 Home > Specialty Chemicals > Rapamycin for Sale > Wholesale Price 99% Purity Raw Material Powder 53123-88-9 Rapamycin

Wholesale Price 99% Purity Raw Material Powder 53123-88-9 Rapamycin

27 Inquiries

Unit Price: Get Latest Price 

CAS No.:

53123-88-9

Grade:

Industrial Grade

Content:

99.9%

Port:

qingdao

Packaging:

25kg drum or as your requirement

Price valid (until):

2025-01-17

Contact Supplier

 Chat Now

Hebei Runxuchen trading Co., LTD

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

peptide

 Visit Store

Product Description
Seller Information
Inquiry History

Description

Product Detail

Rapamycin is produced by the soil bacterium Streptomyces hygroscopicus. The drug's name comes from Rapa Nui, the indigenous name of Easter Island, where the compound was originally discovered in soil samples in the 1970s.

Sirolimus, also known as rapamycin, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection and treat a rare lung disease called lymphangioleiomyomatosis. It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants.

Application:

Rapamycin is a triene macrolide antibiotic, which demonstrates anti-fungal, anti-inflammatory, anti-tumor and immunosuppressive properties. Rapamycin has been shown to block T-cell activation and proliferation, as well as, the activation of p70 S6 kinase and exhibits strong binding to FK-506 binding proteins.

Rapamycin also inhibits the activity of the protein, mTOR, (mammalian target of rapamycin) which functions in a signaling pathway to promote tumor growth. Rapamycin binds to a receptor protein (FKBP12) and the rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signaling pathway.

ECHEMI Editorial Reference

Rapamycin (Sirolimus) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM.

Basic Info

Product Name:

Rapamycin

Other Name:

Rapamycin;23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine,rapamycin deriv.;Antibiotic AY 22989;[3S-[3R*[S*(1R*,3S*,4S*)],6S*,7E,9S*,10S*,12S*,14R*,15E,17E,19E,21R*,23R*,26S*,27S*,34aR*]]-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone;23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-,[3S-[3R*[S*(1R*,3S*,4S*)],6S*,7E,9S*,10S*,12S*,14R*,15E,17E,19E,21R*,23R*,26S*,27S*,34aR*]]-;(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone;AY 22989;(-)-Rapamycin;Sirolimus;SIIA 9268A;Rapamune;Rapammune;RPM;NSC 226080;RAPA;Wy 090217;Cypher;Nab rapamycin;Supralimus;14S-Rapamycin;Cypher Bx Velocity;PNP-sirolimus;DE 109;MS-RO01;MS-RO02;MS-RO03;Perceiva;Rapamysin;SVP-R;1179372-35-0;1189166-54-8;1233221-34-5;1353039-01-6

CAS No.:

53123-88-9

Molecular Formula:

C51H79NO13

InChIKeys:

InChIKey=QFJCIRLUMZQUOT-HPLJOQBZSA-N

Molecular Weight:

914.18

Exact Mass:

914.17

EC Number:

262-640-9

HScode:

2942000000

Categories:

Characteristics

PSA:

195

XLogP3:

Appearance:

yellow solid

Density:

1.2±0.1 g/cm3

Melting Point:

183-185 °C

Boiling Point:

973°C at 760 mmHg

Flash Point:

87 °C

Refractive Index:

1.551

Water Solubility:

soluble in DMSO at 50mg/ml or methanol at 25mg/ml. soluble in alcohol, dimethyl sulfoxide and dimethyl formamide. Insoluble in water.ethanol: soluble 2 MM

Storage Conditions:

-20°C

Vapor Pressure:

0.56 hPa ( 20 °C)

Toxicity:

LD50 in mice (mg/kg): 600 i.p.; >2,500 orally (Vézina)

Specific rotation:

D25 -58.2° (methanol)

See More Rapamycin Properties 

Hazard Identification

Classification of the substance or mixture

Carcinogenicity, Category 2

Reproductive toxicity, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H351 Suspected of causing cancer H361 Suspected of damaging fertility or the unborn child H372 Causes damage to organs through prolonged or repeated exposure
Prevention	P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Rapamycin Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
peptide

Location:
south road and north road

Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2022
Hebei runxuchen trading Co., Ltd. is a modern and advanced enterprise specializing in the production and export of peptide products, synthetic peptides, cosmetic raw materials, beauty and slimming products etc Products are widely used in health products, peptides and other fields. Our plant covers an area of 1000 m². The proposed workshop will be built according to GMP standards. We provide our customers with quality products and first-class service. Now, we can provide G-KG service to our customers.
High-Quality Peptides: Our company specializes in premium-grade peptides, ensuring the highest standards of purity and efficacy. Each product undergoes rigorous testing to guarantee superior quality and performance.

Cutting-Edge Technology: We leverage the latest advancements in peptide synthesis and production technology. Our state-of-the-art facilities and innovative processes enable us to deliver peptides with exceptional precision and consistency.

Custom Solutions: We offer tailored peptide solutions to meet the specific needs of our clients. Whether you require bespoke formulations or custom quantities, our experienced team is dedicated to providing personalized support and solutions.

Extensive Expertise: With years of experience in the peptide industry, our team of experts is well-versed in the complexities of peptide development and applications. We are committed to providing insightful guidance and technical support to help you achieve your goals.

Comprehensive Product Range: Our diverse portfolio of peptide products covers a wide range of applications, including research, pharmaceutical development, and cosmetic formulations. This allows us to cater to various industries and meet different customer needs.

Inquiry History

27 Inquiries

Country	Product	Purchase Quantity	Date Posted
Hungary	Raw Pharmaceutical Grade Material Rapamycin Powder CAS 53123-88-9 with High Purity	100 G	Nov 20, 2023
India	Raw Pharmaceutical Grade Material Rapamycin Powder CAS 53123-88-9 with High Purity	1000 MT	Nov 18, 2023
Germany	Raw Pharmaceutical Grade Material Rapamycin Powder CAS 53123-88-9 with High Purity	100 G	Sep 7, 2023
United States	TNJONE High quality GMP Certificated 99% Purity Sirolimus Rapamycin 53123-88-9 in Stock	1 G	Jan 1, 2025
United States	Rapamycin Powder	2 KG	Aug 25, 2023
Paraguay	Rapamycin Sirolimus Powder	1 G	Feb 21, 2024
India	Rapamycin	1 MT	Feb 12, 2026
India	Rapamycin	1.00 KG	Jan 26, 2024
United States	Rapamycin	50 MG	Apr 17, 2026
United States	rapamycin	100 G	Sep 27, 2025
Philippines	Rapamycin	5 G	Feb 10, 2025
Australia	Rapamycin	99 KG	Nov 3, 2024
United States	Rapamycin	10 MT	May 22, 2024
Canada	Rapamycin	1 KG	Jan 24, 2025
United States	Rapamycin	1 KG	Nov 27, 2024
United States	rapamycin	1 G	Jul 12, 2024
India	Rapamycin	1 KG	Jun 28, 2024
United States	Rapamycin	1 KG	Apr 14, 2025
Canada	Rapamycin	100 MG	Mar 4, 2025
Spain	Rapamycin	1 20' Fcl	Dec 16, 2024

Go to Page

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Price	Supplier Name	Details
Rapamycin 53123-88-9	Pharmaceutical Grade/99		Hainan Flying International Trade Co., L	Inquiry
High quaity Supply Medical Grade High Purity Rapamycin Powder CAS 53123-88-9 Rapamycin	Top Product/0		Shandong Airuike Chemical Co., Ltd.	Inquiry
Rapamycin	/95		Creative Enzymes	Inquiry
Pharmaceutical Grade Rapamycin Sirolimus 53123-88-9 with Factory Price	Pharmaceutical Grade/99	$30-34/G EXW	Wuhan Oner Biotech Co.,Ltd.	Inquiry
Rapamycin 53123-88-9	/		Guangzhou Yaoguang Technology Co., Ltd.	Inquiry