R-Flurbiprofen factory
TDS 1 Inquiries
51543-40-9
Pharmaceutical Grade
99.6%
us
Million
25kg/Cardboard Drum
2025-08-25
Avanafil,Tirzepatide,Semaglutide,Pregabalin,Nootropics,MT2
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceTarenflurbil ((R)-Flurbiprofen) is the R-enantiomer of the racemate NSAID Flurbiprofen, Tarenflurbil ((R)-Flurbiprofen) inhibits the binding of [3H]9-cis-RA to RXRα LBD with IC50 of 75 μM.
(R)-flurbiprofen is a flurbiprofen. It is an enantiomer of a (S)-flurbiprofen.|Tarenflurbil is an investigational drug that was studied in patients with mild Alzheimer's disease. It is a selective amyloid lowering agent (SALA) that reduces levels of the toxic peptide amyloid beta 42 (Aβ42) in cultured human cells and in animal models. Aβ42 is the primary initiator of neurotoxicity and amyloid plaque development in the brains of Alzheimer's disease patients. In June 2008 development of the drug for Alzheimer's disease was discontinued. Tarenflurbil has also been used in trials studying the treatment of Prostate Cancer.|Tarenflurbil is an orally active synthetic enantiomer of flurbiprofen. Tarenflurbil activates c-Jun N terminal kinase, increases AP-1 binding to DNA, and downregulates cyclin D1 expression, resulting in arrest of tumor cells in the G1 phase of the cell cycle and apoptosis. This agent also affects the expression of nuclear factor kappa B, a rapid response transcription factor that stimulates the immune response to tumor cells. R-flurbiprofen does not inhibit the enzyme cyclo-oxygenase.CertificatesBasic Info-
Product Name:
(-)-Flurbiprofen
Other Name:[1,1′-Biphenyl]-4-acetic acid,2-fluoro-α-methyl-,(αR)-;[1,1′-Biphenyl]-4-acetic acid,2-fluoro-α-methyl-,(R)-;(αR)-2-Fluoro-α-methyl[1,1′-biphenyl]-4-acetic acid;(-)-Flurbiprofen;l-Flurbiprofen;R-(-)-Flurbiprofen;(-)-(R)-Flurbiprofen;(R)-Flurbiprofen;E 7869;MPC 7869;Tarenflurbil;Flurizan;(R)-(-)-2-(2-Fluorobiphenyl-4-yl)propionic acid;(R)-Flurbiprofen;(2R)-2-(3-Fluoro-4-phenylphenyl)propanoic acid
CAS No.:51543-40-9
UN No.:2811
Molecular Formula:C15H13FO2
InChIKeys:InChIKey=SYTBZMRGLBWNTM-SNVBAGLBSA-N
Molecular Weight:244.26100
Exact Mass:244.26
EC Number:257-264-7
UNII:501W00OOWA
NSC Number:685699
DSSTox ID:DTXSID40199508
NCI Thesaurus Code:C26666
HScode:2916399090
Categories:
Characteristics-
PSA:
37.30000
XLogP3:3.68080
Density:1.199 g/cm3
Melting Point:110-113ºC
Boiling Point:376.2ºC at 760 mmHg
Flash Point:181.3ºC
Refractive Index:1.34
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Avanafil,Tirzepatide,Semaglutide,Pregabalin,Nootropics,MT2
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Location:
Room 1-2208, Lianhecaifu Square, No2177, Tianchen Road, Gaoxin District, Jinan City, Shandong Province, China
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Payment Terms:
L/C,100% TT in advance
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Average lead Time:
3
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Total Annual Revenue:
$1 million-$2.5 million
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Total Employees:
11-50
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Year of Establishment:
2012
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Certifications:
business license
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted
Pakistan
(R)-2-Flubiprofen
100 KG Jul 31, 2025 Post an enquiry for this product
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