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Hair Loss Treatment Ingredients Fevipiprant Qaw039 Powder CAS 872365-14-5 for sale

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CAS No.:

872365-14-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

QINGDAO

Brand:

Packaging:

1kg ,25kg or according to customer's detail requirement.

Price valid (until):

2025-05-31

Contact Supplier

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Nanjing Huaman Import and Exp

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Propylene glycol

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Product Description
Seller Information

Description

Product Detail

Hair Loss Treatment Ingredients Fevipiprant Qaw039 Powder CAS 872365-14-5

What is Fevipiprant /Qaw039 ?

Fevipiprant, also known as NVP-QAW039 or QAW039, is an oral active and potent CRTh2 receptor antagonist and potentially useful for asthma treatment. [(3)H]-QAW039 displayed high affinity for the human CRTh2 receptor (1.14 ± 0.44 nM) expressed in Chinese hamster ovary cells, the binding being reversible and competitive with the native agonist prostaglandin D2(PGD2). QAW039 was also a potent inhibitor of PGD2-induced cytokine release in human Th2 cells. Fevipiprant reduces eosinophilic airway inflammation and is well tolerated in patients with persistent moderate-to-severe asthma and raised sputum eosinophil counts despite inhaled corticosteroid treatment. Fevipiprant demonstrates a favorable safety profile.

Fevipiprant, a drug primarily used to treat asthma, has recently been explored for its potential use in hair care. There is evidence to suggest a link between hair loss and inflammation in the scalp, and fevipiprant's anti-inflammatory properties could provide benefits for those experiencing hair loss or thinning.

Studies have shown that fevipiprant can reduce levels of certain inflammatory molecules in the scalp which contribute to hair loss. This suggests that fevipiprant could potentially be used as a preventative treatment for hair loss, particularly in individuals with underlying inflammatory scalp conditions.

Furthermore, fevipiprant may also promote hair growth. A study conducted on mice showed that treatment with fevipiprant increased hair growth and thickness compared to a control group. While more research is needed to determine its effectiveness in humans, these preliminary findings suggest that fevipiprant could have a positive impact on hair growth.

Items	Specifications
Product Name	Fevipiprant /Qaw039
CAS No.	872365-14-5
Appearance	white powder
Assay	98%
MF	C19H17F3N2O4S
MW	426.41
Melting Point	637.6±55.0 °C(Predicted)
Density	1.44±0.1 g/cm3(Predicted)

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Certification

Technical Date Sheet:

Test Items	Test Standards	Test Results
Description	White or off-white crystalline powder	White crystalline powder
Identification	Positive	Positive
Loss on drying	≤0.5%	0.15%
Residue on ignition	≤0.5%	0.05%
Heavy metals	≤20ppm	5ppm
Organic volatile impurities	Accord with USP41 requirement	Complies
Total impurities	≤1.5%	<1.5%
Purity	97.0%~103.0%	99.45%
Conclusion: This batch of product complies with the standard of USP41.

Application Fevipiprant is the for the treatment of hair loss dwindled, perhaps due more to commercial potential and chemical stability reasons than efficacy as the later studies of Setipiprant have focused on different chemical forms of the combining it with various nanoparticles to enhance delivery.

Fevipiprant reduces eosinophilic airway inflammation and is well tolerated in patients with persistent moderate-to-severe asthma and raised sputum eosinophil counts despite inhaled corticosteroid treatment. Fevipiprant demonstrates a favorable safety profile.

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Our advantage ：

★ The company has been established for more than 10 years with rich export experience and experienced transportation team.

★ Awesome after sales.1 to 1 customer service to solve any problems from the beginning of the inquiry to the receipt of goods

★ Quality is guaranteed.

Shipping Advise

1. By Express

------Suitable for under 50kg, Fast:3-7 days.

High cost; Door to door service. Easy to pick up the goods.

2. By Air

------Suitable for more than 50 kg, Fast:3-7 days,

High cost, airport to airport. professional broker needed.

3. By sea

------Suitable for more than 500kg. Slow: 5-45 days,

Low cost. Port to Port, professional broker needed.

Service

1. Any inquiries will be replied within 24 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & formulation development.

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Certificates

Basic Info

Product Name:

Fevipiprant

Other Name:

Fevipiprant;Fevipipran;NVP-QAW039;Fevipiprant(NVP-QAW039);QAW039;Fevipiprant (QAW039);2-Methyl-1-[[4-(methylsulfonyl)-2-(trifluoromethyl)phenyl]methyl]-1H-pyrrolo[2,3-b]pyridine-3-acetic acid;CS-2449

CAS No.:

872365-14-5

Molecular Formula:

C19H17F3N2O4S

InChIKeys:

GFPPXZDRVCSVNR-UHFFFAOYSA-N

Molecular Weight:

426.41

Exact Mass:

426.086113 g/mol

UNII:

2PEX5N7DQ4

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

97.6

XLogP3:

2.8

Density:

1.44±0.1 g/cm3(Predicted)

See More Fevipiprant Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Fevipiprant Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Propylene glycol

Location:
No .41 Optics Valley Avenue, East Lake High-tech Development Zone, Wuhan ,China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment

Average lead Time:
5

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2024

Nanjing Huaman Import and Export Co., Ltd was established in 2024 with strong research and development capabilities and superb synthesis technology, as well as advanced quality control measures. Effectively promote the joint venture and cooperation with the major enterprises, manufacturers, with the idea of industrial development to serve the society and the majority of users. We always adhere to the market demand as the orientation, constantly synthesizing new high-tech chemical products , mainly exported to the United States, Europe, India, South Africa, Nigeria and other countries and regions, has a wealth of export experience, to ensure transportation safety, can let each customer as soon as possible to safely receive the goods.
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