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supply CAS 117704-25-3 Antiparasitics Raw 99% Doramectin Powder for sale

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CAS No.:

117704-25-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

QINGDAO

Brand:

Packaging:

1kg,25kgor according to customer's detail requirement.

Price valid (until):

2025-06-27

Contact Supplier

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Nanjing Huaman Import and Exp

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Propylene glycol

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Product Description
Seller Information
Inquiry History

Description

Product Detail

CAS 117704-25-3 Antiparasitics Raw 99% Doramectin Powder

What is Doramectin?

Doramectin is obtained by fermenting a new strain of Streptomyce avermitilis. It is a broad-spectrum antiparasitic drug. It has a good repellent effect on internal and external parasites, especially some nematodes (roundworms) and arthropods, but it is not effective on tapeworms, flukes and protozoa. Its mechanism of action is mainly to increase the release of the inhibitory transmitter γ-aminobutyric acid (GABA) of the worm, thereby blocking the transmission of neural signals, causing muscle cells to lose their ability to contract, and causing the worm to die. The mammalian peripheral neurotransmitter is acetylcholine and is not affected by doramectin. Doramectin does not easily penetrate the blood-brain barrier, has minimal damage to the central nervous system, and is safer for livestock.

Items	Specifications
Product Name	Doramectin
Cas No	117704-25-3
Einecs	601-490-4
MF	C50H74O14
MW	899.11
Melting Point	116-119°C (dec.) (lit.)
Boiling Point	967.4±65.0 °C(Predicted)
Density	1.25±0.1 g/cm3(Predicted)
Appearance	White powder
Shelf Life	2 Years When Properly Stored
Storage	Keep in a cool, dry, dark location in a tightly sealed container or cylinder.

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Specification

Item	Specifications	Results
Appearance	White or off white crystalline powder	White crystalline powder
Identification	1,IR spectrum is consistent with CRS	Conforms
Identification	2,The retention time of the main peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the standard preparation. As obtained in the Assay.	Conforms
Clarity & color	Colorless and clear	Colorless and clear
Fluorides	≥12.0%	12.0%
Related substance	Individual impurity ≤0.5%	0.25%
Related substance	Total impurities ≤1.0%	0.63%
Loss on drying	≤0.5%	0.12%
Residue on ignition	≤0.1%	0.06%
Heavy metals	Not more than 10ppm	Conform
Assay (HPLC)	Not less than 98.0%	99.2%
Conclusion	The results conforms with Import Veterinary Drug standards

Function & Application
It is used for the treatment and control of internal parasitosis (gastrointestinal and pulmonary nematodes), ticks and mange (and other ectoparasites). Doramectin is a derivative of ivermectin. Its spectrum includes:Haemonchus spp., Ostertagia spp., Trichostrongylusspp., Cooperia spp., Oesophagostomum spp., Dictyocaulus viviparus, Dermatobia hominis, Boophilus microplus, Psoroptes bovis, among many other internal and external parasites. It is available in 2 dosage forms: as aninjection and as a 5 mg/ml topical solution.
Doramectin is effective against the major parasitic roundworms: gastrointestinal and pulmonary. It is also effecive against most mites and lice species, and against numerous myiases (e.g. those caused by screwworm flies, bot flies and warble flies) usually regardless of the delivery form As all macrocyclic lactone doramectin acts as agonist of the GABA (gamma-aminobutyric acid) neurotransmitter in nerve cells and also binds to glutamate-gated chloride channels in nerve and muscle cells of invertebrates. In both cases it blocks the transmission of neuronal signals of the parasites, which are either paralyzed and expelled out of the body, or they starve. It also affects the reproduction of some parasites by diminishing oviposition or inducing an abnormal oogenesis.

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Our advantage ：

★ The company has been established for more than 10 years with rich export experience and experienced transportation team.

★ Awesome after sales.1 to 1 customer service to solve any problems from the beginning of the inquiry to the receipt of goods

★ Quality is guaranteed.

Shipping Advise

1. By Express

------Suitable for under 50kg, Fast:3-7 days.

High cost; Door to door service. Easy to pick up the goods.

2. By Air

------Suitable for more than 50 kg, Fast:3-7 days,

High cost, airport to airport. professional broker needed.

3. By sea

------Suitable for more than 500kg. Slow: 5-45 days,

Low cost. Port to Port, professional broker needed.

Service

1. Any inquiries will be replied within 24 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & formulation development.

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Certificates

Basic Info

Product Name:

Doramectin

Other Name:

Avermectin A1a,25-cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)-;Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2′-[2H]pyran],avermectin A1a deriv.;25-Cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)avermectin A1a;Doramectin;UK 67994;25-Cyclohexylavermectin B1;Dectomax;L 701023;Doramectin A1a;Treo ACE;Treo Ace Injetavel;157544-18-8

CAS No.:

117704-25-3

Molecular Formula:

C50H74O14

InChIKeys:

InChIKey=QLFZZSKTJWDQOS-YDBLARSUSA-N

Molecular Weight:

899.11

Exact Mass:

899.11

EC Number:

1308068-626-2

HScode:

29419090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

170

XLogP3:

5.91160

Appearance:

white

Density:

1.25±0.1 g/cm3(Predicted)

Melting Point:

116-119 °C

Boiling Point:

967.4±65.0 °C(Predicted)

Flash Point:

274.4±27.8 °C

Refractive Index:

1.580

Water Solubility:

methanol: soluble

Storage Conditions:

0-6°C

Vapor Pressure:

0mmHg at 25°C

See More Doramectin Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Reproductive toxicity, Category 2

Reproductive toxicity, Additional category for effects on or via lactation

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H361 Suspected of damaging fertility or the unborn child H362 May cause harm to breast-fed children H400 Very toxic to aquatic life H410 Very toxic to aquatic life with long lasting effects
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P260 Do not breathe dust/fume/gas/mist/vapours/spray. P263 Avoid contact during pregnancy and while nursing. P273 Avoid release to the environment.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P318 IF exposed or concerned, get medical advice. P391 Collect spillage.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Doramectin Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Propylene glycol

Location:
No .41 Optics Valley Avenue, East Lake High-tech Development Zone, Wuhan ,China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment

Average lead Time:
5

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2024

Nanjing Huaman Import and Export Co., Ltd was established in 2024 with strong research and development capabilities and superb synthesis technology, as well as advanced quality control measures. Effectively promote the joint venture and cooperation with the major enterprises, manufacturers, with the idea of industrial development to serve the society and the majority of users. We always adhere to the market demand as the orientation, constantly synthesizing new high-tech chemical products , mainly exported to the United States, Europe, India, South Africa, Nigeria and other countries and regions, has a wealth of export experience, to ensure transportation safety, can let each customer as soon as possible to safely receive the goods.

Inquiry History

19 Inquiries

Country	Product	Purchase Quantity	Date Posted
Paraguay	Doramectina	60 KG	Oct 27, 2025
Ecuador	DORAMECTINA	100 KG	May 20, 2025
Ecuador	DORAMECTINA	5 KG	Mar 14, 2024
Russia	Doramectin	0.25 KG	Jul 30, 2024
Ecuador	DORAMECTINA	5 KG	Mar 7, 2024
Paraguay	Sodium lauryl ether sulphate	4000 KG	Feb 25, 2026
Paraguay	Mebendazole	100 KG	Nov 4, 2025
Paraguay	Lanolin	100 KG	Nov 4, 2025
Paraguay	Azepromacine maleate	10 KG	Oct 27, 2025
Paraguay	Fenthion	400 KG	Mar 13, 2026
Paraguay	N-Methil-2-pyrrolidone	1000 KG	Feb 25, 2026
Paraguay	Benzidamine hidrochloride	300 KG	Feb 25, 2026
Paraguay	Cefalexin compacted micronized	200 KG	Oct 27, 2025
Paraguay	Choline chloride	200 KG	Oct 27, 2025
Paraguay	Cypermethrin	3000 KG	Feb 25, 2026
Paraguay	Streptomycin sulfate	1500 BOU	May 22, 2026
Paraguay	Medroxyprogesterone acetate micronized	150 KG	May 22, 2026
Paraguay	Penicillin G sodium	2200 BOU	Mar 24, 2026
Paraguay	Cypermethrin	300 KG	Mar 24, 2026

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