High Quality Tazobactam Acid CAS 89786-04-9 Powder Fast Shipping Good Price

Tazobactam Acid More Info

Tazobactam is a β-lactamase inhibitor that is often used in combination with certain antibiotics to enhance their effectiveness against resistant bacteria. Here are some detailed aspects of Tazobactam:

Mechanism of Action

Tazobactam works by inhibiting the activity of β-lactamase enzymes produced by some bacteria. These enzymes can break down β-lactam antibiotics, making them ineffective. By inhibiting β-lactamases, Tazobactam allows the accompanying antibiotic to maintain its efficacy against bacteria that would otherwise be resistant.

Spectrum of Activity

Tazobactam is effective against a variety of bacteria that produce β-lactamases, which include:

Gram-negative bacteria: Such as Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa, which can produce extended-spectrum β-lactamases (ESBLs).

While Tazobactam itself has no significant antibacterial activity, its main role is to protect the antibiotic it is combined with from being degraded by β-lactamases.

Indications

Tazobactam is typically used in combination with antibiotics for the treatment of:

Intra-abdominal infections

Skin and soft tissue infections

Respiratory tract infections

Urinary tract infections

Other infections caused by bacteria susceptible to β-lactam antibiotics that are inactivated by β-lactamases.

Administration

Tazobactam is typically administered via intravenous (IV) infusion in combination with a β-lactam antibiotic, such as Piperacillin, to enhance its antimicrobial activity.

Side Effects

The combination therapy that includes Tazobactam can lead to:

Allergic reactions (less common, but possible)

Gastrointestinal disturbances (such as nausea and diarrhea)

Possible alterations in kidney function, particularly with prolonged use

Considerations

Patients with a known allergy to β-lactam antibiotics may also have a higher risk of allergy to Tazobactam-containing combinations.

Renal function should be monitored in patients receiving Tazobactam, as this may affect dosing and the risk of side effects.

Conclusion

Tazobactam is an important β-lactamase inhibitor that plays a crucial role in enhancing the efficacy of β-lactam antibiotics against resistant bacteria. It is essential to use Tazobactam-containing treatments judiciously to help prevent the development of antibiotic resistance and ensure effective treatment outcomes. Always consult with healthcare professionals for guidance regarding its use in specific clinical scenarios.

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

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Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express  
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Fast: 3-7 days around, high cost, door to door service

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Suitable for more than 50kg 
Fast: 3-7 days, hight cost, port to port, professional broker needed 

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Suitable for more than 500kg      
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We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders: 
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders:
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.