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Niraparib toysylate,1613220-15-7
Niraparib toysylate,1613220-15-7
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CAS No.:
1613220-15-7
Grade:
Industrial Grade
Content:
99%
Port:
xi'an
Packaging:
1KG/BAG
Price valid (until):
2025-03-15
Company Type:
Manufactory
Location:
China
Qualification:
Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceNiraparib Tosylate Monohydrate is an orally bioavailable, hydrated, tosylate salt form of niraparib, an inhibitor of poly (ADP-ribose) polymerase (PARP) types 1 and 2 (PARP-1 and -2), with antineoplastic activity. Upon administration, niraparib binds to and inhibits the activity of PARP-1 and -2, thereby inhibiting PARP-1 and -2-mediated DNA repair, enhancing the accumulation of DNA strand breaks, promoting genomic instability and resulting in apoptosis. The PARP family of proteins catalyzes post-translational ADP-ribosylation of nuclear proteins and is activated by single-strand DNA (ssDNA) breaks.Basic Info
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Product Name:
Niraparib tosylate
Other Name:MK-4827, Niraparib TsOH salt hydrate
CAS No.:1613220-15-7
Molecular Formula:C26H30N4O5S
InChIKeys:ACNPUCQQZDAPJH-FMOMHUKBSA-N
Molecular Weight:510.6052
Exact Mass:510.193695
UNII:195Q483UZD
NCI Thesaurus Code:C133238
Categories:
Characteristics-
PSA:
135.69
XLogP3:5.943
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Seller Information
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Business Type:
Manufactory
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Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Location:
https://www.dideu.com/en/
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7
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Total Annual Revenue:
Above $100 million
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Total Employees:
Above 1000
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Year of Establishment:
2016
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Certifications:
ISO Certificate,REACH
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
United States
Niraparib toysylate
5 G Feb 15, 2025 Post an enquiry for this product