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Home > Active Pharmaceutical Ingredients > Circulatory System Drugs > Rapamycin for Sale > Pharmaceutical Grade Rapamycin Sirolimus 53123-88-9 with Factory Price
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Pharmaceutical Grade Rapamycin Sirolimus 53123-88-9 with Factory Price

28 Inquiries

Unit Price: Get Latest Price
CAS No.:

53123-88-9

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai, Beijing

Brand:

ONERBIO

Packaging:

25KG/drum

Price valid (until):

2026-06-27

Company Type:
Distributor
Location:
China
Qualification:
Main Products:

Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


    img

    Product Name: Rapamycin
    Synonyms: Sirolimus, Rapa
    CAS: 53123-88-9
    MF: C51H79NO13
    MW: 914.19
    EINECS: 610-965-5
    Appearance: Almost white powder

    Rapamycin (Rapa, or Sirolimus) is a new form of macrolide immunosuppressive agent. It is a white solid crystal.
    Its melting point is 183-185℃ and it is lipophilic. It is soluble in methanol, ethanol, acetone, chloroform, and other
    organic solvents, very slightly soluble in water, and almost insoluble in ether. It was first discovered in 1975 on the
    Chilean Easter Island as a secondary metabolite secreted by soil Streptomyces, and its chemical structure is that of
    a three-polyene macrolide compound.
    img


    img


    Product Name

    Magnesium Clycinate

    Quantity

    20kg

    Batch Number

    ONB20210011

    MFG Date

    2021.10.22

    Standard

    In house

    Expiry Date

    Two years


    Items

    Quality Standard

    Results

    Appearance

    White to off-white crystalline powder

    Conforms

    Purity

    ≥99.5%

    99.787%

    Hydroquinone PPM

    Negative

    Negative

    Melting point ℃

    202-207

    204.7-205.5

    Specific rotation °

    (a)20D=+174.0°~ +186.0°

    +179.45°

    Solubility

    Soluble in water slightly soluble in ethanol

    Conforms

    Residue on ignition

    ≤0.5%

    0.02%

    Loss on drying

    ≤0.5%

    0.13%

    PH

    5.0~7.0

    6.2

    Heavy metals(Pb)

    ≤10ppm

    Conforms

    Arsenic

    ≤2ppm

    Conforms

    Total Plate Count(CFU/g)

    ≤100

    Conforms

    Yeast and Mold(CFU/g)

    ≤50

    Conforms

    E.Coliforms(CFU/g)

    Negative

    Conforms

    Staphylococcus aureus(CFU/g)

    Negative

    Negative

    P.aeruginosa(CFU/g)

    Negative

    Negative

    Conclusion

    The product conforms to In-house standard

    img

    As an mTOR inhibitor, sirolimus has a broad spectrum of activity that has demonstrated the ability to inhibit
    inflammation, proliferation, angiogenesis, fibrosis, and hyperpermeability. Sirolimus currently has multiple uses
    in the prevention of rejection in organ transplantation and, recently, in the treatment of advanced renal cell carcinoma.
    Sirolimus-eluting cardiac stents have been shown to limit the rate of overgrowth of tissue and thus prevent coronary
    restenosis. Early studies suggest that it may be an effective agent for controlling severe uveitis and that it may also
    have a role in treating agerelated macular degeneration.
    img

    Basic Info
    Product Name:

    Rapamycin

    Other Name:

    Rapamycin;23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine,rapamycin deriv.;Antibiotic AY 22989;[3S-[3R*[S*(1R*,3S*,4S*)],6S*,7E,9S*,10S*,12S*,14R*,15E,17E,19E,21R*,23R*,26S*,27S*,34aR*]]-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone;23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-,[3S-[3R*[S*(1R*,3S*,4S*)],6S*,7E,9S*,10S*,12S*,14R*,15E,17E,19E,21R*,23R*,26S*,27S*,34aR*]]-;(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone;AY 22989;(-)-Rapamycin;Sirolimus;SIIA 9268A;Rapamune;Rapammune;RPM;NSC 226080;RAPA;Wy 090217;Cypher;Nab rapamycin;Supralimus;14S-Rapamycin;Cypher Bx Velocity;PNP-sirolimus;DE 109;MS-RO01;MS-RO02;MS-RO03;Perceiva;Rapamysin;SVP-R;1179372-35-0;1189166-54-8;1233221-34-5;1353039-01-6

    CAS No.:

    53123-88-9

    Molecular Formula:

    C51H79NO13

    InChIKeys:

    InChIKey=QFJCIRLUMZQUOT-HPLJOQBZSA-N

    Molecular Weight:

    914.18

    Exact Mass:

    914.17

    EC Number:

    262-640-9

    HScode:

    2942000000

    Characteristics
    PSA:

    195

    XLogP3:

    6

    Appearance:

    yellow solid

    Density:

    1.2±0.1 g/cm3

    Melting Point:

    183-185 °C

    Boiling Point:

    973°C at 760 mmHg

    Flash Point:

    87 °C

    Refractive Index:

    1.551

    Water Solubility:

    soluble in DMSO at 50mg/ml or methanol at 25mg/ml. soluble in alcohol, dimethyl sulfoxide and dimethyl formamide. Insoluble in water.ethanol: soluble 2 MM

    Storage Conditions:

    -20°C

    Vapor Pressure:

    0.56 hPa ( 20 °C)

    Toxicity:

    LD50 in mice (mg/kg): 600 i.p.; >2,500 orally (Vézina)

    Specific rotation:

    D25 -58.2° (methanol)

    Hazard Identification

    Classification of the substance or mixture

    Carcinogenicity, Category 2

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H351 Suspected of causing cancer

    H361 Suspected of damaging fertility or the unborn child

    H372 Causes damage to organs through prolonged or repeated exposure

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

    Location:

    Changqing 5th Road, Jianghan District

    Payment Terms:

    TT against copy of documents

    Average lead Time:

    5

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    5-10

    Year of Establishment:

    2020

    Wuhan Oner Biotech Co.,Ltd. located in the popular city of Wuhan, specilize in producing and developing pharmaceutical & its intermediates, Cosmetics Raw Material and Intermediate, food additive, Plant extracts,and in distributing the products of our own company. We serves our clients by supplying high-quality.These products are manufactured in ISO 9001 certified plants and have continuously been passing quality inspection by CIQ (China Entry & Exit Inspection and Quarantine Bureau),100% pass rate. Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , the products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. With constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

  • Inquiry History
    28 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Supply Medical Grade High Purity Rapamycin Powder CAS 53123-88-9 Rapamycin

    100 G Aug 16, 2023
    Germany

    Raw Pharmaceutical Grade Material Rapamycin Powder CAS 53123-88-9 with High Purity

    100 G Sep 7, 2023
    Hungary

    Raw Pharmaceutical Grade Material Rapamycin Powder CAS 53123-88-9 with High Purity

    100 G Nov 20, 2023
    India

    Raw Pharmaceutical Grade Material Rapamycin Powder CAS 53123-88-9 with High Purity

    1000 MT Nov 18, 2023
    United States

    TNJONE High quality GMP Certificated 99% Purity Sirolimus Rapamycin 53123-88-9 in Stock

    1 G Jan 1, 2025
    United States

    Rapamycin Powder

    2 KG Aug 25, 2023
    Paraguay

    Rapamycin Sirolimus Powder

    1 G Feb 21, 2024
    India

    Rapamycin

    1 MT Feb 12, 2026
    India

    Rapamycin

    1.00 KG Jan 26, 2024
    United States

    Rapamycin

    50 MG Apr 17, 2026
    United States

    rapamycin

    100 G Sep 27, 2025
    Philippines

    Rapamycin

    5 G Feb 10, 2025
    Australia

    Rapamycin

    99 KG Nov 3, 2024
    United States

    Rapamycin

    10 MT May 22, 2024
    Canada

    Rapamycin

    1 KG Jan 24, 2025
    United States

    Rapamycin

    1 KG Nov 27, 2024
    United States

    rapamycin

    1 G Jul 12, 2024
    India

    Rapamycin

    1 KG Jun 28, 2024
    United States

    Rapamycin

    1 KG Apr 14, 2025
    Canada

    Rapamycin

    100 MG Mar 4, 2025
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