High Quality EP Standard 99% White Powder Ciprofibrate CAS 52214-84-3 with good price and fast delivery

Ciprofibrate More Info

Ciprofibrate is a lipid-regulating medication classified as a fibrate, primarily used to manage hyperlipidaemia (elevated lipid levels in the blood). It is particularly effective in lowering triglycerides and increasing high-density lipoprotein (HDL) cholesterol levels. Ciprofibrate is available in tablet form and is typically prescribed when dietary and lifestyle changes alone are insufficient to control lipid levels.

Mechanism of Action

Ciprofibrate acts primarily as a peroxisome proliferator-activated receptor alpha (PPARα) agonist. Its mechanism involves:
Activation of PPARα: This activation leads to increased oxidation of fatty acids in the liver and muscle, promoting the breakdown of triglycerides.
Enhancement of Lipoprotein Lipase Activity: Ciprofibrate stimulates lipoprotein lipase, an enzyme that helps clear triglyceride-rich lipoproteins from the bloodstream.
Modulation of Apolipoproteins: It influences the expression of apolipoproteins, which are essential for lipid metabolism, thereby enhancing HDL cholesterol levels and reducing low-density lipoprotein (LDL) cholesterol.

Applications

Hyperlipidaemia: Particularly effective for patients with severe hypertriglyceridaemia and mixed dyslipidaemia, especially when statins are contraindicated or poorly tolerated.
Dyslipidaemia Management: Used as an adjunct therapy to diet and exercise for overall lipid management.

Routes of Administration

Ciprofibrate is administered orally in tablet form, typically prescribed at a dosage that may vary based on individual patient needs and lipid levels.

Safety and Side Effects

Common Side Effects
Patients taking ciprofibrate may experience:
Nausea
Diarrhea
Indigestion
Headaches
Dizziness or tiredness
Muscle aches or pains
Serious Side Effects
More severe adverse effects can include:
Myopathy or Rhabdomyolysis: Patients should be advised to report unexplained muscle pain or tenderness.
Liver Dysfunction: Symptoms may include jaundice (yellowing of skin or eyes), indicating potential liver damage.
Allergic Reactions: Such as rash, itching, or swelling.

Pharmacokinetics

Absorption and Distribution
Ciprofibrate is well absorbed from the gastrointestinal tract, with peak serum concentrations reached approximately one hour after ingestion. It has a long elimination half-life of about 80 hours, allowing for once-daily dosing.
Metabolism and Excretion
The drug is primarily metabolized in the liver and excreted through urine. Its pharmacokinetic properties make it suitable for managing chronic conditions like hyperlipidaemia effectively.

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
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Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express  
FedEx  UPS  DHL  EMS                               
Fast: 3-7 days around, high cost, door to door service

By Air                                        
Suitable for more than 50kg 
Fast: 3-7 days, hight cost, port to port, professional broker needed 

By Sea
Suitable for more than 500kg      
Fast: 7-45 days, low cost, port to port, professional broker needed 

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders: 
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.