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High Quality BP/EP Pharmaceutical Raw Material Brimonidine Tartrate CAS 70359-46-5

Name: High Quality BP/EP Pharmaceutical Raw Material Brimonidine Tartrate CAS 70359-46-5
Brand: HyperChem
SKU: pr2502281129
Price: 10 USD
Availability: InStock

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CAS No.:

70359-46-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

SHANGHAI

Brand:

HyperChem

Packaging:

50g/Bag, 1kg/Bag

Price valid (until):

2025-03-28

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information
Inquiry History

Description

Name	Brimonidine Tartrate
CAS number	70359-46-5
EINECS number	629-848-5
Synonym	Brimonidine Tartrate; AGN 190342; AGN-190342; AGN190342; Alphagan; UK 14,304-18; UK 14,304; UK 14304; UK-14,304-18; UK-14,308; 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine;(2R,3R)-2,3-dihydroxybutanedioic acid
Related CAS#	59803-98-4 (free base); 70359-46-5 (tartrate)
Description	Brimonidine tartrate is a selective AR, α 2 receptor, agonist used to treat glaucoma. Upon ocular administration, brimonidine tartrate acts on the blood vessels causing them to constrict which leads to a decrease in the production of aqueous humor. Brimonidine tartrate enhances the outflow of aqueous humor. This drug is used to reduce intraocular pressure.
Structure
Molecular Formula	C15H16BrN5O6
Molecular Weight	442.22 g/mol
Appearance	Solid powder
Quality Standard	BP/EP Standard
Assay	≥98%
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Store in cool place. Keep container tightly closed in a dry and well ventilated place.
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Aluminium Tin, Fiber drum
Origin	China

Brimonidine Tartrate More Info

Brimonidine tartrate is an alpha-2 adrenergic agonist used primarily in the treatment of glaucoma and ocular hypertension. It is also used to treat facial redness associated with rosacea. Brimonidine works by reducing aqueous humor production and increasing uveoscleral outflow, thereby lowering intraocular pressure.

Mechanism of Action

Brimonidine acts as an agonist of alpha-2 adrenergic receptors in the eye. This action decreases the production of aqueous humor in the ciliary body and increases uveoscleral outflow, leading to a reduction in intraocular pressure. In the skin, brimonidine reduces facial erythema by constricting blood vessels.

Applications

Brimonidine tartrate is used for:
Glaucoma and Ocular Hypertension: It is used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
Facial Redness in Rosacea: Brimonidine is used topically to reduce persistent facial erythema associated with rosacea.

Safety and Side Effects

Brimonidine can cause several side effects:
Common Side Effects (Ophthalmic Use):
Dry mouth
Blurred vision
Eye irritation
Headache
Drowsiness
Common Side Effects (Topical Use for Rosacea):
Redness or flushing (rebound effect)
Burning sensation
Pruritus (itching)
Contact dermatitis
Less Common but Serious Side Effects:
Allergic reactions (rare)
Hypotension (low blood pressure)
Bradycardia (slow heart rate)
Serious side effects require immediate medical attention.

Routes of Administration

Brimonidine tartrate is administered as eye drops for glaucoma and as a topical gel for facial redness associated with rosacea.

Pharmacokinetics

Absorption: When used as eye drops, brimonidine is absorbed systemically, with peak plasma concentrations reached within 1-4 hours.
Distribution: It has a moderate volume of distribution, indicating distribution into tissues.
Metabolism: Brimonidine is metabolized by the liver.
Elimination: The half-life of brimonidine is approximately 2-3 hours. It is primarily excreted via urine.

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
LC at sight
DP at sight

Bank transfer

PayPal

Bitcoin...

Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express
FedEx UPS DHL EMS
Fast: 3-7 days around, high cost, door to door service

By Air
Suitable for more than 50kg
Fast: 3-7 days, hight cost, port to port, professional broker needed

By Sea
Suitable for more than 500kg
Fast: 7-45 days, low cost, port to port, professional broker needed

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders:
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.

Certificates

Basic Info

Product Name:

Brimonidine tartrate

Other Name:

6-Quinoxalinamine,5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-,(2R,3R)-2,3-dihydroxybutanedioate (1:1);6-Quinoxalinamine,5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-,[R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1);Brimonidine tartrate;AGN 190342LF;Brominide tartrate;Alphagan;Alphagan P;Brimonidine Purite;Mirvaso;(5-Bromo-quinoxalin-6-yl)-(4,5-dihydro-1H-imidazol-2-yl)-amine L-tartrate;109826-56-4;79570-19-7

CAS No.:

70359-46-5

Molecular Formula:

C11H10BrN5.C4H6O6

InChIKeys:

InChIKey=QZHBYNSSDLTCRG-LREBCSMRSA-N

Molecular Weight:

442.22

Exact Mass:

441.028381

EC Number:

1308068-626-2

UNII:

4S9CL2DY2H

NCI Thesaurus Code:

C47419

ATC Code:

S01EC54|D11AX21

HScode:

2933990090

Categories:

Ophthalmic Agents

Characteristics

PSA:

177

XLogP3:

-0.52180

Appearance:

Off-white crystalline solid

Melting Point:

207.5 °C

Boiling Point:

432.6°C at 760 mmHg

Flash Point:

215.4ºC

Storage Conditions:

-20°C Freezer

See More Brimonidine tartrate Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 3, Oral

Specific target organ toxicity â repeated exposure, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H301 Toxic if swallowed H373 May cause damage to organs through prolonged or repeated exposure
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P319 Get medical help if you feel unwell.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Brimonidine tartrate Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Certifications:
Certification Report by Bureau Veritas

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	brimonidine tartrate	20 G	Feb 7, 2025

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