:

Other Chemical Drugs

Characteristics

PSA:

49.50000

XLogP3:

5.82380

Appearance:

white to beige

Melting Point:

165-171 °C (polymorph)

Boiling Point:

466.2ºC at 760 mmHg

Flash Point:

9℃

Water Solubility:

H2O: soluble5mg/mL (clear solution, warmed)

Storage Conditions:

-20°C Freezer

Collision Cross Section:

168.9 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

See More Duloxetine hydrochloride Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Duloxetine hydrochloride Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Certifications:
Certification Report by Bureau Veritas

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
Pakistan	DULOXETINE HCL	2.00 KG	Feb 8, 2025

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Supplier Name	Details
API Duloxetine HCL Powder CAS 136434-34-9 Pharmaceutical Anti-99% Duloxetine HCL /Raw Material Duloxetine HCl	Pharmaceutical Grade/99	Hainan Flying International Trade Co., L	Inquiry
Duloxetine Hcl	Pharmaceutical Grade/	Shanghai Wonder Pharmaceutical Co.,Ltd	Inquiry
Duloxetine hydrochloride 98% purple crystalline 136434-34-9 Senwayer	Pharmaceutical Grade/98	Dingwang Technology (Wuhan) Co., Ltd.	Inquiry
Duloxetine hydrochloride	/99.00	HANGZHOU LEAP CHEM CO., LTD.	Inquiry
high purity hot sale (S)-Duloxetine hydrochloride 99% high quality see COA KANBEI	Industrial Grade/99	Henan Lihao Chem Plant Limited	Inquiry