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Home > Active Pharmaceutical Ingredients > Other Chemical Drugs > Clobetasol propionate for Sale > High Quality Clobetasol Propionate CAS 25122-46-7 Powder Fast Shipping Good Price
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High Quality Clobetasol Propionate CAS 25122-46-7 Powder Fast Shipping Good Price

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Unit Price: Get Latest Price
CAS No.:

25122-46-7

Grade:

Pharmaceutical Grade

Content:

99.5%

Port:

Hangzhou

Brand:

HyperChem

Packaging:

1kg/Bag

Price valid (until):

2025-01-24

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Name

    Clobetasol Propionate

    CAS number

    25122-46-7

    Synonym

    CCl-4725; CCl 4725; CCl4725; CGP 9555; CGP9555; CGP-9555; Clobetasol 17-Propionate;

    Description

    Clobetasol propionate is a corticosteroid used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis caused by exposure to poison ivy/oak. Clobetasol belongs to US Class I (Europe: class IV) of the corticosteroids, making it one of the most potent available. It comes in shampoo, mousse, ointment and emollient cream presentations. It has very high potency and typically should not be used with occlusive dressings, or for extended continuous use (beyond two weeks). I

    Structure

    Shop High Quality Clobetasol Propionate CAS 25122-46-7 Powder Fast Shipping Good Price-Detailed Image 1

    Molecular Formula

    C25H32ClFO5

    Molecular Weight

    466.97 g/mol

    Appearance

    White Powder

    Quality Standard

    99%

    Shipping Condition

    Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

    Storage Condition

    Dry, dark and at 2~8 for short term (days to weeks) or -20 for long term (months to years).

    Shelf Life

    >2 years if stored properly

    Sample package

    Aluminium foil bag, Bottle

    Commercial package

    Aluminium Tin

    Origin

    China

    Clobetasol Propionate More Info

    

    

    Clobetasol Propionate is a highly potent topical corticosteroid used primarily in dermatology for the treatment of various inflammatory skin conditions. It is known for its strong anti-inflammatory, antipruritic (anti-itch), and vasoconstrictive properties. Here are the key aspects of Clobetasol Propionate:

     

    Mechanism of Action

    Clobetasol Propionate works by binding to corticosteroid receptors in the cells, leading to the inhibition of inflammatory mediators such as cytokines and chemokines. This action decreases the inflammatory response and alleviates symptoms associated with skin conditions, such as redness, swelling, and itching. The prompt effect of clobetasol propionate makes it effective for treating acute exacerbations of skin diseases.

     

    Indications

    Clobetasol Propionate is indicated for the treatment of a variety of dermatological conditions, including:

     

    Psoriasis: Particularly effective in managing plaque psoriasis.

    Eczema: Used for atopic dermatitis and other forms of dermatitis that require stronger management.

    Lichen Planus: A condition characterized by itchy, purplish, flat-topped bumps on the skin.

    Seborrheic Dermatitis: It can help reduce inflammation and scaling.

    Other Inflammatory Skin Conditions: It is also used in the treatment of conditions characterized by significant inflammation and pruritus.

    Dosage and Administration

    Clobetasol Propionate is available in various formulations, including:

     

    Topical Cream: Applied directly to the affected areas of the skin.

    Ointment: A thicker formulation that may help with more severe skin conditions.

    Gel: Often used for hairy areas where creams or ointments may not be suitable.

    Foam: Provides a convenient way to apply the medication, particularly for larger areas.

    The dosage generally involves applying a thin layer to the affected area one to two times daily, depending on medical advice. Treatment typically should be limited to a short duration (usually not exceeding two weeks) due to the high potency of the medication and the risk of skin atrophy with long-term use.

     

    Side Effects

    While Clobetasol Propionate is effective, it can cause side effects, especially with prolonged use or on large body surface areas. Common side effects include:

     

    Skin Irritation: Burning, itching, or stinging at the application site.

    Thinning of the Skin: Prolonged use may lead to atrophy or thinning of the skin in the treated areas.

    Tachyphylaxis: Reduced efficacy with prolonged use may be observed.

    Systemic Effects: Although rare, systemic absorption can lead to adrenal suppression, particularly in pediatric patients or following extensive applications.

    Contraindications and Precautions

    Infections: Clobetasol Propionate should not be used on infected skin, including viral, bacterial, or fungal infections, unless these are treated concurrently.

    Pregnancy and Lactation: Use during pregnancy and breastfeeding should be approached with caution and under the guidance of a healthcare professional.

    Dermatitis: Clobetasol should not be used in the treatment of acne vulgaris or rosacea.

    Ocular Use: It is contraindicated for use in the eyes, as it can cause glaucoma or cataracts.

    Conclusion

    Clobetasol Propionate is an effective topical corticosteroid for managing inflammatory skin conditions, known for its potency and rapid action. Its use should be balanced against potential side effects, particularly with long-term applications. Patients are advised to follow their healthcare provider's instructions closely to achieve the best results while minimizing risks. Monitoring for side effects is crucial, especially in sensitive populations like children.


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    FAQ


    Q1. Can I get a free sample?

    We can send you a samll free sample, and you only need to pay for the shipping cost.

     

    Q2. What is the HyperChem payment term?

    T/T in advance
    LC at sight
    DP at sight

    Bank transfer

    PayPal

    Bitcoin...

     

    Q3. What is HyperChem shipment policy?

    Our policy is to strive for the quickest shipment time possible.

    For ready stock samples, they are usually shipped within 3 working days after payment received.
    For non-ready stock, please contact HyperChem sales team to negotiate.

     

    Q4. What is HyperChem shipment term?

    By Express  
    FedEx  UPS  DHL  EMS                               
    Fast: 3-7 days around, high cost, door to door service

    By Air                                        
    Suitable for more than 50kg 
    Fast: 3-7 days, hight cost, port to port, professional broker needed 

    By Sea
    Suitable for more than 500kg      
    Fast: 7-45 days, low cost, port to port, professional broker needed 

     

    We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

     

    Q5. What HyperChem will provide after shipment?

    For sample orders: 
    After shipment is done, an timely email including:

    1. Track details (Fedex /TNT/DHL/EMS Track number)
    2. Packaging photo
    3. COA, MSDS, etc
    4. Dispatch date & Estimated arriving time
    5. Shipping invoice

    For commercial orders:
    A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

    Certificates

    Basic Info
    Product Name:

    Clobetasol propionate

    Other Name:

    Pregna-1,4-diene-3,20-dione,21-chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-,(11β,16β)-;Pregna-1,4-diene-3,20-dione,21-chloro-9-fluoro-11β,17-dihydroxy-16β-methyl-,17-propionate;(11β,16β)-21-Chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione;21-Chloro-21-deoxybetamethasone 17-propionate;Dermovate;Clobetasol propionate;Clobetasol 17-propionate;CGP 9555;Clobesol;Temovate;Clobederm;GR 2/925;Dermoxin;Dermoxinale;Dermoval;CCl 4725;Karison;Clobex;Olux;Skin Cap;Olux-E;Tenovate

    CAS No.:

    25122-46-7

    Molecular Formula:

    C25H32ClFO5

    InChIKeys:

    InChIKey=CBGUOGMQLZIXBE-XGQKBEPLSA-N

    Molecular Weight:

    466.97000

    Exact Mass:

    466.97

    EC Number:

    246-634-3

    UNII:

    779619577M

    DSSTox ID:

    DTXSID6045907

    NCI Thesaurus Code:

    C28934

    HScode:

    2937290090

    Categories:

    Other Chemical Drugs

    Characteristics
    PSA:

    80.67000

    XLogP3:

    4.10310

    Appearance:

    White Crystalline Powder

    Density:

    1.28 g/cm3

    Melting Point:

    195.5-197 °C

    Boiling Point:

    569ºC at 760 mmHg

    Flash Point:

    297.9ºC

    Refractive Index:

    1.56

    Vapor Pressure:

    2.58E-15mmHg at 25°C

    Collision Cross Section:

    205.1 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 1B

    Specific target organ toxicity – repeated exposure, Category 2

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 4

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H360 May damage fertility or the unborn child

    H373 May cause damage to organs through prolonged or repeated exposure

    H413 May cause long lasting harmful effects to aquatic life

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P273 Avoid release to the environment.

    Response

    P318 IF exposed or concerned, get medical advice.

    P319 Get medical help if you feel unwell.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

  • Inquiry History
    3 Inquiries
    Country Product Purchase Quantity Date Posted
    Trinidad and Tobago

    Clobetasol propionate 99% white powder 25122-46-7 Senwayer

    1 KG Dec 4, 2023
    United States

    Clobetasol propionate

    5 G Sep 2, 2025
    Pakistan

    Clobetasol Propionate

    2 KG Dec 17, 2025
    Post an enquiry for this product
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